Assessment of Adequate Safety Margin Using Single Coupling Interval-Upper Limit of Vulnerability Test

2013 ◽  
Vol 37 (1) ◽  
pp. 95-103 ◽  
Author(s):  
MEHUL B. PATEL ◽  
KHYATI PANDYA ◽  
RANJAN K. THAKUR
Keyword(s):  
Safety Margin ◽  
Upper Limit ◽  
Upper Limit Of Vulnerability ◽  
Coupling Interval ◽  
Single Coupling

Safe Use of the Assimilative Capacity of the Marine Environment for Waste Disposal – Is It Feasible?

1986 ◽  
Vol 18 (4-5) ◽  
pp. 233-244 ◽  
Author(s):  
J. E. Portmann ◽  
R. Lloyd
Keyword(s):  
Marine Environment ◽  
Salt Marshes ◽  
Safety Margin ◽  
Assimilative Capacity ◽  
Anthropogenic Inputs ◽  
Upper Limit ◽  
Safe Limits ◽  
Control Authority ◽  
The Right ◽  
To Receive

For centuries the sea has absorbed a variety of inputs from rivers, streams, salt marshes and the atmosphere. It is generally accepted that additional limited inputs by man are unlikely to have a significant effect on the marine environment. Various control systems have been constructed to provide a framework within which the regulation of anthropogenic inputs can be achieved. These are briefly reviewed. With care, and in the light of past experience in both freshwater and marine environments, reasonable assumptions or estimations can be applied where uncertainties exist; safe limits can therefore be set for discharges. Case histories are used to illustrate the contention that it is possible to assess the assimilative capacity of a marine area to receive wastes. There is a major distinction to be drawn between contamination and pollution of the marine environment. Moreover, acknowledgement of the assimilative capacity concept in the marine environment does not automatically provide dischargers with the right to utilise that capacity either in part or to the upper limit. What it does is indicate the upper limit which must not be exceeded if pollution is to be avoided, and provide an indication to the control authority of the safety margin involved in the discharge limits they set accordingly.

scholarly journals Enhanced Transmural Fiber Rotation and Connexin 43 Heterogeneity Are Associated With an Increased Upper Limit of Vulnerability in a Transgenic Rabbit Model of Human Hypertrophic Cardiomyopathy

2007 ◽  
Vol 101 (10) ◽  
pp. 1049-1057 ◽  
Author(s):  
Crystal M. Ripplinger ◽  
Wenwen Li ◽  
Jennifer Hadley ◽  
Junjie Chen ◽  
Florence Rothenberg ◽  
...  
Keyword(s):  
Hypertrophic Cardiomyopathy ◽  
Connexin 43 ◽  
Rabbit Model ◽  
Transgenic Rabbit ◽  
Upper Limit ◽  
Upper Limit Of Vulnerability

scholarly journals Patient-tailored implantable cardioverter defibrillator testing using the upper limit of vulnerability: the TULIP protocol

EP Europace ◽  
2008 ◽  
Vol 10 (8) ◽  
pp. 907-913 ◽  
Author(s):  
B. Lemke ◽  
T. Lawo ◽  
M. Zarse ◽  
A. Lubinski ◽  
U. Kreutzer ◽  
...  
Keyword(s):  
Implantable Cardioverter Defibrillator ◽  
Cardioverter Defibrillator ◽  
Upper Limit ◽  
Upper Limit Of Vulnerability

Critical Points and the Upper Limit of Vulnerability for Defibrillation

2008 ◽  
pp. 165-187
Author(s):  
Raymond E. Ideker ◽  
Derek J. Dosdall
Keyword(s):  
Critical Points ◽  
Upper Limit ◽  
Upper Limit Of Vulnerability

The Upper Limit of Vulnerability and Critical Points for Defibrillation

2021 ◽  
pp. 107-119
Author(s):  
Derek J. Dosdall ◽  
Raymond E. Ideker
Keyword(s):  
Critical Points ◽  
Upper Limit ◽  
Upper Limit Of Vulnerability

scholarly journals How Hyperpolarization and the Recovery of Excitability Affect Propagation through a Virtual Anode in the Heart

2011 ◽  
Vol 2011 ◽  
pp. 1-8 ◽  
Author(s):  
Nicholas P. Charteris ◽  
Bradley J. Roth
Keyword(s):  
Wave Front ◽  
Time Constant ◽  
Computer Model ◽  
Propagation Speed ◽  
One Dimensional ◽  
Upper Limit ◽  
Rapid Propagation ◽  
Upper Limit Of Vulnerability ◽  
Key Factor ◽  
Sodium Inactivation

Researchers have suggested that the fate of a shock-induced wave front at the edge of a “virtual anode” (a region hyperpolarized by the shock) is a key factor determining success or failure during defibrillation of the heart. In this paper, we use a simple one-dimensional computer model to examine propagation speed through a hyperpolarized region. Our goal is to test the hypothesis that rapid propagation through a virtual anode can cause failure of propagation at the edge of the virtual anode. The calculations support this hypothesis and suggest that the time constant of the sodium inactivation gate is an important parameter. These results may be significant in understanding the mechanism of the upper limit of vulnerability.

Effects of n-3 polyunsaturated fatty acid on upper limit of vulnerability shocks

2006 ◽  
Vol 107 (3) ◽  
pp. 299-302 ◽  
Author(s):  
Nipon Chattipakorn ◽  
Krekwit Shinlapawittayatorn ◽  
Rattapong Sungnoon ◽  
Siriporn C. Chattipakorn
Keyword(s):  
Fatty Acid ◽  
Polyunsaturated Fatty Acid ◽  
Upper Limit ◽  
Upper Limit Of Vulnerability
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