Glomerular sequence of events concerning monocyte/ macrophage accumulation and ICAM-1 expression during experimental serum sickness nephritis in the rat2

1997 ◽  
Vol 47 (4) ◽  
pp. 238-249 ◽  
Author(s):  
Xiuying Yang
Keyword(s):  
Serum Sickness ◽  
Sequence Of Events ◽  
Macrophage Accumulation ◽  
Serum Sickness Nephritis

Anti-nephritic effects of prostaglandin E1 on serum sickness nephritis in rat

Ensho ◽  
1982 ◽  
Vol 2 (4) ◽  
pp. 317-318
Author(s):  
Tadashi Nagamatsu ◽  
Yoshio Suzuki ◽  
Kouji Ikuta ◽  
Shigehisa Aoki
Keyword(s):  
Prostaglandin E1 ◽  
Serum Sickness ◽  
Serum Sickness Nephritis

scholarly journals The role of monocytes in serum sickness nephritis.

1979 ◽  
Vol 150 (3) ◽  
pp. 413-425 ◽  
Author(s):  
L G Hunsicker ◽  
T P Shearer ◽  
S B Plattner ◽  
D Weisenburger
Keyword(s):  
Electron Microscopy ◽  
Bovine Serum Albumin ◽  
Bovine Serum ◽  
The Other ◽  
Serum Sickness ◽  
Nonspecific Esterase ◽  
Immune Clearance ◽  
Rate Of Increase ◽  
Serum Sickness Nephritis

We have investigated the pathogenesis of glomerular hypercellularity seen in acute serum sickness nephritis induced in rabbits with bovine serum albumin (BSA). The increase in cellularity began with the first stages of immune clearance of BSA, with a peak cellularity occuring at the time of onset of proteinuria. Although there was a significant increase in the fraction of glomerular cells incorporating [3H]thymidine, first seen at the onset of proteinuria, this increase occurred too late and was too small to explain the observed rate of increase in glomerular cellularity. On the other hand, a striking monocytic infiltration of the glomeruli was documented by electron microscopy and by staining for nonspecific esterase. This monocytic infiltration paralleled the observed course of glomerular hypercellularity and was quantitatively sufficient to explain the total increase seen. It appears, therefore, that glomerular hypercellularity seen in this model is principally a result of monocyte infiltration.

Conversion of glomerular histology from a mesangiopathic to a membranopathic pattern in serum sickness nephritis with prolonged sensitization

1995 ◽  
Vol 45 (1) ◽  
pp. 26-33 ◽  
Author(s):  
Xiuying Yang ◽  
Koh Nakazawa ◽  
Masahiro Katoh ◽  
Nabuo Itoh ◽  
Hidekazu Shigematsu
Keyword(s):  
Serum Sickness ◽  
Serum Sickness Nephritis
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