Effects of glaucoma surgery on visual field progression in open‐angle glaucoma considering the floor effect

Purpose To evaluate the relationship of central corneal thickness (CCT) to baseline visual field parameters and visual field progression in patients with primary open-angle glaucoma (POAG). Methods Charts of consecutive patients with POAG were reviewed to obtain visual field data. Visual field was measured by standard threshold static perimetry. Variables analyzed included mean deviation (MD) and pattern standard deviation (PSD). Results A total of 121 eyes examined over 4 years were evaluated. A significant negative relationship between CCT and PSD (correlation coefficient: −0.02, p<0.05) was found. Analyses comparing CCT to change in PSD and MD (visual field progression) were statistically not significant. Conclusions Patients with thinner corneas initially present with a greater visual field defect, indicating that thin corneas may contribute to advanced glaucomatous damage at the time of diagnosis. However, CCT does not seem to be a significant risk factor for progression of the disease.

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A Small Disc Area Is a Risk Factor for Visual Field Loss Progression in Primary Open-Angle Glaucoma: The Glaucoma Stereo Analysis Study

Journal of Ophthalmology ◽

10.1155/2018/8941489 ◽

2018 ◽

Vol 2018 ◽

pp. 1-6 ◽

Cited By ~ 1

Author(s):

Yasushi Kitaoka ◽

Masaki Tanito ◽

Yu Yokoyama ◽

Koji Nitta ◽

Maki Katai ◽

...

Keyword(s):

Visual Field ◽

Primary Open Angle Glaucoma ◽

Open Angle Glaucoma ◽

Visual Field Loss ◽

Morphological Parameters ◽

Open Angle ◽

Analysis Study ◽

Visual Field Progression ◽

Stereo Analysis ◽

Disc Area

Purpose. The Glaucoma Stereo Analysis Study, a cross-sectional multicenter collaborative study, used a stereo fundus camera (nonmyd WX) to assess various morphological parameters of the optic nerve head (ONH) in glaucoma patients. We compared the associations of each parameter between the visual field loss progression group and no-progression group. Methods. The study included 187 eyes of 187 patients with primary open-angle glaucoma or normal-tension glaucoma. We divided the mean deviation (MD) slope values of all patients into the progression group (<−0.3 dB/year) and no-progression group (≧−0.3 dB/year). ONH morphological parameters were calculated with prototype analysis software. The correlations between glaucomatous visual field progression and patient characteristics or each ONH parameter were analyzed with Spearman’s rank correlation coefficient. Results. The MD slope averages in the progression group and no-progression group were −0.58 ± 0.28 dB/year and 0.05 ± 0.26 dB/year, respectively. Among disc parameters, vertical disc width (diameter), disc area, cup area, and cup volume in the progression group were significantly less than those in the no-progression group. Logistic regression analysis revealed a significant association between the visual field progression and disc area (odds ratio 0.49/mm2 disc area). Conclusion. A smaller disc area may be associated with more rapid glaucomatous visual field progression.

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Investigating the usefulness of a cluster-based trend analysis to detect visual field progression in patients with open-angle glaucoma

British Journal of Ophthalmology ◽

10.1136/bjophthalmol-2016-310069 ◽

2017 ◽

Vol 101 (12) ◽

pp. 1658-1665 ◽

Cited By ~ 7

Author(s):

Shuichiro Aoki ◽

Hiroshi Murata ◽

Yuri Fujino ◽

Masato Matsuura ◽

Atsuya Miki ◽

...

Keyword(s):

Visual Field ◽

Trend Analysis ◽

Open Angle Glaucoma ◽

Open Angle ◽

Visual Field Progression

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Comparison of visual field progression in new-diagnosed primary open-angle and exfoliation glaucoma patients in Sweden.

10.21203/rs.3.rs-34864/v2 ◽

2020 ◽

Author(s):

Marcelo Ayala

Keyword(s):

Visual Field ◽

Primary Open Angle Glaucoma ◽

Open Angle Glaucoma ◽

T Test ◽

Open Angle ◽

Visual Field Progression ◽

Exfoliation Glaucoma ◽

The Difference ◽

Glaucoma Group

Abstract Background: The present study aimed to compare visual field progression in new-diagnosed exfoliation versus open-angle glaucoma patients. Methods: Retrospective study. The study included patients with new-diagnosed primary open-angle and exfoliation glaucoma. All patients were followed for three years with reliable visual fields. At least five reliable fields were needed for inclusion. Exfoliation and open-angle glaucoma were defined based on the European Glaucoma Society guidelines. Visual field evaluation was performed using the software threshold 24-2 of the Humphrey Field Analysis. Outcomes: Visual field progression. For visual field progression, three different strategies were used: mean deviation (MD), visual field index (VFI), and the guided progression analysis (GPA). Results: The study included 128 subjects, of the 54 in the open-angle and 74 in the exfoliation glaucoma group. The MD difference values were higher in the exfoliation (-3.17 dB) than in the primary open-angle (-1.25 dB) glaucoma group in the three-year follow-up period. The difference between groups was significant (t-test, p=<0.001). The difference in VFI was calculated for the three years follow-up period. The difference was higher in the exfoliation (-7.65%) than in the primary open (-1.90%) glaucoma group (t-test, p=<0.001). The GPA showed progression in 58% of cases in exfoliation, and 13% in primary open glaucoma group (Chi-square, p=<0.001). Conclusion: The present study found a more frequent and faster visual field progression in exfoliation than in primary open-angle glaucoma patients. New-diagnosed exfoliation glaucoma patients must be controlled and treated more strictly than primary open-angle glaucoma patients to avoid visual field deterioration.

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