Impaired Distal Perfusion Predicts Length of Hospital Stay in Patients with Symptomatic Middle Cerebral Artery Stenosis

2021 ◽  
Author(s):  
Shadi Yaghi ◽  
Adam de Havenon ◽  
Tristan Honda ◽  
Jason D. Hinman ◽  
Radoslav Raychev ◽  
...  
Keyword(s):  
Hospital Stay ◽  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Length Of Hospital Stay ◽  
Artery Stenosis ◽  
Distal Perfusion ◽  
Middle Cerebral Artery Stenosis

Hemodynamics is associated with vessel wall remodeling in patients with middle cerebral artery stenosis

2021 ◽  
Author(s):  
Danfeng Zhang ◽  
Xinying Wu ◽  
Jie Tang ◽  
Peng Wang ◽  
Guo Zhong Chen ◽  
...  
Keyword(s):  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Vessel Wall ◽  
Artery Stenosis ◽  
Middle Cerebral Artery Stenosis

scholarly journals A Case of Delayed Symptomatic Middle Cerebral Artery Stenosis Following Mechanical Thrombectomy

2016 ◽  
Vol 10 (3) ◽  
pp. 138-143 ◽  
Author(s):  
Sangnyon Kim ◽  
Masafumi Ohtaki ◽  
Hiroshige Tsuda ◽  
Yusuke Kimura ◽  
Ayaka Sasagawa ◽  
...  
Keyword(s):  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Mechanical Thrombectomy ◽  
Artery Stenosis ◽  
Middle Cerebral Artery Stenosis

scholarly journals Middle Cerebral Artery Stenosis: Endovascular and Surgical Options

Skull Base ◽  
2005 ◽  
Vol 15 (03) ◽  
pp. 175-189 ◽  
Author(s):  
Jeffrey D Klopfenstein ◽  
Francisco A Ponce ◽  
Louis J Kim ◽  
Felipe C Albuquerque ◽  
Peter Nakaji ◽  
...  
Keyword(s):  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Artery Stenosis ◽  
Surgical Options ◽  
Middle Cerebral Artery Stenosis

Atherosclerotic middle cerebral artery stenosis and its risk factors: Clinical and genetic risk factors

2014 ◽  
Vol 235 (2) ◽  
pp. e114-e115 ◽  
Author(s):  
X. Chen ◽  
L. Baum ◽  
H.K. Ng ◽  
K.S. Wong
Keyword(s):  
Risk Factors ◽  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Genetic Risk ◽  
Genetic Risk Factors ◽  
Artery Stenosis ◽  
Middle Cerebral Artery Stenosis

Wall characteristics and mechanisms of ischaemic stroke in patients with atherosclerotic middle cerebral artery stenosis: a high-resolution MRI study

2016 ◽  
Vol 38 (7) ◽  
pp. 606-613 ◽  
Author(s):  
Deng-Ling Zhao ◽  
Gang Deng ◽  
Bo Xie ◽  
Bo Gao ◽  
Cheng-Yu Peng ◽  
...  
Keyword(s):  
High Resolution ◽  
Ischaemic Stroke ◽  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Artery Stenosis ◽  
High Resolution Mri ◽  
Mri Study ◽  
Middle Cerebral Artery Stenosis

Abstract P575: Impaired Distal Perfusion Predicts In-Hospital Outcome in Patients With Symptomatic Middle Cerebral Artery Stenosis

Stroke ◽  
2021 ◽  
Vol 52 (Suppl_1) ◽  
Author(s):  
Shadi Yaghi ◽  
Adam H De Havenon ◽  
Tristan Honda ◽  
Jason D Hinman ◽  
Radoslav I Raychev ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Perfusion Imaging ◽  
Imaging Modality ◽  
Surrogate Marker ◽  
Length Of Hospital Stay ◽  
Continuous Variable ◽  
Mr Perfusion ◽  
Distal Perfusion

Background: Perfusion imaging is increasingly used to risk stratify patients with symptomatic intracranial stenosis. Length of hospital stay (LOS) in patients with ischemic stroke is a surrogate marker of increased morbidity. We aim to determine the association between perfusion delay on T max (< 4 sec, 4-6 sec, and > 6 sec) on perfusion weighted imaging and LOS in patients with symptomatic middle cerebral artery (MCA) stenosis. Methods: We included consecutive patients with left MCA stenosis admitted with ischemic stroke or TIA <7 days from onset who underwent perfusion imaging (CT or MR perfusion) processed with RAPID software. We excluded patients with core infarct ≥ 30 mL. Perfusion mismatch was divided into three groups: mismatch volume ≥ 15 mL based on T max > 6 sec delay, mismatch volume ≥ 15 mL based on T max 4-6 sec delay, and neither of the above mismatch patterns. The primary outcome was LOS, both as a continuous variable and categorical (≥ 7 days (prolonged LOS) vs. <7 days). Results: 179 out of 194 patients met the inclusion criteria; mean age was 70.2 ± 15.4 years, 53.1% were women, median (IQR) NIHSS was 4 (1-9); 83.2% underwent MR perfusion; 38.5% had a mismatch volume ≥ 15 mL based on T max > 6 sec and 31.3% had a mismatch volume ≥ 15 mL based on T max 4-6 sec and the median (IQR) LOS was 4 days (2-8). After adjusting for age and NIHSS, T max > 6 sec mismatch definition was associated with prolonged LOS (OR 2.90 95% CI 1.06-8.18; p=0.039) but T max 4-6 sec definition was not (OR 1.45 95% CI 0.46-4.58, p=0.528), without any interaction based on perfusion imaging modality (p interaction = 0.568). We found similar associations when LOS was considered as a continuous variable for T max > 6 sec (β coefficient=2.01, 95% CI 0.05-3.97, p=0.044) and T max 4-6 sec (β coefficient=1.24, 95% CI -0.85-3.34, p=0.244). In receiver operating curves, the optimal mismatch volume for T max > 6 sec was 10 mL (sensitivity 0.61 and specificity 0.63) whereas for T max 4-6 sec it was 39 mL (sensitivity 0.61 specificity 0.56). Conclusion: In patients with recently symptomatic MCA stenosis, the T max > 6 sec definition for mismatch, but not T max 4-6 sec, is associated with prolonged LOS. Prospective studies are needed to validate our findings and define the optimal mismatch threshold in patients with symptomatic MCA stenosis.

Middle cerebral artery stenosis—a neglected problem?

1988 ◽  
Vol 29 (2) ◽  
pp. 164
Author(s):  
Karl-Fredrik Lindegaard ◽  
Soren Jacob Bakke ◽  
Rune Aaslid ◽  
Helge Nornes
Keyword(s):  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Artery Stenosis ◽  
Middle Cerebral Artery Stenosis

Detection of Microembolic Signals in Patients With Middle Cerebral Artery Stenosis by Means of a Bigate Probe

Stroke ◽  
1996 ◽  
Vol 27 (8) ◽  
pp. 1347-1349 ◽  
Author(s):  
Darius G. Nabavi ◽  
Dimitrios Georgiadis ◽  
Thorsten Mumme ◽  
Peter Zunker ◽  
E. Bernd Ringelstein
Keyword(s):  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Artery Stenosis ◽  
Middle Cerebral Artery Stenosis
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