Lower rates of endoscopy and higher mortality in end‐stage renal disease patients with gastrointestinal bleeding: A propensity matched national study

2022 ◽  
Author(s):  
Rajat Garg ◽  
Malav P. Parikh ◽  
Pravallika Chadalvada ◽  
Amandeep Singh ◽  
Krishna Sanaka ◽  
...  
Keyword(s):  
Gastrointestinal Bleeding ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
National Study ◽  
Stage Renal Disease ◽  
End Stage

scholarly journals Risk factors for upper gastrointestinal bleeding among end-stage renal disease patients

2003 ◽  
Vol 64 (4) ◽  
pp. 1455-1461 ◽  
Author(s):  
Haimanot Wasse ◽  
Daniel L. Gillen ◽  
Adrianne M. Ball ◽  
Bryan R. Kestenbaum ◽  
Stephen L. Seliger ◽  
...  
Keyword(s):  
Risk Factors ◽  
Gastrointestinal Bleeding ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Upper Gastrointestinal Bleeding ◽  
Stage Renal Disease ◽  
End Stage ◽  
Upper Gastrointestinal

scholarly journals The relation between dialysis-requiring acute kidney injury and recovery from end-stage renal disease: a national study

2019 ◽  
Vol 20 (1) ◽  
Author(s):  
Zijin Chen ◽  
◽  
Benjamin J. Lee ◽  
Charles E. McCulloch ◽  
Nilka Ríos Burrows ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Kidney Injury ◽  
National Study ◽  
Stage Renal Disease ◽  
End Stage

scholarly journals Colonic Mucosal Ulceration and Gastrointestinal Bleeding Associated with Sevelamer Crystal Deposition in a Patient with End Stage Renal Disease

2018 ◽  
Vol 2018 ◽  
pp. 1-3 ◽  
Author(s):  
Sudheer Nambiar ◽  
Unnikrishnan Kunjan Pillai ◽  
Joe Devasahayam ◽  
Tony Oliver ◽  
Asha Karippot
Keyword(s):  
Gastrointestinal Tract ◽  
Gastrointestinal Bleeding ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Crystal Deposition ◽  
Mucosal Ulceration ◽  
Gastrointestinal Bleed ◽  
Stage Renal Disease ◽  
End Stage ◽  
Esrd Patients

End stage renal disease (ESRD) population account for 1.9 per patient year of hospital admissions annually. ESRD population are at increased risk of bleeding secondary to use of anticoagulation during hemodialysis and uremia induced platelet dysfunction. Gastrointestinal bleeding accounts for 3–7% of all deaths in ESRD population. Lower gastrointestinal bleeding refers to blood loss from a site in the gastrointestinal tract distal to the ligament of Treitz. It is usually suspected when a patient complains of hematochezia. It is different from patients presenting with hematemesis that suggests bleeding from upper gastrointestinal tract. Common causes of lower gastrointestinal bleed include diverticulosis, ischemia, hemorrhoids, neoplasia, angiodysplasia, and inflammatory bowel disease. ESRD patients are known to retain phosphate alone or in combination with calcium which has been associated with high mortality. Sevelamer is a phosphate binder used widely in ESRD population. The known side effects of sevelamer include metabolic acidosis, vomiting, nausea, diarrhea, dyspepsia, abdominal pain, constipation, flatulence, fecal impaction, and skin rash. We are reporting a unique case of a 56-year-old female with end stage renal disease on sevelamer hydrochloride who presented with gastrointestinal bleeding and underwent a right hemicolectomy found to have sevelamer-induced mucosal ulceration and crystal deposition in the colonic mucosa. This case report highlights the fact that, with widespread use of this medication in the patients with chronic kidney diseases, physicians should be aware of this underrecognized entity in the differential diagnosis of gastrointestinal bleed in ESRD patients.

scholarly journals Upper gastrointestinal bleeding in patients with end stage renal disease: causes, characteristics and factors associated with need for endoscopic therapeutic intervention

2017 ◽  
Vol 5 (2) ◽  
pp. 106-111 ◽  
Author(s):  
Syed Mudassir Laeeq ◽  
Abbas Ali Tasneem ◽  
Farina M. Hanif ◽  
Nasir Hassan Luck ◽  
Rajesh Mandhwani ◽  
...  
Keyword(s):  
Liver Disease ◽  
Gastrointestinal Bleeding ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Upper Gastrointestinal Bleeding ◽  
Factors Associated ◽  
Stage Renal Disease ◽  
End Stage ◽  
Esrd Patients ◽  
Upper Gastrointestinal

Abstract Background and Objectives The risk of upper gastrointestinal bleeding (UGIB) is increased among the end-stage renal disease (ESRD) patients. The aim of the current study was to describe the causes and characteristics of UGIB in ESRD patients at our center and to assess the need for endoscopic therapeutic intervention (ETI) using Rockall (RS) and Glasgow Blatchford scores (GBS). Material and Methods All patients with ESRD and UGIB with age ≥14 years were included. Frequencies and percentages were computed for categorical variables. Chi square test or Fischer’s exact test was used for statistical analysis. Results A total of 59 subjects had a mean age of 47.25 ± 15 years.The most common endoscopic findings seen were erosions in 33 (55.9%) patients, followed by ulcers in 18 (30.3%) patients. ETI was required in 33 (55.9%) patients, which included adrenaline injection in 19 (32.3%), hemoclip in 9 (15.2%) and argon plasma coagulation in 5 (8.4%) patients. Factors associated with the need of ETI were identified as: a combined presentation of hematemesis and melena (P=0.033), ulcer (P=0.002) and associated chronic liver disease (P=0.015). Six (10.1%) patients died. Death was more common if ETI was not performed (P=0.018). Conclusion ETI was more commonly required in patients on maintenance hemodialysis with UGIB, who had presence of combined hematemesis and melena, ulcers and associated chronic liver disease. A Glasgow Blatchford score of >14 was helpful in assessing the need for ETI in these patients.

scholarly journals 601 Gastrointestinal Bleeding in Patients With Co-Morbid End-Stage Renal Disease

2019 ◽  
Vol 114 (1) ◽  
pp. S350-S350
Author(s):  
Elizabeth Brindise ◽  
Matthew Kobeszko ◽  
Aneesh Kuruvilla ◽  
Imad Elkhatib ◽  
Rogelio Silva
Keyword(s):  
Gastrointestinal Bleeding ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Stage Renal Disease ◽  
End Stage
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