High-resolution manometry in patients with eosinophilic esophagitis under topical steroid therapy-a prospective observational study (HIMEOS-study)

2016 ◽  
Vol 28 (4) ◽  
pp. 599-607 ◽  
Author(s):  
S. Nennstiel ◽  
M. Bajbouj ◽  
V. Becker ◽  
J. Slotta-Huspenina ◽  
S. Wagenpfeil ◽  
...  
Keyword(s):  
High Resolution ◽  
Observational Study ◽  
Steroid Therapy ◽  
Eosinophilic Esophagitis ◽  
Prospective Observational Study ◽  
Topical Steroid ◽  
High Resolution Manometry ◽  
Topical Steroid Therapy

scholarly journals Physiological and pathological roles of the accommodation response in lower esophageal sphincter relaxation during wet swallows

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Kazumasa Muta ◽  
Eikichi Ihara ◽  
Shohei Hamada ◽  
Hiroko Ikeda ◽  
Masafumi Wada ◽  
...  
Keyword(s):  
Clinical Practice ◽  
High Resolution ◽  
Observational Study ◽  
Lower Esophageal Sphincter ◽  
Relaxation Function ◽  
Esophagogastric Junction ◽  
Prospective Observational Study ◽  
Outflow Obstruction ◽  
High Resolution Manometry ◽  
Esophageal Sphincter

AbstractThe preparatory accommodation response of lower esophageal sphincter (LES) before swallowing is one of the mechanisms involved in LES relaxation during wet swallows, however, the physiological and/or pathological roles of LES accommodation remain to be determined in humans. To address this problem, we conducted a prospective observational study of 38 patients with normal high-resolution manometry (HRM) and 23 patients with idiopathic esophagogastric junction outflow obstruction (EGJOO) to assess dry and wet swallows. The LES accommodation measurement was proposed for practical use in evaluating the LES accommodation response. Although swallow-induced LES relaxation was observed in both dry and wet swallows, LES accommodation (6.4, 3.1–11.1 mmHg) was only observed in wet swallows. The extent of LES accommodation was impaired in idiopathic EGJOO (0.6, − 0.6–6 mmHg), and the LES accommodation measurement of patients with idiopathic EGJOO (36.8, 29.5–44.3 mmHg) was significantly higher in comparison to those with normal HRM (23.8, 18–28.6 mmHg). Successful LES relaxation in wet swallowing can be achieved by LES accommodation in combination with swallow-induced LES relaxation. Impaired LES accommodation is characteristic of idiopathic EGJOO. In addition to the IRP value, the LES accommodation measurement may be useful for evaluating the LES relaxation function in clinical practice.

Update on topical steroid therapy for eosinophilic esophagitis

2015 ◽  
Vol 38 (6) ◽  
pp. 388-397 ◽  
Author(s):  
Javier Molina-Infante ◽  
Alfredo J. Lucendo
Keyword(s):  
Steroid Therapy ◽  
Eosinophilic Esophagitis ◽  
Topical Steroid ◽  
Topical Steroid Therapy

Mo1175 Diminishing Effectiveness of Maintenance Topical Steroid Therapy on Long-term Endoscopic and Histologic Outcomes in Eosinophilic Esophagitis

2016 ◽  
Vol 150 (4) ◽  
pp. S658-S659 ◽  
Author(s):  
Swathi Eluri ◽  
Thomas Runge ◽  
Jason Hansen ◽  
Bharati Kochar ◽  
Craig C. Reed ◽  
...  
Keyword(s):  
Steroid Therapy ◽  
Eosinophilic Esophagitis ◽  
Topical Steroid ◽  
Topical Steroid Therapy

scholarly journals Maintenance Topical Steroid Therapy in Eosinophilic Esophagitis: Not So Hard to Swallow Any More?

2020 ◽  
Vol 159 (5) ◽  
pp. 1653-1655
Author(s):  
Ikuo Hirano ◽  
Stuart Jon Spechler
Keyword(s):  
Steroid Therapy ◽  
Eosinophilic Esophagitis ◽  
Topical Steroid ◽  
Topical Steroid Therapy

Montelukast Does not Maintain Symptom Remission After Topical Steroid Therapy for Eosinophilic Esophagitis

2017 ◽  
Vol 15 (2) ◽  
pp. 214-221.e2 ◽  
Author(s):  
Jeffrey A. Alexander ◽  
Karthik Ravi ◽  
Felicity T. Enders ◽  
Debra M. Geno ◽  
Lori A. Kryzer ◽  
...  
Keyword(s):  
Steroid Therapy ◽  
Eosinophilic Esophagitis ◽  
Topical Steroid ◽  
Topical Steroid Therapy ◽  
Symptom Remission

scholarly journals Diminishing Effectiveness of Long-Term Maintenance Topical Steroid Therapy in PPI Non-Responsive Eosinophilic Esophagitis

2017 ◽  
Vol 8 (6) ◽  
pp. e97 ◽  
Author(s):  
Swathi Eluri ◽  
Thomas M Runge ◽  
Jason Hansen ◽  
Bharati Kochar ◽  
Craig C Reed ◽  
...  
Keyword(s):  
Steroid Therapy ◽  
Eosinophilic Esophagitis ◽  
Topical Steroid ◽  
Topical Steroid Therapy ◽  
Term Maintenance

Su1834 Topical Steroid Therapy Efficiently Reduces the Risk for Long Lasting Food Impactions Requiring Endoscopic Removal in Eosinophilic Esophagitis

2013 ◽  
Vol 144 (5) ◽  
pp. S-486
Author(s):  
Alain Schoepfer ◽  
Tanja Kuchen ◽  
Ekaterina Safroneeva ◽  
Susanne Portmann ◽  
Christian Bussmann ◽  
...  
Keyword(s):  
Steroid Therapy ◽  
Eosinophilic Esophagitis ◽  
Topical Steroid ◽  
Endoscopic Removal ◽  
Topical Steroid Therapy

scholarly journals Topical Steroid Therapy for the Treatment of Eosinophilic Esophagitis (EoE): A Systematic Review and Meta-Analysis

2015 ◽  
Vol 6 (3) ◽  
pp. e82 ◽  
Author(s):  
Ming-yu (Anthony) Chuang ◽  
Mohamed A Chinnaratha ◽  
David G Hancock ◽  
Richard Woodman ◽  
Geoffrey R Wong ◽  
...  
Keyword(s):  
Systematic Review ◽  
Steroid Therapy ◽  
Eosinophilic Esophagitis ◽  
Meta Analysis ◽  
Topical Steroid ◽  
Topical Steroid Therapy

A case of cytomegalovirus esophagitis during topical steroid therapy for eosinophilic esophagitis

2020 ◽  
Vol 13 (6) ◽  
pp. 1046-1050 ◽  
Author(s):  
Ken Suzaki ◽  
Katsumasa Kobayashi ◽  
Mana Matsuoka ◽  
Yukito Okura ◽  
Takahito Nozaka ◽  
...  
Keyword(s):  
Steroid Therapy ◽  
Eosinophilic Esophagitis ◽  
Topical Steroid ◽  
Topical Steroid Therapy
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