Maternal serum calprotectin level in intrahepatic cholestasis of pregnancy

2021 ◽  
Author(s):  
Recep Taha Agaoglu ◽  
Ozge Yucel Celik ◽  
Kadriye Yakut ◽  
Sevki Celen ◽  
Ali Turhan Caglar
Keyword(s):  
Intrahepatic Cholestasis ◽  
Maternal Serum ◽  
Intrahepatic Cholestasis Of Pregnancy ◽  
Calprotectin Level ◽  
Cholestasis Of Pregnancy

scholarly journals Acidosis: A potential explanation for adverse fetal outcome in intrahepatic cholestasis of pregnancy. A case report

2014 ◽  
Vol 7 (4) ◽  
pp. 177-179 ◽  
Author(s):  
K Sterrenburg ◽  
W Visser ◽  
LS Smit ◽  
J Cornette
Keyword(s):  
Bile Acid ◽  
Intrahepatic Cholestasis ◽  
Fetal Outcome ◽  
Maternal Serum ◽  
Gas Analysis ◽  
Serum Bile Acid ◽  
Intrahepatic Cholestasis Of Pregnancy ◽  
Bile Acid Concentration ◽  
Increased Risk ◽  
Cholestasis Of Pregnancy

Background Intrahepatic cholestasis of pregnancy is a cholestatic disorder with an increased risk for adverse perinatal outcome. The mechanism underlying intrauterine demise is poorly understood. Case A nulliparous woman with gestational age of 36 plus 6 weeks presented with suspected intrahepatic cholestasis. Continuous CTG monitoring evolved from a normal pattern towards a non-reassuring pattern. A male neonate was delivered by caesarean section. Apgar scores 0, 1 and 4 at 1, 5 and 10 min. Fetal cord gas analysis showed pH 6.98, base deficit –15 mmol/L. Blood results showed maternal serum bile acid concentration of 220 µmol/L. Conclusion Our case suggests gradual evolution towards hypoxia and acidosis. It is unknown whether certain components in the bile acid concentrations might contribute to a fetal metabolic component of the acidosis.

Intrahepatic cholestasis of pregnancy levels of sulfated progesterone metabolites downregulate hepatic LXR[a]

2013 ◽  
pp. 1-1
Author(s):  
Vanya Nikolova ◽  
Shadi Abu Hayyeh ◽  
Georgia Papacleovoulou ◽  
Malcolm Parker ◽  
Catherine Williamson
Keyword(s):  
Intrahepatic Cholestasis ◽  
Intrahepatic Cholestasis Of Pregnancy ◽  
Progesterone Metabolites ◽  
Cholestasis Of Pregnancy
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