Reducing ICD Test Shocks with a Simplified Upper Limit of Vulnerability

2016 ◽  
Vol 39 (7) ◽  
pp. 652-657 ◽  
Author(s):  
MICHAEL PITTARO ◽  
WILLIAM DEFORGE ◽  
MARK W. KROLL
Keyword(s):  
Upper Limit ◽  
Upper Limit Of Vulnerability

scholarly journals How Hyperpolarization and the Recovery of Excitability Affect Propagation through a Virtual Anode in the Heart

2011 ◽  
Vol 2011 ◽  
pp. 1-8 ◽  
Author(s):  
Nicholas P. Charteris ◽  
Bradley J. Roth
Keyword(s):  
Wave Front ◽  
Time Constant ◽  
Computer Model ◽  
Propagation Speed ◽  
One Dimensional ◽  
Upper Limit ◽  
Rapid Propagation ◽  
Upper Limit Of Vulnerability ◽  
Key Factor ◽  
Sodium Inactivation

Researchers have suggested that the fate of a shock-induced wave front at the edge of a “virtual anode” (a region hyperpolarized by the shock) is a key factor determining success or failure during defibrillation of the heart. In this paper, we use a simple one-dimensional computer model to examine propagation speed through a hyperpolarized region. Our goal is to test the hypothesis that rapid propagation through a virtual anode can cause failure of propagation at the edge of the virtual anode. The calculations support this hypothesis and suggest that the time constant of the sodium inactivation gate is an important parameter. These results may be significant in understanding the mechanism of the upper limit of vulnerability.

Effects of n-3 polyunsaturated fatty acid on upper limit of vulnerability shocks

2006 ◽  
Vol 107 (3) ◽  
pp. 299-302 ◽  
Author(s):  
Nipon Chattipakorn ◽  
Krekwit Shinlapawittayatorn ◽  
Rattapong Sungnoon ◽  
Siriporn C. Chattipakorn
Keyword(s):  
Fatty Acid ◽  
Polyunsaturated Fatty Acid ◽  
Upper Limit ◽  
Upper Limit Of Vulnerability
Sign in / Sign up

Export Citation Format

Share Document