Langerhans cell histiocytosis in an adult patient presenting with eruptions on the scalp and trunk accompanied by lytic lesions on the skull

2016 ◽  
Vol 55 (7) ◽  
pp. e408-e410 ◽  
Author(s):  
Masafumi Ishibashi ◽  
Eri Izumi
2015 ◽  
Vol 1 (3) ◽  
pp. e199-e203 ◽  
Author(s):  
Yan Bing ◽  
Guo Jing ◽  
Wang Chang-You ◽  
Wang Xue-Ming ◽  
Lu Chun-Xiu ◽  
...  

2017 ◽  
Vol 14 (2) ◽  
pp. 264-267 ◽  
Author(s):  
Ines Vielgut ◽  
Bernadette Liegl-Atzwanger ◽  
Gerhard Bratschitsch ◽  
Andreas Leithner ◽  
Roman Radl

2021 ◽  
Vol 40 ◽  
Author(s):  
Anis Mzabi ◽  
Maissa Thabet ◽  
Taghrid Tlili ◽  
Hend Zorgati ◽  
Jihed Anoun ◽  
...  

2019 ◽  
Vol 95 (4) ◽  
pp. 57-66
Author(s):  
A. E. Karamova ◽  
V. V. Chikin ◽  
L. F. Znamenskaya ◽  
M. A. Nefedova ◽  
V. A. Mikhina ◽  
...  

Aim: to present a clinical case of a rare dermatosis — Langerhans cell histiocytosis (LCH) in an adult patient.Materials and methods. A clinical and laboratory examination of a 64-year-old woman who had complained of rashes on the skin of the scalp, neck, trunk and lower extremities accompanied by itching was carried out. A histological study of skin biopsy samples from the lesion area, as well as an immunohistochemical study of Langerhans cell markers — langerin and S-100 protein — were performed.Results. Clinical manifestations of the disease, the presence of histiocytic infiltrate in the epidermis and dermis during the histological study and immunohistochemical detection of langerin infiltrate cells and S-100 protein were all consistent with the diagnosis of LCH. The therapy with methotrexate subcutaneously significantly improved the patient’s condition.Conclusion. Verification of the LCH diagnosis requires a histological study of skin biopsy samples and an immunohistochemical study of Langerhans cell markers. The efficacy of methotrexate in the treatment of this disease has been confirmed.


2018 ◽  
Vol 6 ◽  
pp. 232470961879294
Author(s):  
Vasileios Karamouzos ◽  
Christos Prokakis ◽  
Fotini Kosmopoulou ◽  
Evangelos Karanikolas ◽  
Christina Kalogeropoulou ◽  
...  

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