Aldose reductase inhibitor ranirestat significantly improves nerve conduction velocity in diabetic polyneuropathy: A randomized double-blind placebo-controlled study in Japan

Kenji Sekiguchi; Nobuo Kohara; Masayuki Baba; Tetsuo Komori; Yutaka Naito; Tomihiro Imai; Jo Satoh; Yasuyuki Yamaguchi; Tatsuto Hamatani;

doi:10.1111/jdi.12890

Aldose reductase inhibitor ranirestat significantly improves nerve conduction velocity in diabetic polyneuropathy: A randomized double-blind placebo-controlled study in Japan

Journal of Diabetes Investigation ◽

10.1111/jdi.12890 ◽

2018 ◽

Vol 10 (2) ◽

pp. 466-474 ◽

Cited By ~ 8

Author(s):

Kenji Sekiguchi ◽

Nobuo Kohara ◽

Masayuki Baba ◽

Tetsuo Komori ◽

Yutaka Naito ◽

...

Keyword(s):

Conduction Velocity ◽

Aldose Reductase ◽

Nerve Conduction ◽

Reductase Inhibitor ◽

Nerve Conduction Velocity ◽

Diabetic Polyneuropathy ◽

Aldose Reductase Inhibitor ◽

Controlled Study ◽

Double Blind ◽

Double Blind Placebo

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The effects of Zenarestat, an aldose reductase inhibitor, on the nerve conduction velocity in Zucker diabetic fatty rats

The Japanese Journal of Pharmacology ◽

10.1016/s0021-5198(19)40525-8 ◽

1998 ◽

Vol 76 ◽

pp. 101

Author(s):

Yukinori Shimoshige ◽

Kyoko Ikuma ◽

Tadashi Yamamoto ◽

Shoji Takakura ◽

Ikuo Kawamura ◽

...

Keyword(s):

Conduction Velocity ◽

Aldose Reductase ◽

Nerve Conduction ◽

Reductase Inhibitor ◽

Nerve Conduction Velocity ◽

Aldose Reductase Inhibitor ◽

Zucker Diabetic Fatty Rats

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Improvement of nerve conduction velocity in mutant diabetic mice by aldose reductase inhibitor without affecting nerve myo-inositol content.

Chemical and Pharmaceutical Bulletin ◽

10.1248/cpb.37.1581 ◽

1989 ◽

Vol 37 (6) ◽

pp. 1581-1582 ◽

Cited By ~ 10

Author(s):

Ichitomo MIWA ◽

Motoya KANBARA ◽

Jun OKUDA

Keyword(s):

Conduction Velocity ◽

Aldose Reductase ◽

Nerve Conduction ◽

Reductase Inhibitor ◽

Nerve Conduction Velocity ◽

Aldose Reductase Inhibitor ◽

Diabetic Mice

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Prevention of defects of axonal transport and nerve conduction velocity by oral administration of myo-inositol or an aldose reductase inhibitor in streptozotocin-diabetic rats

Diabetologia ◽

10.1007/bf00282524 ◽

1983 ◽

Vol 25 (5) ◽

pp. 433-438 ◽

Cited By ~ 164

Author(s):

J. H. Mayer ◽

D. R. Tomlinson

Keyword(s):

Oral Administration ◽

Axonal Transport ◽

Conduction Velocity ◽

Aldose Reductase ◽

Nerve Conduction ◽

Reductase Inhibitor ◽

Nerve Conduction Velocity ◽

Diabetic Rats ◽

Aldose Reductase Inhibitor ◽

Streptozotocin Diabetic Rats

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160: Effects of an Aldose Reductase Inhibitor on Nerve Conduction Velocity and Bladder Function in Streptozotocin (STZ)-Treated Female Rats

The Journal of Urology ◽

10.1016/s0022-5347(18)34425-2 ◽

2005 ◽

Vol 173 (4S) ◽

pp. 43-43

Author(s):

Elena G. Zotova ◽

George J. Christ ◽

Weixin Zhao ◽

Tar Moses ◽

Srini D. Kuppam ◽

...

Keyword(s):

Conduction Velocity ◽

Aldose Reductase ◽

Nerve Conduction ◽

Reductase Inhibitor ◽

Nerve Conduction Velocity ◽

Aldose Reductase Inhibitor ◽

Female Rats ◽

Bladder Function

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Effects of fidarestat, an aldose reductase inhibitor, on nerve conduction velocity and bladder function in streptozotocin-treated female rats

Journal of Diabetes and its Complications ◽

10.1016/j.jdiacomp.2005.10.001 ◽

2007 ◽

Vol 21 (3) ◽

pp. 187-195 ◽

Cited By ~ 18

Author(s):

Elena G. Zotova ◽

George J. Christ ◽

Weixin Zhao ◽

Moses Tar ◽

Srini D. Kuppam ◽

...

Keyword(s):

Conduction Velocity ◽

Aldose Reductase ◽

Nerve Conduction ◽

Reductase Inhibitor ◽

Nerve Conduction Velocity ◽

Aldose Reductase Inhibitor ◽

Female Rats ◽

Bladder Function

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Reversal of defective peripheral nerve conduction velocity, nutritive endoneurial blood flow, and oxygenation by a novel aldose reductase inhibitor, WAY-121,509, in streptozotocin-induced diabetic rats

Journal of Diabetes and its Complications ◽

10.1016/1056-8727(94)00076-x ◽

1996 ◽

Vol 10 (1) ◽

pp. 43-53 ◽

Cited By ~ 20

Author(s):

Norman E. Cameron ◽

Mary A. Cotter ◽

Kevin C. Dines ◽

Thomas C. Hohman

Keyword(s):

Blood Flow ◽

Peripheral Nerve ◽

Conduction Velocity ◽

Aldose Reductase ◽

Nerve Conduction ◽

Reductase Inhibitor ◽

Nerve Conduction Velocity ◽

Diabetic Rats ◽

Aldose Reductase Inhibitor ◽

Endoneurial Blood Flow

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Prevention and reversal of defective axonal transport and motor nerve conduction velocity in rats with experimental diabetes by treatment with the aldose reductase inhibitor Sorbinil

Diabetes ◽

10.2337/diabetes.33.5.470 ◽

1984 ◽

Vol 33 (5) ◽

pp. 470-476 ◽

Cited By ~ 46

Author(s):

D. R. Tomlinson ◽

R. J. Moriarty ◽

J. H. Mayer

Keyword(s):

Axonal Transport ◽

Conduction Velocity ◽

Nerve Conduction ◽

Reductase Inhibitor ◽

Nerve Conduction Velocity ◽

Experimental Diabetes ◽

Motor Nerve ◽

Aldose Reductase Inhibitor ◽

Motor Nerve Conduction Velocity ◽

Motor Nerve Conduction

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Prevention and Reversal of Defective Axonal Transport and Motor Nerve Conduction Velocity In Rats with Experimental Diabetes by Treatment with the Aldose Reductase Inhibitor Sorbinil

Diabetes ◽

10.2337/diab.33.5.470 ◽

1984 ◽

Vol 33 (5) ◽

pp. 470-476 ◽

Cited By ~ 57

Author(s):

D. R. Tomlinson ◽

R. J. Moriarty ◽

J. H. Mayer

Keyword(s):

Axonal Transport ◽

Conduction Velocity ◽

Nerve Conduction ◽

Reductase Inhibitor ◽

Nerve Conduction Velocity ◽

Experimental Diabetes ◽

Motor Nerve ◽

Aldose Reductase Inhibitor ◽

Motor Nerve Conduction Velocity ◽

Motor Nerve Conduction

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Effect of a new aldose reductase inhibitor, 8′-chloro-2′,3′-dihydrospiro [pyrrolidine-3,6′(5′H)-pyrrolo[1,2,3,-de] [1,4]bezoxazine]-2,5,5′-trione (ADN-138), on delayed motor nerve conduction velocity in streptozotocin-diabetic rats

Metabolism ◽

10.1016/s0026-0495(98)90011-7 ◽

1988 ◽

Vol 37 (2) ◽

pp. 159-163 ◽

Cited By ~ 15

Author(s):

Yoshihiro Hirata ◽

Shizuyoshi Fujimori ◽

Kodo Okada

Keyword(s):

Conduction Velocity ◽

Nerve Conduction ◽

Reductase Inhibitor ◽

Nerve Conduction Velocity ◽

Motor Nerve ◽

Diabetic Rats ◽

Aldose Reductase Inhibitor ◽

Motor Nerve Conduction Velocity ◽

Motor Nerve Conduction ◽

Streptozotocin Diabetic Rats

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Ranirestat (AS-3201), a Potent Aldose Reductase Inhibitor, Reduces Sorbitol Levels and Improves Motor Nerve Conduction Velocity in Streptozotocin-Diabetic Rats

Journal of Pharmacological Sciences ◽

10.1254/jphs.08061fp ◽

2008 ◽

Vol 107 (3) ◽

pp. 231-237 ◽

Cited By ~ 28

Author(s):

Takafumi Matsumoto ◽

Yoshiyuki Ono ◽

Masuo Kurono ◽

Akemi Kuromiya ◽

Keiji Nakamura ◽

...

Keyword(s):

Conduction Velocity ◽

Nerve Conduction ◽

Reductase Inhibitor ◽

Nerve Conduction Velocity ◽

Motor Nerve ◽

Diabetic Rats ◽

Aldose Reductase Inhibitor ◽

Motor Nerve Conduction Velocity ◽

Motor Nerve Conduction ◽

Streptozotocin Diabetic Rats

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