Relation of Level of Protein and Pteroylglutamic Acid to Growth and Anemia in the Rat

2009 ◽  
Vol 6 (11) ◽  
pp. 336-336
Keyword(s):  
1947 ◽  
Vol 168 (2) ◽  
pp. 705-710
Author(s):  
B.L. Hutchings ◽  
E.L.R. Stokstad ◽  
J.H. Boothe ◽  
J.H. Mowat ◽  
C.W. Waller ◽  
...  

1946 ◽  
Vol 165 (1) ◽  
pp. 371-375
Author(s):  
J.J. Oleson ◽  
B.L. Hutchings ◽  
N.H. Sloane
Keyword(s):  

1947 ◽  
Vol 170 (1) ◽  
pp. 323-328
Author(s):  
B.L. Hutchings ◽  
J.H. Mowat ◽  
J.J. Oleson ◽  
E.L.R. Stokstad ◽  
J.H. Boothe ◽  
...  
Keyword(s):  

1977 ◽  
Vol 53 (1) ◽  
pp. 75-80
Author(s):  
H. Taguchi ◽  
Z. Abdul-Cader ◽  
J. Perry ◽  
E. H. Reynolds ◽  
I. Chanarin

1. The isolated choroid plexus of the rabbit takes up 5-methyltetrahydrofolate from the incubation medium. 2. Other folate analogues (pteroylglutamic acid, methotrexate, 5-formyltetrahydrofolate = folinic acid) inhibited the uptake of 5-methyltetrahydrofolate. 3. The uptake of 5-methyltetrahydrofolate was inhibited by low temperature, anaerobic conditions and dinitrophenol. 4. The anticonvulsant drugs, diphenylhydantoin and phenobarbital, had no effect on 5-methyltetrahydrofolate uptake. 5. The inhibitory effect of pteroylglutamic acid on the uptake of 5-methyltetrahydrofolate by the choroid plexus may explain the effect of long-term folic acid therapy in aggravating vitamin B12 neuropathy in pernicious anaemia.


1963 ◽  
Vol 112 (2) ◽  
pp. 486-489 ◽  
Author(s):  
N. Grossowicz ◽  
M. Rachmilewitz ◽  
G. Izak

Sign in / Sign up

Export Citation Format

Share Document