Effects of Alkyl Alcohols and Related Chemicals on Rat Liver Structure and Function

1991 ◽  
Vol 41 (6) ◽  
pp. 405-413
Author(s):  
Takashi Wakabayashi ◽  
Kayo Adachi ◽  
Jerzy Popinigis
1991 ◽  
Vol 41 (6) ◽  
pp. 414-427
Author(s):  
Kayo Adachi ◽  
Takashi Wakabayashi ◽  
Jerzy Popinigis

1977 ◽  
Vol 168 (1) ◽  
pp. 1-8 ◽  
Author(s):  
J C Ramsey ◽  
W J Steele

Free loosely bound and tightly bound polyribosomes were separated from rat liver homogenate by salt extraction followed by differential centrifugation, and several of their structural and functional properties were compared to resolve the existence of loosely bound polyribosomes and verify the specificity of the separation. The free and loosely bound polyribosomes have similar sedimentation profiles and polyribosome contents, their subunit proteins have similar electrophoretic patterns and their products of protein synthesis in vitro show a close correspondence in size and amounts synthesized. In contrast, the tightly bound polyribosomes have different properties from those of the free and loosely bound polyribosomes; their average size is significantly smaller; their polyribosome content is higher; their 60 S-subunit proteins lack two components and contain four or more components not found elsewhere; their products of protein synthesis in vitro differ in size and amounts synthesized. These observations show that rat liver membranes entrap a large fraction of the free polyribosomes at low salt concentrations and that these polyribosomes are similar to those of the free-polyribosome fraction and are different from those of the tightly bound polyribosome fraction in size, structure and function.


2018 ◽  
Vol 34 (2) ◽  
pp. 111-116 ◽  
Author(s):  
Tamer Simsek ◽  
◽  
Omer Faik Ersoy ◽  
Zeki Ozsoy ◽  
Erdinc Yenidogan ◽  
...  

2019 ◽  
Vol 14 (4) ◽  
pp. 15-20 ◽  
Author(s):  
G.V. Volynets ◽  
◽  
A.V. Nikitin ◽  
T.A. Skvortsova ◽  
A.I. Khavkin ◽  
...  

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