scholarly journals Effects of antenatal depression screening and intervention among Chinese high‐risk pregnant women with medically defined complications: A randomized controlled trial

2018 ◽  
Vol 13 (5) ◽  
pp. 1090-1098 ◽  
Author(s):  
Ying Zhao ◽  
Michelle L. Munro‐Kramer ◽  
Shenxun Shi ◽  
Jing Wang ◽  
Qi Zhao
Keyword(s):  
Randomized Controlled Trial ◽  
High Risk ◽  
Pregnant Women ◽  
Controlled Trial ◽  
Antenatal Depression ◽  
Depression Screening ◽  
Randomized Controlled

scholarly journals Safety and pharmacokinetics of pravastatin used for the prevention of preeclampsia in high-risk pregnant women: a pilot randomized controlled trial

2016 ◽  
Vol 214 (6) ◽  
pp. 720.e1-720.e17 ◽  
Author(s):  
Maged M. Costantine ◽  
Kirsten Cleary ◽  
Mary F. Hebert ◽  
Mahmoud S. Ahmed ◽  
Linda M. Brown ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
High Risk ◽  
Pregnant Women ◽  
Controlled Trial ◽  
Randomized Controlled ◽  
Pilot Randomized Controlled Trial

scholarly journals Effect of Nurse Home Visits vs. Usual Care on Reducing Intimate Partner Violence in Young High-Risk Pregnant Women: A Randomized Controlled Trial

PLoS ONE ◽  
2013 ◽  
Vol 8 (10) ◽  
pp. e78185 ◽  
Author(s):  
Jamila Mejdoubi ◽  
Silvia C. C. M. van den Heijkant ◽  
Frank J. M. van Leerdam ◽  
Martijn W. Heymans ◽  
Remy A. Hirasing ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Intimate Partner Violence ◽  
High Risk ◽  
Usual Care ◽  
Pregnant Women ◽  
Partner Violence ◽  
Controlled Trial ◽  
Intimate Partner ◽  
Nurse Home ◽  
Randomized Controlled

scholarly journals Effect of Oral Prophylactic Measures on the Occurrence of Pre-Eclampsia (OP-PE) in High-Risk Pregnant Women: A Cluster Randomized Controlled Trial

2021 ◽  
Vol 4 (3) ◽  
pp. 61
Author(s):  
Aida Kanoute ◽  
Jocelyne Gare ◽  
Nicolas Meda ◽  
Stephane Viennot ◽  
Paul Tramini ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
High Risk ◽  
Pregnant Women ◽  
Oral Hygiene ◽  
Controlled Trial ◽  
Cluster Randomized Controlled Trial ◽  
Oral Microbiome ◽  
Randomized Controlled ◽  
Prophylactic Measures ◽  
Cluster Randomized

Pre-eclampsia (PE), a pregnancy-specific hypertensive disorder, characterized by the development of placental endothelial dysfunction, remains a major source of maternal and perinatal morbidity and mortality, especially in low- and middle-income settings. Periodontal disorders during pregnancy, and particularly periodontal pathogens, may be related to the risk of PE. Standard oral hygiene methods, based mainly on the joint use of toothbrushes and interdental brushes, reduce periodontal inflammatory risk and modulate the dysbiosis of the oral microbiome. The aim of this trial is to compare the PE outcomes in high-risk pregnant women receiving oral prophylactic measures to a control group. This trial is designed as a two-arm, parallel, cluster randomized controlled trial with the antenatal obstetric clinic as the unit of randomization and an allocation ratio of 1:1. The pregnant women will be included at 3 months of pregnancy and will be followed throughout the pregnancy. The primary outcome measure will be the incidence of PE from a baseline during the pregnancy. Secondary outcomes measures will include changes from the baseline in quantification of the pathogenic bacterial load of the interdental microbiota, the severity scores of periodontal indicators, and the incidence of adverse perinatal outcomes. This trial should demonstrate that the implementation of daily oral hygiene reduces oral dysbiosis, the incidence of periodontal disease, and the risk of PE.

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