Increased Frequency of Heart Transplantation, Shortened Waitlist Time and Preserved Post‐Transplant Survival in Adults with Congenital Heart Disease, on the New Heart Transplant Allocation System

2020 ◽  
Author(s):  
Milena Jani ◽  
Stephen Cook ◽  
Si Hong Huang ◽  
Theodore Boeve ◽  
Marzia Leacche ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Heart Transplantation ◽  
Heart Transplant ◽  
Congenital Heart ◽  
Transplant Survival ◽  
Allocation System ◽  
Post Transplant

Abstract 18971: Heart Transplantation for Adult Patients With Congenital Heart Disease: Are the Outcomes Still Worse Than in the General Population in 2015?

Circulation ◽  
2015 ◽  
Vol 132 (suppl_3) ◽  
Author(s):  
Diego Moguillansky ◽  
Biagio A Pietra ◽  
Frederick J Fricker ◽  
Mark S Bleiweis
Keyword(s):  
Congenital Heart Disease ◽  
Survival Analysis ◽  
Heart Disease ◽  
General Population ◽  
Heart Transplantation ◽  
Heart Transplant ◽  
Congenital Heart ◽  
Medium Term ◽  
General Group

Introduction: Short and medium term outcome after heart transplantation has steadily improved over the last few decades. Outcomes for adult patients with congenital heart disease (ACHD) who undergo transplantation are generally considered to be less favorable. Hypothesis: We hypothesized that the development of heart teams that specialize in ACHD would lead to improved outcomes after transplantation in this population. Methods: We reviewed the records of all patients undergoing first heart transplant at a university center with a dedicated ACHD team over the last 10 years. Patients undergoing re-transplantation were excluded. We looked at short (30 days) and medium term (1 year) survival after heart transplantation in ACHD patients. Results: Between 1/1/05 and 6/10/15, 258 patients underwent heart transplantation. Of the 258 patients, 17 were re-transplants and were excluded. Of the remaining 241 patients, 12 were ACHD patients and 229 were transplanted for other diagnosis (general group). In the general group 184 of 212 (86.8%) patients were alive at 1 year (the remaining 17 did not have sufficient follow up to be included in the 1-year survival analysis). In the ACHD group 9 of 9 patients (100%) were alive at 1 year. The remaining 3 ACHD patients with insufficient follow up to be included in the 1-year survival analysis were still alive 2.5-9.5 months after transplant, such that all 12 ACHD patients survived at least 30 days and were discharged home after heart transplant. At the end of the study period 160 of 229 (70%) patients were still alive in the general group, compared to 8 of 12 (66.7%) in the ACHD group. Conclusions: Short and medium term survival after heart transplantation appears to be no worse for selected ACHD patients compared to the general population. Larger studies with longer follow up are needed to confirm our findings and clarify the intermediate and long-term outcomes of ACHD patients undergoing heart transplantation in the modern era.

Center volume and post-transplant survival among adults with congenital heart disease

2018 ◽  
Vol 37 (11) ◽  
pp. 1351-1360 ◽  
Author(s):  
Jonathan N. Menachem ◽  
Joann Lindenfeld ◽  
Kelly Schlendorf ◽  
Ashish S. Shah ◽  
David P. Bichell ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Congenital Heart ◽  
Transplant Survival ◽  
Post Transplant ◽  
Center Volume

Heart transplantation in adults with congenital heart disease; experience with 15 patients

2005 ◽  
Vol 53 (S 3) ◽  
Author(s):  
O Coskun ◽  
T Coskun ◽  
N Reiss ◽  
U Schulz ◽  
A Parsa ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Heart Transplantation ◽  
Congenital Heart ◽  
Disease Experience
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