Human herpesvirus 6 involvement in paediatric drug hypersensitivity syndrome

2015 ◽  
Vol 172 (4) ◽  
pp. 858-859 ◽  
Author(s):  
V. Descamps
Keyword(s):  
Drug Hypersensitivity ◽  
Human Herpesvirus ◽  
Hypersensitivity Syndrome ◽  
Human Herpesvirus 6 ◽  
Paediatric Drug ◽  
Herpesvirus 6 ◽  
Drug Hypersensitivity Syndrome

Drug Hypersensitivity Syndrome Caused by Minocycline

2006 ◽  
Vol 10 (3) ◽  
pp. 131-135 ◽  
Author(s):  
Daisuke Tsuruta ◽  
Yukiko Someda ◽  
Junko Sowa ◽  
Hiromi Kobayashi ◽  
Masamitsu Ishii
Keyword(s):  
Drug Hypersensitivity ◽  
Human Herpesvirus ◽  
Oral Prednisolone ◽  
Liver Function Tests ◽  
Hypersensitivity Syndrome ◽  
Skin Lesions ◽  
Japanese Woman ◽  
Barr Virus ◽  
Epstein Barr ◽  
Drug Hypersensitivity Syndrome

Background: Minocycline is a commonly prescribed drug for the treatment of acne. Its use is generally not associated with systemic side effects. Objective: To describe a case of minocycline-induced drug hypersensitivity syndrome in a 20-year-old Japanese woman. Methods and Results: Following 2 months of minocycline treatment, the patient developed skin lesions composed of exudative maculopapules, purpuratous macules, and target-like, erythema multiforme-like plaques over most of her body. In addition, she had fever, abnormal liver function tests, eosinophilia, and atypical lymphocytosis. Laboratory tests indicated no elevation of antibody titers against cytomegalovirus, Epstein-Barr virus, and human herpesvirus 6. Her ongoing exposure to minocycline was stopped, and treatment with oral prednisolone was begun. Her signs, symptoms, and laboratory abnormalities then began to resolve. Subsequently, the syndrome was observed to return briefly in response to an oral challenge with minocycline. Conclusions: Minocycline is able to elicit a drug hypersensitivity syndrome that can resemble infectious mononucleosis. This drug reaction can be treated effectively by cessation of exposure to this drug and steroid therapy.

Detection of human herpesvirus-6 transcripts in carbamazepine-induced hypersensitivity syndrome by in situ hybridization

2009 ◽  
Vol 54 (2) ◽  
pp. 134-136 ◽  
Author(s):  
Takahiro Watanabe ◽  
Hiroko Nakashima ◽  
Hanako Ohmatsu ◽  
Naoki Sakurai ◽  
Tomonori Takekoshi ◽  
...  
Keyword(s):  
In Situ Hybridization ◽  
Human Herpesvirus ◽  
Hypersensitivity Syndrome ◽  
Human Herpesvirus 6 ◽  
Herpesvirus 6

scholarly journals Severe Hypersensitivity Syndrome Due to Sulfasalazine Associated With Reactivation of Human Herpesvirus 6

1998 ◽  
Vol 134 (9) ◽  
Author(s):  
Mikiko Tohyama ◽  
Yoko Yahata ◽  
Masaki Yasukawa ◽  
Reiko Inagi ◽  
Yoshio Urano ◽  
...  
Keyword(s):  
Human Herpesvirus ◽  
Hypersensitivity Syndrome ◽  
Human Herpesvirus 6 ◽  
Herpesvirus 6

ATL-like marked atypical lymphocytosis associated with drug-induced hypersensitivity syndrome and human herpesvirus-6 reactivation

2009 ◽  
Vol 90 (5) ◽  
pp. 648-650 ◽  
Author(s):  
Tomonori Nakazato ◽  
Kazuhito Suzuki ◽  
Ai Mihara ◽  
Yukinari Sanada ◽  
Yoshinobu Aisa ◽  
...  
Keyword(s):  
Human Herpesvirus ◽  
Hypersensitivity Syndrome ◽  
Human Herpesvirus 6 ◽  
Drug Induced ◽  
Herpesvirus 6
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