Effects of orexin and glucose microinjected into the hypothalamic paraventricular nucleus on gastric acid secretion in conscious rats

2011 ◽  
Vol 24 (2) ◽  
pp. e94-e102 ◽  
Author(s):  
N. Chaleek ◽  
M. Kermani ◽  
A. Eliassi ◽  
A. Haghparast
Keyword(s):  
Acid Secretion ◽  
Gastric Acid Secretion ◽  
Gastric Acid ◽  
Paraventricular Nucleus ◽  
Hypothalamic Paraventricular Nucleus ◽  
Conscious Rats

scholarly journals The mechanism of inhibitory action of secretin on gastric acid secretion in conscious rats.

1995 ◽  
Vol 488 (2) ◽  
pp. 501-508 ◽  
Author(s):  
K Shimizu ◽  
P Li ◽  
K Y Lee ◽  
T M Chang ◽  
W Y Chey
Keyword(s):  
Acid Secretion ◽  
Gastric Acid Secretion ◽  
Gastric Acid ◽  
Inhibitory Action ◽  
Conscious Rats

Electrical stimulation of the medial amygdala facilitates gastric acid secretion in conscious rats

1990 ◽  
Vol 524 (2) ◽  
pp. 208-212 ◽  
Author(s):  
Myung Suk Kim ◽  
Yang Hyeok Jo ◽  
Shin Hee Yoon ◽  
Sang June Hahn ◽  
Duck Joo Rhie ◽  
...  
Keyword(s):  
Electrical Stimulation ◽  
Acid Secretion ◽  
Gastric Acid Secretion ◽  
Gastric Acid ◽  
Medial Amygdala ◽  
Conscious Rats ◽  
Stimulation Of

Evidence for a Central Inhibitory Role of Growth Hormone Secretagogues and Ghrelin on Gastric Acid Secretion in Conscious Rats

2002 ◽  
Vol 75 (2) ◽  
pp. 92-97 ◽  
Author(s):  
V. Sibilia ◽  
F. Pagani ◽  
F. Guidobono ◽  
V. Locatelli ◽  
A. Torsello ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Acid Secretion ◽  
Gastric Acid Secretion ◽  
Gastric Acid ◽  
Growth Hormone Secretagogues ◽  
Conscious Rats ◽  
Inhibitory Role

scholarly journals A Novel Method of Measurement of Gastric Acid Secretion in Intact and Conscious Rats

1984 ◽  
Vol 104 (10) ◽  
pp. 1090-1094 ◽  
Author(s):  
MASAKI HAGIWARA ◽  
HIROSHI WATANABE ◽  
KEIKO KAWATA ◽  
KAZUO WATANABE
Keyword(s):  
Acid Secretion ◽  
Gastric Acid Secretion ◽  
Gastric Acid ◽  
Conscious Rats ◽  
Novel Method ◽  
Method Of Measurement

Glycine-extended gastrin potentiates gastrin-stimulated gastric acid secretion in rats

1996 ◽  
Vol 270 (1) ◽  
pp. G220-G224 ◽  
Author(s):  
S. Higashide ◽  
G. Gomez ◽  
G. H. Greeley ◽  
C. M. Townsend ◽  
J. C. Thompson
Keyword(s):  
Acid Secretion ◽  
Gastric Acid Secretion ◽  
Gastric Acid ◽  
Intravenous Administration ◽  
Biological Effect ◽  
Acid Output ◽  
Intermediate Form ◽  
Bolus Administration ◽  
Conscious Rats

The purpose of this study was to examine whether an intermediate form of amidated gastrin, glycine-extended gastrin (Gly-G), can stimulate gastric acid secretion in conscious rats prepared with gastric fistulas. Intravenous administration of Gly-G (20 nmol.kg-1.h-1) alone for 2 h did not stimulate gastric acid secretion; however, administration of Gly-G (20 nmol.kg-1.h-1) in combination with a bolus administration of gastrin (9.5 nmol/kg) potentiated acid secretion significantly. Gastric acid secretion in response to gastrin alone and gastrin plus Gly-G (2 nmol.kg-1.h-1) was 109.1 +/- 21.6 and 170.1 +/- 27.7 mueq.kg-1.h-1, respectively (P < 0.05). Gastric acid secretion in response to gastrin alone and gastrin plus Gly-G (20 nmol.kg-1.h-1) was 84.8 +/- 17.5 and 164.1 +/- 29.3 mueq.kg-1.h-1, respectively (P < 0.05). Intravenous administration of Gly-G (20 nmol.kg-1.h-1) failed to increase histamine (1 mg/kg)-stimulated acid output. These results demonstrate that Gly-G can selectively potentiate the stimulatory effect of gastrin on acid secretion in rats and that the unprocessed form of gastrin, Gly-G, can exert a biological effect in the stomach.

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