A double-blind study of zimelidine, a serotonin uptake inhibitor, and desipramine, a noradrenaline uptake inhibitor, in endogenous depression

1982 ◽  
Vol 66 (1) ◽  
pp. 66-82 ◽  
Author(s):  
A. Åberg-Wistedt ◽  
S. B. Ross ◽  
K.-G. Jostell ◽  
B. Sjöquist
1987 ◽  
Vol 151 (3) ◽  
pp. 337-340 ◽  
Author(s):  
J. P. R. Young ◽  
A. Coleman ◽  
M. H. Lader

Fluoxetine, a selective serotonin uptake inhibitor (mean dose 73 mg each morning) was compared with amitriptyline (mean dose 122 mg at night) in a double-blind study of 64 depressed out-patients. Fifty patients completed the 6-week trial. The drugs did not differ with respect to psychiatrists' ratings, but amitriptyline was slightly superior with respect to patients' ratings. The amitriptyline-treated group had complaints of dry mouth and dizziness on standing; the fluoxetine-treated group of sleep disturbances, nausea, and headaches.


1979 ◽  
Vol 33 (6) ◽  
pp. 455-460 ◽  
Author(s):  
S. Bøjholm ◽  
C. Børup ◽  
J. Kvist ◽  
I-M. Petersen ◽  
P. Le Fevre Honoré

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