Pharmacokinetics of atorvastatin and sustained-release metformin fixed-dose combination tablets: two randomized, open-label, 2-way crossover studies in healthy male subjects under fed conditions

Young-Kyung Choi; Sung-Eun Park; Eun-Young Kim; Hyo Ju Park; Eun-Ji Kim; Geun Seog Song; Jong-Lyul Ghim

doi:10.12793/tcp.2017.25.4.190

Pharmacokinetics of atorvastatin and sustained-release metformin fixed-dose combination tablets: two randomized, open-label, 2-way crossover studies in healthy male subjects under fed conditions

Translational and Clinical Pharmacology ◽

10.12793/tcp.2017.25.4.190 ◽

2017 ◽

Vol 25 (4) ◽

pp. 190

Author(s):

Young-Kyung Choi ◽

Sung-Eun Park ◽

Eun-Young Kim ◽

Hyo Ju Park ◽

Eun-Ji Kim ◽

...

Keyword(s):

Sustained Release ◽

Fixed Dose Combination ◽

Fixed Dose ◽

Healthy Male ◽

Open Label ◽

Crossover Studies ◽

Dose Combination ◽

Male Subjects

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Pharmacokinetics and pharmacodynamics of a fixed-dose combination of gemigliptin/metformin sustained release 25/500 mg compared to the loose combination in healthy male subjects

Translational and Clinical Pharmacology ◽

10.12793/tcp.2020.28.e2 ◽

2020 ◽

Vol 28 (1) ◽

pp. 43

Author(s):

Xuanyou Jin ◽

Eunwoo Kim ◽

Ki Young Huh ◽

Inyoung Hwang ◽

Joo-Youn Cho ◽

...

Keyword(s):

Sustained Release ◽

Fixed Dose Combination ◽

Fixed Dose ◽

Healthy Male ◽

Pharmacokinetics And Pharmacodynamics ◽

Dose Combination ◽

Male Subjects

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Comparison of the Pharmacokinetics of a Fixed‐Dose Combination of Rosuvastatin/Metformin Sustained‐Release (10/1000 mg) and Separate Tablets in Healthy Male Subjects

Clinical Pharmacology in Drug Development ◽

10.1002/cpdd.841 ◽

2020 ◽

Author(s):

Ki Young Huh ◽

Eunwoo Kim ◽

Heechan Lee ◽

Inseung Jeon ◽

Hearan Suh ◽

...

Keyword(s):

Sustained Release ◽

Fixed Dose Combination ◽

Fixed Dose ◽

Healthy Male ◽

Dose Combination ◽

Male Subjects ◽

Separate Tablets

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Pharmacokinetics and bioequivalence of a rosuvastatin/ezetimibe fixed-dose combination tablet versus single agents in healthy male subjects

International Journal of Clinical Pharmacology and Therapeutics ◽

10.5414/cp203026 ◽

2017 ◽

Vol 56 (01) ◽

pp. 43-52 ◽

Cited By ~ 3

Author(s):

Woo Youl Kang ◽

Sook Jin Seong ◽

Boram Ohk ◽

Mi-Ri Gwon ◽

Bo Kyung Kim ◽

...

Keyword(s):

Fixed Dose Combination ◽

Fixed Dose ◽

Healthy Male ◽

Combination Tablet ◽

Dose Combination ◽

Male Subjects

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Pharmacokinetic Comparison of 2 Fixed-Dose Combination Tablets of Amlodipine and Valsartan in Healthy Male Korean Volunteers: A Randomized, Open-Label, 2-Period, Single-Dose, Crossover Study

Clinical Therapeutics ◽

10.1016/j.clinthera.2013.05.021 ◽

2013 ◽

Vol 35 (7) ◽

pp. 934-940 ◽

Cited By ~ 7

Author(s):

Yukyung Kim ◽

Mijeong Son ◽

Donghwan Lee ◽

Hyerang Roh ◽

Hankil Son ◽

...

Keyword(s):

Single Dose ◽

Crossover Study ◽

Fixed Dose Combination ◽

Fixed Dose ◽

Healthy Male ◽

Open Label ◽

Dose Combination

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Pharmacokinetics of a Lobeglitazone/Metformin Fixed-Dose Combination Tablet (CKD-395 0.5/1000 mg) Versus Concomitant Administration of Single Agents and the Effect of Food on the Metabolism of CKD-395 in Healthy Male Subjects

Clinical Pharmacology in Drug Development ◽

10.1002/cpdd.625 ◽

2018 ◽

Vol 8 (5) ◽

pp. 576-584 ◽

Cited By ~ 1

Author(s):

Sun-Young Kim ◽

Ji-Young Jeon ◽

Shin Jung Park ◽

Min-Gul Kim

Keyword(s):

Concomitant Administration ◽

Fixed Dose Combination ◽

Fixed Dose ◽

Healthy Male ◽

Combination Tablet ◽

Effect Of Food ◽

Dose Combination ◽

Male Subjects

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Comparative Pharmacokinetics Between a Fixed‐Dose Combination of Pitavastatin/Valsartan 4/160 mg and the Corresponding Individual Components Through a Partial Replicated Crossover Design in Healthy Male Subjects

Clinical Pharmacology in Drug Development ◽

10.1002/cpdd.1054 ◽

2022 ◽

Author(s):

Joo Young Na ◽

Eunsol Yang ◽

Jae‐Hoon Kim ◽

In Sun Kwon ◽

Eun‐Heui Jin ◽

...

Keyword(s):

Crossover Design ◽

Fixed Dose Combination ◽

Fixed Dose ◽

Healthy Male ◽

Dose Combination ◽

Male Subjects

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Faculty Opinions recommendation of Ledipasvir and sofosbuvir fixed-dose combination with and without ribavirin for 12 weeks in treatment-naive and previously treated Japanese patients with genotype 1 hepatitis C: an open-label, randomised, phase 3 trial.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.725431366.793505980 ◽

2015 ◽

Author(s):

Philip Rosenthal

Keyword(s):

Hepatitis C ◽

Japanese Patients ◽

Fixed Dose Combination ◽

Fixed Dose ◽

Genotype 1 ◽

Open Label ◽

Phase 3 ◽

Treatment Naïve ◽

Dose Combination ◽

Previously Treated

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Bictegravir, Emtricitabine, and Tenofovir Alafenamide Fixed-Dose Combination for Treatment of HIV in Adolescents and Children: Week 48 Results from an Open-Label, Multicentre, Phase 2/3 Paediatric Trial

SSRN Electronic Journal ◽

10.2139/ssrn.3666840 ◽

2020 ◽

Author(s):

Aditya H. Gaur ◽

Mark F. Cotton ◽

Carina A. Rodriguez ◽

Eric J. McGrath ◽

Elizabeth Hellstrom ◽

...

Keyword(s):

Fixed Dose Combination ◽

Fixed Dose ◽

Phase 2 ◽

Open Label ◽

Multicentre Phase ◽

Paediatric Trial ◽

Dose Combination ◽

Tenofovir Alafenamide

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Efficacy of a Fixed-Dose Combination of Ibuprofen and Acetaminophen Compared With Individual Monocomponents in Adult Male Subjects With Endotoxin-Induced Fever: A Randomized Controlled Trial

Clinical Therapeutics ◽

10.1016/j.clinthera.2021.05.004 ◽

2021 ◽

Author(s):

William Smith ◽

Rina Leyva ◽

David Kellstein ◽

Edmund Arthur ◽

Mario Cruz-Rivera

Keyword(s):

Randomized Controlled Trial ◽

Adult Male ◽

Controlled Trial ◽

Fixed Dose Combination ◽

Fixed Dose ◽

Randomized Controlled ◽

Dose Combination ◽

Male Subjects

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Pharmacokinetic Equivalence of the High Dose Strength Fixed-Dose Combination Tablet of Gemigliptin/Metformin Sustained Release (SR) and Individual Component Gemigliptin and Metformin XR Tablets in Healthy Subjects

Journal of Korean Medical Science ◽

10.3346/jkms.2018.33.e258 ◽

2018 ◽

Vol 33 (41) ◽

Author(s):

Yong-Soon Cho ◽

Shi Hyang Lee ◽

Hyeong-Seok Lim ◽

Kyun-Seop Bae

Keyword(s):

Sustained Release ◽

Healthy Subjects ◽

Individual Component ◽

Fixed Dose Combination ◽

Fixed Dose ◽

High Dose ◽

Combination Tablet ◽

Dose Combination

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