scholarly journals Editorial: tailoring mycophenolate mofetil rescue therapy for success in autoimmune hepatitis

2019 ◽  
Vol 49 (11) ◽  
pp. 1449-1450 ◽  
Author(s):  
Albert J. Czaja
Keyword(s):  
Mycophenolate Mofetil ◽  
Autoimmune Hepatitis ◽  
Rescue Therapy

scholarly journals Editorial: tailoring mycophenolate mofetil rescue therapy for success in autoimmune hepatitis-authors' reply

2019 ◽  
Vol 49 (11) ◽  
pp. 1450-1451
Author(s):  
Amanda J. Nicoll ◽  
Stuart K. Roberts ◽  
Simone I. Strasser ◽  
Keyword(s):  
Mycophenolate Mofetil ◽  
Autoimmune Hepatitis ◽  
Rescue Therapy

scholarly journals Efficacy and Safety of Mycophenolate Mofetil and Tacrolimus as Second-line Therapy for Patients With Autoimmune Hepatitis

2017 ◽  
Vol 15 (12) ◽  
pp. 1950-1956.e1 ◽  
Author(s):  
Cumali Efe ◽  
Hannes Hagström ◽  
Henriette Ytting ◽  
Rahima A. Bhanji ◽  
Niklas F. Müller ◽  
...  
Keyword(s):  
Mycophenolate Mofetil ◽  
Autoimmune Hepatitis ◽  
Second Line ◽  
Efficacy And Safety ◽  
Second Line Therapy ◽  
Line Therapy

Comparison of mycophenolate mofetil with standard treatment for autoimmune hepatitis

2019 ◽  
Vol 31 (7) ◽  
pp. 873-877 ◽  
Author(s):  
Zhen-Jun Yu ◽  
Lu-Lu Zhang ◽  
Ting-Ting Huang ◽  
Jian-Sheng Zhu ◽  
Ze-Bao He
Keyword(s):  
Mycophenolate Mofetil ◽  
Autoimmune Hepatitis ◽  
Standard Treatment

scholarly journals Mycophenolate Mofetil for the Treatment of Autoimmune Hepatitis in Patients Refractory to Standard Therapy

2004 ◽  
Vol 18 (5) ◽  
pp. 321-326 ◽  
Author(s):  
Shane M Devlin ◽  
Mark G Swain ◽  
Stefan J Urbanski ◽  
Kelly W Burak
Keyword(s):  
Mycophenolate Mofetil ◽  
Autoimmune Hepatitis ◽  
Alanine Aminotransferase ◽  
Standard Therapy ◽  
Conventional Treatment ◽  
Case Series ◽  
Therapeutic Options ◽  
Sparing Effect ◽  
Histological Remission ◽  
Steroid Sparing

There are limited therapeutic options available for patients with autoimmune hepatitis in whom conventional treatment fails. A case series of five patients unresponsive to or unable to take azathioprine, 6-mercaptopurine or corticosteroids who were treated with mycophenolate mofetil (MMF) is reported. While on MMF, alanine aminotransferase normalized or remained normal in all patients. MMF had a steroid-sparing effect and histological remission was demonstrated in one patient after seven months of MMF. One patient experienced an uncomplicated episode of pyelonephritis. In conclusion, MMF can effectively induce and maintain remission in refractory autoimmune hepatitis patients.

scholarly journals Postinfantile Giant Cell Hepatitis with Features of Acute Severe Autoimmune Hepatitis Probably Triggered by Diclofenac in a Patient with Primary Myelofibrosis

2018 ◽  
Vol 2018 ◽  
pp. 1-5 ◽  
Author(s):  
Pinelopi Arvaniti ◽  
Kalliopi Zachou ◽  
George K. Koukoulis ◽  
George N. Dalekos
Keyword(s):  
Liver Disease ◽  
Autoimmune Hepatitis ◽  
Giant Cell ◽  
Liver Diseases ◽  
Acute Liver Injury ◽  
Rescue Therapy ◽  
Primary Myelofibrosis ◽  
Life Saving ◽  
History Of ◽  
Giant Cell Hepatitis

Giant cell hepatitis (GCH) is commonly reported in neonatal and infantile liver diseases but rarely in adults where the term postinfantile GCH (PIGCH) is used. PIGCH is associated with many diseases, including drugs toxicity, viruses, and autoimmune liver diseases, with autoimmune hepatitis (AIH) being the most prevalent. We present a case of PIGCH in a 76-year-old female without known history of liver disease who suffered from an acute severe episode of hepatitis. After careful exclusion of other hepatitis causes by imaging, virological, immunological, and microbiological investigations, a diagnosis of acute severe AIH (AS-AIH) was established. The patient was started on corticosteroids but she did not respond and died 3 days later because of advanced acute liver failure. Postmortem liver biopsy showed typical PIGCH lesions. Physicians must keep this catastrophic entity in mind in cases of unexplained acute liver injury as, contrary to our case, prompt rescue therapy with corticosteroids may be life-saving.

683 Mycophenolate mofetil improves liver tests in patients with autoimmune hepatitis (AIH)

Hepatology ◽  
2003 ◽  
Vol 38 ◽  
pp. 490-490 ◽  
Author(s):  
A ADAMS ◽  
R GISH ◽  
E WAKIL ◽  
N BZOWEJ ◽  
E DOO ◽  
...  
Keyword(s):  
Mycophenolate Mofetil ◽  
Autoimmune Hepatitis ◽  
Liver Tests

Sirolimus as Rescue Therapy in Pediatric Autoimmune Hepatitis

2014 ◽  
Vol 58 (1) ◽  
pp. e4-e6 ◽  
Author(s):  
Jacob Kurowski ◽  
Hector Melin-Aldana ◽  
Lee Bass ◽  
Estella M. Alonso ◽  
Udeme D. Ekong
Keyword(s):  
Autoimmune Hepatitis ◽  
Rescue Therapy
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