ANAPHYLAXIS AND RED CELL SURVIVAL STUDIES IN A CHILD WITH INSULIN-RESISTANT DIABETES MELLITUS

1971 ◽  
Vol 60 (6) ◽  
pp. 647-652 ◽  
Author(s):  
E. J. TOMSOVIC ◽  
W. PAGE FAULK ◽  
H. H. FUDENBERG
Keyword(s):  
Diabetes Mellitus ◽  
Cell Survival ◽  
Red Cell ◽  
Insulin Resistant ◽  
Red Cell Survival ◽  
Survival Studies

Splenomegaly with Hypersplenism in Sickle Cell Anemia Treated by Radiation—Case Report

PEDIATRICS ◽  
1971 ◽  
Vol 48 (3) ◽  
pp. 457-458
Author(s):  
Annemarie Sommer ◽  
Stella B. Kontras
Keyword(s):  
Cell Survival ◽  
Sickle Cell ◽  
Sickle Cell Anemia ◽  
Marked Improvement ◽  
Costal Margin ◽  
Red Cell ◽  
Older Children ◽  
Before And After ◽  
Red Cell Survival ◽  
Survival Studies

The incidence of splenomegaly in sickle cell anemia (defined as a spleen easily palpated below the costal margin in quiet respiration) appears to be around 10% after 10 years of age. Persistent splenomegaly in older children is rare and frequently is associated with hypersplenism. Splenectomy has been the treatment of choice in several reported cases based on red cell survival studies before and after splenectomy.1-3 Removal of the spleen has been found to be associated with marked improvement of previously very shortened red cell survival. We want to report the case of a 12-year-old boy with sickle cell anemia, splenomegaly, and sickle cell heart disease who was treated by radiation therapy for his enlarged spleen because of hypersplenism.

scholarly journals Glycosylated hemoglobins (GHb): an index of red cell survival

Blood ◽  
1982 ◽  
Vol 59 (6) ◽  
pp. 1348-1350 ◽  
Author(s):  
S Panzer ◽  
G Kronik ◽  
K Lechner ◽  
P Bettelheim ◽  
E Neumann ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Cell Survival ◽  
Hemolytic Anemia ◽  
Screening Test ◽  
Red Cell ◽  
Red Cell Survival ◽  
Normal Controls

Abstract Levels of glycosylated hemoglobins (GHb) are significantly (p less than 0.0005) lower in patients with hemolytic anemia (n = 20; mean = 3.9% +/- 0.1% SD GHb of total Hb) compared to patients with nonhemolytic anemia (n = 20; mean = 7.0% +/- 0.7% GHb) and normal controls (n = 30; mean = 6.7% +/- 0.7% GHb). A curvilinear correlation between GHb and red cell survival is demonstrable (n = 20;r2 = 0.88; p less than 0.001). Determination of GHb may be useful as a screening test for hemolytic anemia and for the evaluation of the degree of hemolysis, provided that diabetes mellitus can be excluded.

Direct in vivo biotinylation of erythrocytes as an assay for red cell survival studies

1991 ◽  
Vol 63 (4) ◽  
pp. 214-217 ◽  
Author(s):  
G. Hoffmann-Fezer ◽  
H. Maschke ◽  
H. J. Zeitler ◽  
P. Gais ◽  
W. Heger ◽  
...  
Keyword(s):  
Cell Survival ◽  
Red Cell ◽  
Red Cell Survival ◽  
Survival Studies

Elution Correction in51Cr Red Cell Survival Studies

1974 ◽  
Vol 26 (2) ◽  
pp. 179-184 ◽  
Author(s):  
S. A. Bentley ◽  
H. I. Glass ◽  
S. M. Lewis ◽  
L. Szur
Keyword(s):  
Cell Survival ◽  
Red Cell ◽  
Red Cell Survival ◽  
Survival Studies

scholarly journals Glycosylated hemoglobins (GHb): an index of red cell survival

Blood ◽  
1982 ◽  
Vol 59 (6) ◽  
pp. 1348-1350 ◽  
Author(s):  
S Panzer ◽  
G Kronik ◽  
K Lechner ◽  
P Bettelheim ◽  
E Neumann ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Cell Survival ◽  
Hemolytic Anemia ◽  
Screening Test ◽  
Red Cell ◽  
Red Cell Survival ◽  
Normal Controls

Levels of glycosylated hemoglobins (GHb) are significantly (p less than 0.0005) lower in patients with hemolytic anemia (n = 20; mean = 3.9% +/- 0.1% SD GHb of total Hb) compared to patients with nonhemolytic anemia (n = 20; mean = 7.0% +/- 0.7% GHb) and normal controls (n = 30; mean = 6.7% +/- 0.7% GHb). A curvilinear correlation between GHb and red cell survival is demonstrable (n = 20;r2 = 0.88; p less than 0.001). Determination of GHb may be useful as a screening test for hemolytic anemia and for the evaluation of the degree of hemolysis, provided that diabetes mellitus can be excluded.

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