Solution using Stomahesive® wafers for allergic contact dermatitis caused by isobornyl acrylate in glucose monitoring sensors

Author(s):  
Kay Lin Ng ◽  
Rosemary L. Nixon ◽  
Claire Grills ◽  
Mei Mui Tam

2018 ◽  
Vol 12 (3) ◽  
pp. 630-633 ◽  
Author(s):  
Stefanie Kamann ◽  
Olivier Aerts ◽  
Lutz Heinemann

In the past decade, new diabetes technologies, including continuous glucose monitoring (CGM) systems, support patients with diabetes in their daily struggle with achieving a good glucose control. However, shortly after the first CGM systems appeared on the market, also the first concerns about adverse skin reactions were raised. Most patients claimed to suffer from (sometimes severe) skin irritation, or even allergy, which they related to the (acrylate-based) adhesive part of the device. For a long time the actual substance that caused these skin reactions with, for example, the Flash Glucose Monitoring system (iscCGM; Freestyle® Libre) could not be identified; however, recently Belgian and Swedish dermatologists reported that the majority of their patients that have developed a contact-allergic while using iscCGM react sensitively to a specific acrylate, that is, isobornyl acrylate (IBOA). Subsequently they showed by means of gas chromatography-mass spectrometry that this substance is present in the case of the glucose sensor attached by an adhesive to the skin. We report three additional cases from Germany, including a 10-year-old boy, suffering from severe allergic contact dermatitis to IBOA.



2019 ◽  
Vol 81 (3) ◽  
pp. 219-220 ◽  
Author(s):  
Ignacio Jáuregui ◽  
Javier Sánchez ◽  
Aritza Segurola ◽  
Cristina Galán ◽  
Yolanda Seras ◽  
...  


2018 ◽  
Vol 79 (5) ◽  
pp. 320-321 ◽  
Author(s):  
Monica Corazza ◽  
Valeria Scuderi ◽  
Dario Musmeci ◽  
Caterina Foti ◽  
Paolo Romita ◽  
...  


2019 ◽  
Vol 14 (3) ◽  
pp. 582-585 ◽  
Author(s):  
Stefanie Kamann ◽  
Lutz Heinemann ◽  
Eva Oppel

Background: Continuous glucose monitoring (CGM) systems replace more and more capillary self-monitoring of blood glucose by patients with diabetes. However, at least a subset of patients experience adverse skin reactions such as severe allergic contact dermatitis (ACD) after prolonged usage of CGM systems. A major allergen isobornyl acrylate (IBOA) has been identified recently. Objectives: After developing an ACD, patients have difficulties in continuing the usage of their CGM system (and also of, eg, certain patch pumps). Most of such patients look for possibilities to continue the usage of, eg, a CGM system that requires intermittent scanning (iscCGM, Freestyle Libre). Patients and Methods: Eight patients with a known ACD were supplied with different hydrocolloid-based plasters ( n = 5 with Hansaplast blister plaster, n = 2 with Cutimed Hydro B from BSN, and n = 1 with Stomahesive baseplate from Convatec). They attached these plasters to their skin underneath their iscCGM system. Results: All patients were able to continue the usage of this iscCGM system when using such plasters. Conclusion: Patients with ACD benefit from the usage of such plasters; however, some limitations have to be acknowledged.





1977 ◽  
Vol 113 (8) ◽  
pp. 1058-1061 ◽  
Author(s):  
D. K. Goette




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