Comparison of the morphological characteristics of the glaucomatous optic nerve damage in different types of open angle glaucoma

2010 ◽  
Vol 88 ◽  
pp. 0-0
Author(s):  
G BOLIVAR ◽  
M CASTEJON ◽  
E ARRANZ-MARQUEZ ◽  
J AREVALO-SERRANO ◽  
MA TEUS
Keyword(s):  
Optic Nerve ◽  
Open Angle Glaucoma ◽  
Morphological Characteristics ◽  
Nerve Damage ◽  
Open Angle ◽  
Optic Nerve Damage ◽  
Different Types

Visual evoked potentials (VEP) studies in primary open glaucoma

2021 ◽  
Vol 19 (3) ◽  
pp. 28-31
Author(s):  
Bhagya V ◽  
Keyword(s):  
Optic Nerve ◽  
Visual Evoked Potential ◽  
Evoked Potential ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Visual Pathway ◽  
Nerve Damage ◽  
Open Angle ◽  
Optic Nerve Damage ◽  
Visual Evoked

Background: With increasing prevalance of primary open angle glaucoma and optic nerve damage as a consequence of this, there is a need for early diagnosis and prevention of optic nerve damage. VEP, the potential recorded from the occipital region in response to the visual stimuli can be used for early detection of the primary open angle glaucoma. Visual evoked potential (VEP) is a non invasive method to assess the visual pathway. The present study was done to evaluate the impact of primary open angle glaucoma on central nervous system particularly, visual pathway. Methods: 30 primary open angle glaucoma patients attending outpatient department of ophthalmology department, SS hospital, Davanagere and 30 age matched controls selected randomly from general population were subjected to Visual evoked potential. Parameters for VEP such as latencies of waves N70, P100, and N155 peak-to-peak amplitudes of waves N70-P100 and P100-N155 were assessed and analyzed by using unpaired student-T test for comparison between cases and controls. Results: The present study observed that the there was a statistically significant increase in P100 latency in cases compared to the controls. And also there was a statistically significant decrease in N70 and P100 amplitude in cases compared to the controls. Conclusion: The present study correlates with earlier findings that visual pathway gets involved in primary open angle glaucoma even before the development of neuropathy which can be detected using VEP. Meticulous follow-up is a must to prevent the complications of primary open angle glaucoma, so that further damage can be prevented.

Predictive Factors for Progressive Optic Nerve Damage in Various Types of Chronic Open-angle Glaucoma

2005 ◽  
Vol 139 (6) ◽  
pp. 999-1009 ◽  
Author(s):  
Peter Martus ◽  
Andrea Stroux ◽  
Wido M. Budde ◽  
Christian Y. Mardin ◽  
Matthias Korth ◽  
...  
Keyword(s):  
Optic Nerve ◽  
Predictive Factors ◽  
Open Angle Glaucoma ◽  
Nerve Damage ◽  
Open Angle ◽  
Optic Nerve Damage ◽  
Chronic Open Angle Glaucoma

scholarly journals Pearls for Correct Assessment of Optic Disc at Glaucoma Diagnosis

2017 ◽  
Vol 10 (02) ◽  
pp. 104
Author(s):  
Burak Turgut ◽  
Keyword(s):  
Optic Nerve ◽  
Visual Field ◽  
Optic Disc ◽  
Open Angle Glaucoma ◽  
Visual Field Defects ◽  
Open Angle ◽  
Correct Evaluation ◽  
Optic Nerve Damage ◽  
Glaucoma Diagnosis ◽  
Field Defects

The correct evaluation of the optic disc, and related structures in ophthalmoscopy, is critical for the diagnosis of open angle glaucoma because usually glaucomatous optic nerve damage firstly occurs in the optic disc before detectable visual field defects become apparent; however, some studies have demonstrated that visual field defects can also be found without any glaucomatous changes in the optic disc. The purpose of this review is to provide a guide to clinicians for the evaluation of the optic disc in glaucoma suspects and patients. This guide can facilitate the diagnosis and exclusion of glaucoma in these subjects.

scholarly journals Cochlin and glaucoma: A mini-review

2005 ◽  
Vol 22 (5) ◽  
pp. 605-613 ◽  
Author(s):  
SANJOY K. BHATTACHARYA ◽  
NEAL S. PEACHEY ◽  
JOHN W. CRABB
Keyword(s):  
Optic Nerve ◽  
Collagen Type ◽  
Late Onset ◽  
Open Angle Glaucoma ◽  
Nerve Damage ◽  
Contributory Factor ◽  
Retinal Ganglion ◽  
Cell Degeneration ◽  
Future Studies ◽  
Optic Nerve Damage

Primary open angle glaucoma (POAG) is a leading cause of late onset, progressive, irreversible blindness and, although its etiology is poorly understood, elevated intraocular pressure (IOP) often appears to be a contributory factor. Proteomic and Western analyses of trabecular meshwork (TM) from patients with POAG and age-matched controls originally implicated cochlin as possibly contributing to glaucoma pathogenesis. Cochlin deposits were subsequently detected in glaucomatous but not in control TM and older glaucomatous TM was found to contain higher levels of cochlin and significantly lower amounts of collagen type II. More recently, similar results were reported in DBA/2J mice, which at older ages develop elevated IOP, retinal ganglion cell degeneration, and optic nerve damage. Notably, cochlin was absent in TM from C57BL/6J, CD1, and BALBc/ByJ mice, which do not exhibit elevated IOP or glaucoma. Cochlin was found in the TM of very young DBA/2J mice, prior to elevated IOP, suggesting that over time the protein may contribute to the events leading to increased IOP and optic nerve damage. Here we review these findings and describe how future studies in DBA/2J mice can help resolve whether cochlin plays a causal role in mechanisms of POAG and elevated IOP.

scholarly journals Current Approach in the Diagnosis and Management of Uveitic Glaucoma

2015 ◽  
Vol 2015 ◽  
pp. 1-13 ◽  
Author(s):  
Francisco J. Muñoz-Negrete ◽  
Javier Moreno-Montañés ◽  
Paula Hernández-Martínez ◽  
Gema Rebolleda
Keyword(s):  
Optic Nerve ◽  
Open Angle Glaucoma ◽  
Interdisciplinary Approach ◽  
Glaucoma Surgery ◽  
Current Approach ◽  
Nerve Damage ◽  
Uveitic Glaucoma ◽  
Optic Nerve Damage ◽  
Iop Elevation ◽  
Adequate Management

Uveitic glaucoma (UG) typically is associated with very high intraocular pressure (IOP) and more intense optic nerve damage than other glaucoma types. This secondary glaucoma requires an early diagnosis and adequate management of both uveitis and glaucoma. It is mandatory to identify the mechanisms of IOP elevation that in many eyes have multiple combined mechanisms. Management of these patients commonly requires an interdisciplinary approach that includes a glaucoma specialist and rheumatologist to control the inflammation and IOP. Glaucoma surgery is required early in these patients due to the high IOP usually present and is less successful than in primary open-angle glaucoma. Recurrent uveitic episodes, multiple mechanism, and the complications associated with uveitis make surgical management of UG challenging. In this review, the management and treatment of UG are updated to clarify the pathogenesis and prevent optic nerve damage.

Sign in / Sign up

Export Citation Format

Share Document