Co-extrusion as a processing technique to manufacture a dual sustained release fixed-dose combination product

An-Katrien Vynckier; Jody Voorspoels; Jean Paul Remon; Chris Vervaet

doi:10.1111/jphp.12521

Co-extrusion as a processing technique to manufacture a dual sustained release fixed-dose combination product

Journal of Pharmacy and Pharmacology ◽

10.1111/jphp.12521 ◽

2016 ◽

Vol 68 (5) ◽

pp. 721-727 ◽

Cited By ~ 5

Author(s):

An-Katrien Vynckier ◽

Jody Voorspoels ◽

Jean Paul Remon ◽

Chris Vervaet

Keyword(s):

Sustained Release ◽

Processing Technique ◽

Fixed Dose Combination ◽

Fixed Dose ◽

Combination Product ◽

Dose Combination

Pharmacokinetics of atorvastatin and sustained-release metformin fixed-dose combination tablets: two randomized, open-label, 2-way crossover studies in healthy male subjects under fed conditions

Translational and Clinical Pharmacology ◽

10.12793/tcp.2017.25.4.190 ◽

2017 ◽

Vol 25 (4) ◽

pp. 190

Author(s):

Young-Kyung Choi ◽

Sung-Eun Park ◽

Eun-Young Kim ◽

Hyo Ju Park ◽

Eun-Ji Kim ◽

...

Keyword(s):

Sustained Release ◽

Fixed Dose Combination ◽

Fixed Dose ◽

Healthy Male ◽

Open Label ◽

Crossover Studies ◽

Dose Combination ◽

Male Subjects

Pharmacokinetic Equivalence of the High Dose Strength Fixed-Dose Combination Tablet of Gemigliptin/Metformin Sustained Release (SR) and Individual Component Gemigliptin and Metformin XR Tablets in Healthy Subjects

Journal of Korean Medical Science ◽

10.3346/jkms.2018.33.e258 ◽

2018 ◽

Vol 33 (41) ◽

Author(s):

Yong-Soon Cho ◽

Shi Hyang Lee ◽

Hyeong-Seok Lim ◽

Kyun-Seop Bae

Keyword(s):

Sustained Release ◽

Healthy Subjects ◽

Individual Component ◽

Fixed Dose Combination ◽

Fixed Dose ◽

High Dose ◽

Combination Tablet ◽

Dose Combination

Relative bioavailability of isoniazid in a fixed-dose combination product in healthy Mexican subjects

The International Journal of Tuberculosis and Lung Disease ◽

10.5588/ijtld.13.0266 ◽

2014 ◽

Vol 18 (1) ◽

pp. 49-54 ◽

Cited By ~ 3

Author(s):

R. C. Milán-Segovia ◽

M. Vigna-Pérez ◽

M. C. Romero-Méndez ◽

S. E. Medellín-Garibay ◽

J. M. Vargas-Morales ◽

...

Keyword(s):

Relative Bioavailability ◽

Fixed Dose Combination ◽

Fixed Dose ◽

Combination Product ◽

Dose Combination

Bioequivalence Study of a Sustained Release Fixed Dose Combination Capsule Containing Esomeprazole and Domperidone in Healthy Subjects

Arzneimittelforschung ◽

10.1055/s-0031-1296618 ◽

2011 ◽

Vol 57 (05) ◽

pp. 274-277

Author(s):

Sangita Agarwal ◽

KadajjiVeeran Gowda ◽

Uttam Mandal ◽

Debotri Ghosh ◽

Anirbandeep Bose ◽

...

Keyword(s):

Sustained Release ◽

Healthy Subjects ◽

Bioequivalence Study ◽

Fixed Dose Combination ◽

Fixed Dose ◽

Dose Combination

Pharmacokinetics and pharmacodynamics of a fixed-dose combination of gemigliptin/metformin sustained release 25/500 mg compared to the loose combination in healthy male subjects

Translational and Clinical Pharmacology ◽

10.12793/tcp.2020.28.e2 ◽

2020 ◽

Vol 28 (1) ◽

pp. 43

Author(s):

Xuanyou Jin ◽

Eunwoo Kim ◽

Ki Young Huh ◽

Inyoung Hwang ◽

Joo-Youn Cho ◽

...

Keyword(s):

Sustained Release ◽

Fixed Dose Combination ◽

Fixed Dose ◽

Healthy Male ◽

Pharmacokinetics And Pharmacodynamics ◽

Dose Combination ◽

Male Subjects

Bioequivalence of the Highest Dose Strength Fixed-Dose Combination Tablet Of Gemigliptin/Metformin Sustained Release (SR) and Individual Component Gemigliptin and Metformin XR Tablets in Healthy Subjects

Clinical Therapeutics ◽

10.1016/j.clinthera.2017.05.165 ◽

2017 ◽

Vol 39 (8) ◽

pp. e53

Author(s):

Y.-S. Cho ◽

S. Hyang Lee ◽

J. Hyuk Jung ◽

H.-S. Lim ◽

K.-S. Bae

Keyword(s):

Sustained Release ◽

Healthy Subjects ◽

Individual Component ◽

Fixed Dose Combination ◽

Fixed Dose ◽

Combination Tablet ◽

Dose Combination

Comparison of the Pharmacokinetics of a Fixed‐Dose Combination of Rosuvastatin/Metformin Sustained‐Release (10/1000 mg) and Separate Tablets in Healthy Male Subjects

Clinical Pharmacology in Drug Development ◽

10.1002/cpdd.841 ◽

2020 ◽

Author(s):

Ki Young Huh ◽

Eunwoo Kim ◽

Heechan Lee ◽

Inseung Jeon ◽

Hearan Suh ◽

...

Keyword(s):

Sustained Release ◽

Fixed Dose Combination ◽

Fixed Dose ◽

Healthy Male ◽

Dose Combination ◽

Male Subjects ◽

Separate Tablets

Innovative stability-indicating LC-Corona CAD method for simultaneous determination of assay in Artesunate and Mefloquine hydrochloride fixed-dose combination product

Arabian Journal of Chemistry ◽

10.1016/j.arabjc.2021.103657 ◽

2021 ◽

pp. 103657

Author(s):

Wilson Camargo ◽

Diogo Dibo ◽

Monique Silva dos Santos ◽

Ivone de Jesus do Nascimento Lopes ◽

Flávia Furtado de Mendonça de Sousa ◽

...

Keyword(s):

Simultaneous Determination ◽

Fixed Dose Combination ◽

Fixed Dose ◽

Combination Product ◽

Stability Indicating ◽

Dose Combination ◽

Corona Cad

Retrospective survey on efficacy of cefixime-ofloxacin 400 milligram sustained release fixed-dose combination tablet for enteric fever in community settings of India

International Journal of Basic & Clinical Pharmacology ◽

10.18203/2319-2003.ijbcp20151211 ◽

2015 ◽

pp. 1043-1046

Author(s):

Saiprasad Patil ◽

Krishnaprasad Korukonda ◽

Amit Bhargava

Keyword(s):

Sustained Release ◽

Enteric Fever ◽

Fixed Dose Combination ◽

Fixed Dose ◽

Community Settings ◽

Combination Tablet ◽

Retrospective Survey ◽

Dose Combination

Dissolution or disintegration – substitution of dissolution by disintegration testing for a fixed dose combination product

Drug Development and Industrial Pharmacy ◽

10.1080/03639045.2018.1526184 ◽

2018 ◽

Vol 45 (1) ◽

pp. 130-138 ◽

Cited By ~ 2

Author(s):

Achim Grube ◽

Claudia Gerlitzki ◽

Michael Brendel

Keyword(s):

Fixed Dose Combination ◽

Fixed Dose ◽

Combination Product ◽

Dose Combination