Physiologically based pharmacokinetic modelling to predict exposure differences in healthy volunteers and subjects with renal impairment: Ceftazidime case study

Prediction of Drug-Drug Interaction between Tacrolimus and Principal Ingredients of Wuzhi Capsule in Chinese Healthy Volunteers Using Physiologically-Based Pharmacokinetic Modelling

Basic & Clinical Pharmacology & Toxicology ◽

10.1111/bcpt.12914 ◽

2017 ◽

Vol 122 (3) ◽

pp. 331-340 ◽

Cited By ~ 11

Author(s):

Hongyan Zhang ◽

Fengjiao Bu ◽

Lei Li ◽

Zheng Jiao ◽

Guo Ma ◽

...

Keyword(s):

Drug Interaction ◽

Healthy Volunteers ◽

Physiologically Based ◽

Drug Drug Interaction ◽

Wuzhi Capsule

Towards Quantitation of the Effects of Renal Impairment and Probenecid Inhibition on Kidney Uptake and Efflux Transporters, Using Physiologically Based Pharmacokinetic Modelling and Simulations

Clinical Pharmacokinetics ◽

10.1007/s40262-013-0117-y ◽

2014 ◽

Vol 53 (3) ◽

pp. 283-293 ◽

Cited By ~ 54

Author(s):

Vicky Hsu ◽

Manuela de L. T. Vieira ◽

Ping Zhao ◽

Lei Zhang ◽

Jenny Huimin Zheng ◽

...

Keyword(s):

Renal Impairment ◽

Efflux Transporters ◽

Physiologically Based ◽

Modelling And Simulations

Physiologically based pharmacokinetic modelling of treprostinil after intravenous injection and extended‐release oral tablet administration in healthy volunteers: An extrapolation to other patient populations including patients with hepatic impairment

British Journal of Clinical Pharmacology ◽

10.1111/bcp.14966 ◽

2021 ◽

Author(s):

Xuemei Wu ◽

Xiaohan Zhang ◽

Ruichao Xu ◽

Imam Hussain Shaik ◽

Raman Venkataramanan

Keyword(s):

Healthy Volunteers ◽

Intravenous Injection ◽

Hepatic Impairment ◽

Extended Release ◽

Oral Tablet ◽

Physiologically Based Pharmacokinetic Modelling of Glycopyrronium in Patients With Renal Impairment

Journal of Pharmaceutical Sciences ◽

10.1016/j.xphs.2020.03.014 ◽

2021 ◽

Vol 110 (1) ◽

pp. 438-445 ◽

Cited By ~ 1

Author(s):

Mitsuo Higashimori ◽

Kensuke Ishikawa ◽

Michael Gillen ◽

Diansong Zhou

Keyword(s):

Renal Impairment ◽

Physiologically based pharmacokinetic modelling to support the clinical management of drug‐drug interactions with bictegravir

Clinical Pharmacology & Therapeutics ◽

10.1002/cpt.2221 ◽

2021 ◽

Author(s):

Felix Stader ◽

Manuel Battegay ◽

Catia Marzolini

Keyword(s):

Drug Interactions ◽

Clinical Management ◽

Prediction of olanzapine exposure in individual patients using physiologically based pharmacokinetic modelling and simulation

British Journal of Clinical Pharmacology ◽

10.1111/bcp.13480 ◽

2018 ◽

Vol 84 (3) ◽

pp. 462-476 ◽

Cited By ~ 22

Author(s):

Thomas M. Polasek ◽

Geoffrey T. Tucker ◽

Michael J. Sorich ◽

Michael D. Wiese ◽

Titus Mohan ◽

...

Keyword(s):

Modelling And Simulation ◽

Physiologically based pharmacokinetic modelling: a sub-compartmentalized model of tissue distribution

Journal of Pharmacokinetics and Pharmacodynamics ◽

10.1007/s10928-007-9071-3 ◽

2007 ◽

Vol 34 (6) ◽

pp. 789-806 ◽

Cited By ~ 26

Author(s):

Max von Kleist ◽

Wilhelm Huisinga

Keyword(s):

Tissue Distribution ◽

Physiologically‐based pharmacokinetic modelling to predict oprozomib CYP3A drug–drug interaction potential in patients with advanced malignancies

British Journal of Clinical Pharmacology ◽

10.1111/bcp.13817 ◽

2018 ◽

Vol 85 (3) ◽

pp. 530-539 ◽

Cited By ~ 1

Author(s):

Ying Ou ◽

Yang Xu ◽

Lia Gore ◽

R. Donald Harvey ◽

Alain Mita ◽

...

Keyword(s):

Drug Interaction ◽

Interaction Potential ◽

Advanced Malignancies ◽

Physiologically Based ◽

Drug Drug Interaction

Development of a Korean‐specific virtual population for physiologically based pharmacokinetic modelling and simulation

Biopharmaceutics & Drug Disposition ◽

10.1002/bdd.2178 ◽

2019 ◽

Vol 40 (3-4) ◽

pp. 135-150 ◽

Cited By ~ 3

Author(s):

Yun Kim ◽

Oliver Hatley ◽

Su‐jin Rhee ◽

Sojeong Yi ◽

Hyun A. Lee ◽

...

Keyword(s):

Modelling And Simulation ◽

Virtual Population ◽

Physiologically-based pharmacokinetic modelling of immune, reproductive and carcinogenic effects from contaminant exposure in polar bears (Ursus maritimus) across the Arctic

Environmental Research ◽

10.1016/j.envres.2015.03.011 ◽

2015 ◽

Vol 140 ◽

pp. 45-55 ◽

Cited By ~ 52

Author(s):

Rune Dietz ◽

Kim Gustavson ◽

Christian Sonne ◽

Jean-Pierre Desforges ◽

Frank F. Rigét ◽

...

Keyword(s):

Ursus Maritimus ◽

The Arctic ◽

Polar Bears ◽

Contaminant Exposure ◽

Physiologically Based ◽

Carcinogenic Effects