scholarly journals Adherence to antiretroviral therapy for human immunodeficiency virus/acquired immune deficiency syndrome among drug users: a systematic review

Addiction ◽  
2008 ◽  
Vol 103 (8) ◽  
pp. 1242-1257 ◽  
Author(s):  
Monica Malta ◽  
Steffanie A. Strathdee ◽  
Monica M. F. Magnanini ◽  
Francisco I. Bastos
Keyword(s):  
Immune Deficiency ◽  
Systematic Review ◽  
Human Immunodeficiency Virus ◽  
Antiretroviral Therapy ◽  
Drug Users ◽  
Immune Deficiency Syndrome ◽  
Acquired Immune Deficiency Syndrome ◽  
Deficiency Syndrome ◽  
Immunodeficiency Virus ◽  
Acquired Immune Deficiency

scholarly journals Metabolic abnormalities and overweight in HIV/AIDS persons-treated with antiretroviral therapy

2008 ◽  
Vol 21 (3) ◽  
pp. 277-283 ◽  
Author(s):  
Luísa Helena Maia Leite ◽  
Ana Beatriz de Mattos Marinho Sampaio
Keyword(s):  
Immune Deficiency ◽  
Human Immunodeficiency Virus ◽  
Antiretroviral Therapy ◽  
Immune Deficiency Syndrome ◽  
Acquired Immune Deficiency Syndrome ◽  
Deficiency Syndrome ◽  
Overweight And Obesity ◽  
Metabolic Complications ◽  
Immunodeficiency Virus ◽  
Acquired Immune Deficiency

OBJECTIVE: To describe the proportion of overweight among patients with human immunodeficiency virus/Acquired Immune Deficiency Syndrome and correlate overweight and highly active antiretroviral therapy with metabolic complications. METHODS: A cross-sectional study was conducted among human immunodeficiency virus/Acquired Immune Deficiency Syndrome outpatients undergoing nutritional therapy from 2000 to 2006 in a University Health Center. The sample consisted of 393 human immunodeficiency virus/Acquired Immune Deficiency Syndrome patients. Nutritional and medical records were used as a source of data on personal, clinical and biochemical information. Data analysis included descriptive statistics and the Chi-square test. RESULTS: Sixty-nine percent of the patients were males aging from 26 to 49 years. Overweight and obesity were identified in 49% of this population. The most important metabolic complications were low levels of high-density lipoprotein (70%) and high levels of triglycerides (48%) and cholesterol (40%). Higher body mass index was associated with higher lipid levels and more evidence of insulin resistance. CONCLUSION: This study demonstrated an important proportion of overweight and obesity among human immunodeficiency virus/Acquired Immune Deficiency Syndrome patients. These results suggest that nutritional interventions and lifestyle modifications may be useful strategies to decrease the cardiovascular risk in this population.

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