physiologically based pharmacokinetic modelling Latest Research Papers

Evaluation of the Drug–Drug Interaction Potential of Treosulfan using a Physiologically‐Based Pharmacokinetic Modelling Approach

British Journal of Clinical Pharmacology ◽

10.1111/bcp.15081 ◽

2021 ◽

Author(s):

Stephan Schaller ◽

Frederico S. Martins ◽

Pavel Balazki ◽

Sonja Böhm ◽

Joachim Baumgart ◽

...

Keyword(s):

Drug Interaction ◽

Interaction Potential ◽

Pharmacokinetic Modelling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based Pharmacokinetic Modelling ◽

Physiologically Based ◽

Drug Drug Interaction ◽

Modelling Approach

Correction to: Physiologically based pharmacokinetic modelling to predict the clinical effect of CYP3A inhibitors/inducers on esaxerenone pharmacokinetics in healthy subjects and subjects with hepatic impairment

European Journal of Clinical Pharmacology ◽

10.1007/s00228-021-03211-z ◽

2021 ◽

Author(s):

Akiko Watanabe ◽

Tomoko Ishizuka ◽

Makiko Yamada ◽

Yoshiyuki Igawa ◽

Takako Shimizu ◽

...

Keyword(s):

Hepatic Impairment ◽

Healthy Subjects ◽

Clinical Effect ◽

Pharmacokinetic Modelling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based Pharmacokinetic Modelling ◽

Physiologically Based

Physiologically-Based Pharmacokinetic Modelling of Entrectinib Parent and Active Metabolite to Support Regulatory Decision-Making

European Journal of Drug Metabolism and Pharmacokinetics ◽

10.1007/s13318-021-00714-z ◽

2021 ◽

Author(s):

Nassim Djebli ◽

Vincent Buchheit ◽

Neil Parrott ◽

Elena Guerini ◽

Yumi Cleary ◽

...

Keyword(s):

Decision Making ◽

Active Metabolite ◽

Pharmacokinetic Modelling ◽

Regulatory Decision ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based Pharmacokinetic Modelling ◽

Physiologically Based

Physiologically based pharmacokinetic modelling to investigate the impact of the cytokine storm on CYP3A drug pharmacokinetics in COVID‐19 patients

Clinical Pharmacology & Therapeutics ◽

10.1002/cpt.2402 ◽

2021 ◽

Author(s):

Felix Stader ◽

Manuel Battegay ◽

Parham Sendi ◽

Catia Marzolini

Keyword(s):

Cytokine Storm ◽

Pharmacokinetic Modelling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based Pharmacokinetic Modelling ◽

Physiologically Based ◽

The Impact ◽

Drug Pharmacokinetics

Physiologically Based Pharmacokinetic Modelling of Inhaled Nemiralisib: Mechanistic Components for Pulmonary Absorption, Systemic Distribution, and Oral Absorption

Clinical Pharmacokinetics ◽

10.1007/s40262-021-01066-2 ◽

2021 ◽

Author(s):

Neil A. Miller ◽

Rebecca H. Graves ◽

Chris D. Edwards ◽

Augustin Amour ◽

Ed Taylor ◽

...

Keyword(s):

Oral Absorption ◽

Pulmonary Absorption ◽

Pharmacokinetic Modelling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based Pharmacokinetic Modelling ◽

Systemic Distribution ◽

Physiologically Based

Physiologically based pharmacokinetic modelling of acetaminophen in preterm neonates ‐ the impact of metabolising enzyme ontogeny and reduced cardiac output

Biopharmaceutics & Drug Disposition ◽

10.1002/bdd.2301 ◽

2021 ◽

Author(s):

Olusola Olafuyi ◽

Mohammad Abbasi ◽

Karel Allegaert

Keyword(s):

Cardiac Output ◽

Preterm Neonates ◽

Pharmacokinetic Modelling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based Pharmacokinetic Modelling ◽

Physiologically Based ◽

The Impact

Crosstalk of physiological pH and chemical pKa under the umbrella of physiologically based pharmacokinetic modelling of drug absorption, distribution, metabolism, excretion and toxicity

Expert Opinion on Drug Metabolism & Toxicology ◽

10.1080/17425255.2021.1951223 ◽

2021 ◽

Author(s):

Lu Gaohua ◽

Xiusheng Miao ◽

Liu Dou

Keyword(s):

Drug Absorption ◽

Pharmacokinetic Modelling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based Pharmacokinetic Modelling ◽

Physiologically Based

Physiologically based pharmacokinetic modelling of treprostinil after intravenous injection and extended‐release oral tablet administration in healthy volunteers: An extrapolation to other patient populations including patients with hepatic impairment

British Journal of Clinical Pharmacology ◽

10.1111/bcp.14966 ◽

2021 ◽

Author(s):

Xuemei Wu ◽

Xiaohan Zhang ◽

Ruichao Xu ◽

Imam Hussain Shaik ◽

Raman Venkataramanan

Keyword(s):

Healthy Volunteers ◽

Intravenous Injection ◽

Hepatic Impairment ◽

Extended Release ◽

Pharmacokinetic Modelling ◽

Oral Tablet ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based Pharmacokinetic Modelling ◽

Physiologically Based

Personalise vitamin D 3 using physiologically based pharmacokinetic modelling

CPT Pharmacometrics & Systems Pharmacology ◽

10.1002/psp4.12640 ◽

2021 ◽

Author(s):

Zhonghui Huang ◽

Tao You

Keyword(s):

Vitamin D ◽

Pharmacokinetic Modelling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based Pharmacokinetic Modelling ◽

Physiologically Based ◽

Vitamin D 3

Physiologically based pharmacokinetic modelling to support the clinical management of drug‐drug interactions with bictegravir

Clinical Pharmacology & Therapeutics ◽

10.1002/cpt.2221 ◽

2021 ◽

Author(s):

Felix Stader ◽

Manuel Battegay ◽

Catia Marzolini

Keyword(s):

Drug Interactions ◽

Clinical Management ◽

Pharmacokinetic Modelling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based Pharmacokinetic Modelling ◽

Physiologically Based

physiologically based pharmacokinetic modelling
Recently Published Documents

TOTAL DOCUMENTS

H-INDEX

Evaluation of the Drug–Drug Interaction Potential of Treosulfan using a Physiologically‐Based Pharmacokinetic Modelling Approach

Correction to: Physiologically based pharmacokinetic modelling to predict the clinical effect of CYP3A inhibitors/inducers on esaxerenone pharmacokinetics in healthy subjects and subjects with hepatic impairment

Physiologically-Based Pharmacokinetic Modelling of Entrectinib Parent and Active Metabolite to Support Regulatory Decision-Making

Physiologically based pharmacokinetic modelling to investigate the impact of the cytokine storm on CYP3A drug pharmacokinetics in COVID‐19 patients

Physiologically Based Pharmacokinetic Modelling of Inhaled Nemiralisib: Mechanistic Components for Pulmonary Absorption, Systemic Distribution, and Oral Absorption

Physiologically based pharmacokinetic modelling of acetaminophen in preterm neonates ‐ the impact of metabolising enzyme ontogeny and reduced cardiac output

Crosstalk of physiological pH and chemical pKa under the umbrella of physiologically based pharmacokinetic modelling of drug absorption, distribution, metabolism, excretion and toxicity

Physiologically based pharmacokinetic modelling of treprostinil after intravenous injection and extended‐release oral tablet administration in healthy volunteers: An extrapolation to other patient populations including patients with hepatic impairment

Personalise vitamin D 3 using physiologically based pharmacokinetic modelling

Physiologically based pharmacokinetic modelling to support the clinical management of drug‐drug interactions with bictegravir

Export Citation Format

physiologically based pharmacokinetic modellingRecently Published Documents

TOTAL DOCUMENTS

H-INDEX

Evaluation of the Drug–Drug Interaction Potential of Treosulfan using a Physiologically‐Based Pharmacokinetic Modelling Approach

Correction to: Physiologically based pharmacokinetic modelling to predict the clinical effect of CYP3A inhibitors/inducers on esaxerenone pharmacokinetics in healthy subjects and subjects with hepatic impairment

Physiologically-Based Pharmacokinetic Modelling of Entrectinib Parent and Active Metabolite to Support Regulatory Decision-Making

Physiologically based pharmacokinetic modelling to investigate the impact of the cytokine storm on CYP3A drug pharmacokinetics in COVID‐19 patients

Physiologically Based Pharmacokinetic Modelling of Inhaled Nemiralisib: Mechanistic Components for Pulmonary Absorption, Systemic Distribution, and Oral Absorption

Physiologically based pharmacokinetic modelling of acetaminophen in preterm neonates ‐ the impact of metabolising enzyme ontogeny and reduced cardiac output

Crosstalk of physiological pH and chemical pKa under the umbrella of physiologically based pharmacokinetic modelling of drug absorption, distribution, metabolism, excretion and toxicity

Physiologically based pharmacokinetic modelling of treprostinil after intravenous injection and extended‐release oral tablet administration in healthy volunteers: An extrapolation to other patient populations including patients with hepatic impairment

Personalise vitamin D 3 using physiologically based pharmacokinetic modelling

Physiologically based pharmacokinetic modelling to support the clinical management of drug‐drug interactions with bictegravir

physiologically based pharmacokinetic modelling
Recently Published Documents