Reference Values of Tissue Doppler Imaging and Pulsed Doppler Echocardiography for Analysis of Left Ventricular Diastolic Function in Healthy Adults

Aim of study: To study changes of left ventricular diastolic function and morphology in adroid obesity patients by standard doppler echocardiography and tissue doppler imaging. In that, evaluate the role of Tissue Doppler Imaging(TDI) in studying the left ventricular diastolic function. Patients and methods: We studied 30 obese patients (12 men have waist circumference ≥90cm and 18 women have waist circumference ≥80 cm), mean age 49.33±7.16 years , non hypertension and non diabetic, by conventional doppler echocardiography and tissue doppler imaging. Results: Mean BMI of obese patients: 25,35±2,87kg/m2. Waist circumference: 91,03±6,29cm. Left ventricular end- diastolic diameter: 45,9±4,05mm. Left ventricular mass: 143,47±35,56g. Left ventricular mass index: 85,69±19,55g/m2. Left atrial diameter: 36,34±4,33mm. The early diastolic wave of the transmitral flow velocity(E): 75,2±17,5 cm/s; the atrial systolic wave of the transmitral flow velocity: 76,2±16,5cm/s; the ratio of early diastolic wave to atrial systolic wave of the transmitral flow velocity: 0,99±0,29. The early diastolic wave of mitral annu-lus using pulsed TDI(Em): 12,1±3,3cm/s. The atrial systolic wave of mitral annu-lus using pulsed TDI(Am): 12,7±2,9cm/s. E to Em wave ratio: 6,76±2,19. Conclusion: In adroid obesity patients, the morphology of diastolic left ventricular changes earlier than the one’s function. Key word: Left ventricular function; Obesity; Tissue Doppler Echocardiography

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Reference values of left ventricular diastolic function accessed by conventional and Doppler echocardiography in healthy Angolans: effect of age and gender

10.22541/au.161169022.23653445/v1 ◽

2021 ◽

Author(s):

Humberto Morais ◽

Ana Feijão ◽

Savarino Victória Pereira

Keyword(s):

Diastolic Function ◽

Wave Velocity ◽

Reference Values ◽

Doppler Echocardiography ◽

Left Ventricular Diastolic Function ◽

Tissue Doppler ◽

Left Ventricular ◽

Tissue Doppler Echocardiography ◽

Ventricular Diastolic Function ◽

And Gender

Introduction: Studies about the reference values of the conventional and tissue Doppler echocardiography in African populations are limited. Objectives: The aim of this study is to evaluate the effect of aging and gender in left ventricular diastolic function assessed by conventional and tissue Doppler echocardiography in healthy Angolans. Methods: Cross-sectional study performed involving healthy participants aged between 18 and 85 years, attending in a diagnostic center in Luanda, Angola. Two-dimensional transthoracic echocardiography and Doppler study were performed according to the Guidelines of the American Society of Echocardiography and the European Association of Cardiovascular Imaging. Results: A total of 103 men (47.5%) (mean age: 39,5±10,8) and 114 women (52,5%) (mean age: 43,0±12,5 years) were included. Compared to men, women were older (p=0,025) and showed significantly smaller body surface area (p<0,001). Mitral E velocity, and E/e’ ratio were significantly higher in women compared to men. While, DT of mitral E velocity was longer in men compared to women (p=0,041), E wave velocity and E/A ratio show a negative significant correlation with increasing age (r -0,33; P ≤ 0.001 and r -0,48; P ≤ 0.001, respectively). Conversely, A wave velocity shows a significant positive correlation with age (r 0,47; P < 0.001). Average e′ wave velocity shows a significant negative correlation with aging (r -0,40; P ≤ 0.0001). Conclusions: In healthy Angolan adult population, the parameters of left ventricular diastolic function deteriorated with age reflecting a normal aging process. This must be taken into account when assessing diastolic function at different age’s categories.

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