The OPUS (Outcomes Following Vaginal Prolapse Repair and Midurethral Sling) trial examined the effect of a prophylactic midurethral sling at the time of vaginal prolapse surgery in women without stress urinary incontinence. Women undergoing surgery for pelvic organ prolapse are at risk for developing postoperative stress urinary incontinence even if they do not complain of it preoperatively. This was a randomized controlled trial with intervention patients in the prophylactic midurethral sling group and control patients in the sham group. The authors identified a lower rate of de novo urinary incontinence at 3 and 12 months in women who received a prophylactic midurethral sling at the time of vaginal prolapse surgery. However, they also found higher rates of adverse events. This study provides valuable information for patient counseling and surgical decision-making with respect to concurrent prolapse and incontinence surgeries.