Mycophenolate mofetil as a rescue therapy for autoimmune hepatitis patients who are not responsive to standard therapy

2011 ◽  
Vol 5 (4) ◽  
pp. 517-522 ◽  
Author(s):  
Hind I Fallatah ◽  
Hisham O Akbar
2004 ◽  
Vol 18 (5) ◽  
pp. 321-326 ◽  
Author(s):  
Shane M Devlin ◽  
Mark G Swain ◽  
Stefan J Urbanski ◽  
Kelly W Burak

There are limited therapeutic options available for patients with autoimmune hepatitis in whom conventional treatment fails. A case series of five patients unresponsive to or unable to take azathioprine, 6-mercaptopurine or corticosteroids who were treated with mycophenolate mofetil (MMF) is reported. While on MMF, alanine aminotransferase normalized or remained normal in all patients. MMF had a steroid-sparing effect and histological remission was demonstrated in one patient after seven months of MMF. One patient experienced an uncomplicated episode of pyelonephritis. In conclusion, MMF can effectively induce and maintain remission in refractory autoimmune hepatitis patients.


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Amanda J. Nicoll ◽  
Stuart K. Roberts ◽  
Simone I. Strasser ◽  

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Author(s):  
Stuart K. Roberts ◽  
Ricky Lim ◽  
Simone Strasser ◽  
Amanda Nicoll ◽  
Alessia Gazzola ◽  
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2003 ◽  
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pp. A785 ◽  
Author(s):  
Sajid Jalil ◽  
Ahmet Gurakar ◽  
Harlan Wright ◽  
Ted Bader ◽  
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...  

2017 ◽  
Vol 15 (12) ◽  
pp. 1950-1956.e1 ◽  
Author(s):  
Cumali Efe ◽  
Hannes Hagström ◽  
Henriette Ytting ◽  
Rahima A. Bhanji ◽  
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2019 ◽  
Vol 31 (7) ◽  
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Lu-Lu Zhang ◽  
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Jian-Sheng Zhu ◽  
Ze-Bao He

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