Peptide YY/Neuropeptide Y Receptors in Small Intestine.

1990 ◽  
Vol 611 (1 Central and P) ◽  
pp. 343-346 ◽  
Author(s):  
T. VOISIN ◽  
C. ROUYER-FESSARD ◽  
M. LABURTHE
2019 ◽  
Vol 2019 (4) ◽  
Author(s):  
Annette Beck-Sickinger ◽  
William F. Colmers ◽  
Helen M. Cox ◽  
Henri N. Doods ◽  
Herbert Herzog ◽  
...  

Neuropeptide Y (NPY) receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Neuropeptide Y Receptors [156]) are activated by the endogenous peptides neuropeptide Y, neuropeptide Y-(3-36), peptide YY, PYY-(3-36) and pancreatic polypeptide (PP). The receptor originally identified as the Y3 receptor has been identified as the CXCR4 chemokine recepter (originally named LESTR, [137]). The y6 receptor is a functional gene product in mouse, absent in rat, but contains a frame-shift mutation in primates producing a truncated non-functional gene [83]. Many of the agonists exhibit differing degrees of selectivity dependent on the species examined. For example, the potency of PP is greater at the rat Y4 receptor than at the human receptor [61]. In addition, many agonists lack selectivity for individual subtypes, but can exhibit comparable potency against pairs of NPY receptor subtypes, or have not been examined for activity at all subtypes. [125I]-PYY or [125I]-NPY can be used to label Y1, Y2, Y5 and y6 subtypes non-selectively, while [125I][cPP(1-7), NPY(19-23), Ala31, Aib32, Gln34]hPP may be used to label Y5 receptors preferentially (note that cPP denotes chicken peptide sequence and hPP is the human sequence).


1994 ◽  
Vol 269 (2) ◽  
pp. 127-132 ◽  
Author(s):  
Daniel Grandt ◽  
Friedhelm Feth ◽  
Wolfgang Rascher ◽  
Joseph R. Reeve ◽  
Eberhard Schlicker ◽  
...  

1991 ◽  
Vol 203 (2) ◽  
pp. 165-171 ◽  
Author(s):  
Agnes Modin ◽  
John Pernow ◽  
Jan M. Lundberg

1990 ◽  
Vol 611 (1 Central and P) ◽  
pp. 58-72 ◽  
Author(s):  
RÉMI QUIRION ◽  
JEAN-CLAUDE MARTEL ◽  
YVAN DUMONT ◽  
ALAIN CADIEUX ◽  
FRANCOIS JOLICOEUR ◽  
...  

1987 ◽  
Vol 74 (2) ◽  
pp. 237-242 ◽  
Author(s):  
Anita Westlind-Danielsson ◽  
Anders Undén ◽  
Janis Abens ◽  
Siv Andell ◽  
Tamas Bartfai

Peptides ◽  
1992 ◽  
pp. 152-153
Author(s):  
J. J. Leban ◽  
D. Heyer ◽  
J. Matthews ◽  
A. J. Daniels

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