scholarly journals Proteoglycan synthesis in Conserved Oligomeric Golgi ( COG ) subunit deficient HEK293T cells is affected differently, depending on the lacking subunit

Traffic ◽  
2021 ◽  
Author(s):  
Ravi Adusumalli ◽  
Hans‐Christian Åsheim ◽  
Vladimir Lupashin ◽  
Jessica B Blackburn ◽  
Kristian Prydz
Keyword(s):  
Proteoglycan Synthesis ◽  
Conserved Oligomeric Golgi

The Effect of Total Meniscectomy versus Caudal Pole Hemimeniscectomy on the Stifle Joint of the Sheep

1999 ◽  
Vol 12 (02) ◽  
pp. 56-63 ◽  
Author(s):  
C. R. Bellenger ◽  
P. Ghosh ◽  
Y. Numata ◽  
C. Little ◽  
D. S. Simpson
Keyword(s):  
Tissue Culture ◽  
Articular Cartilage ◽  
Fibrous Tissue ◽  
Cartilage Degeneration ◽  
Medial Compartment ◽  
Proteoglycan Synthesis ◽  
Stifle Joint ◽  
Medial Meniscectomy ◽  
Tibial Condyle ◽  
Articular Cartilage Degeneration

SummaryTotal medial meniscectomy and caudal pole hemimeniscectomy were performed on the stifle joints of twelve sheep. The two forms of meniscectomy produced a comparable degree of postoperative lameness that resolved within two weeks of the operations. After six months the sheep were euthanatised and the stifle joints examined. Fibrous tissue that replaced the excised meniscus in the total meniscectomy group did not cover as much of the medial tibial condyle as the residual cranial pole and caudal fibrous tissue observed following hemimeniscectomy. The articular cartilage from different regions within the joints was examined for gross and histological evidence of degeneration. Analyses of the articular cartilage for water content, glycosaminoglycan composition and DNA content were performed. The proteoglycan synthesis and release from explanted articular cartilage samples in tissue culture were also measured. There were significant pathological changes in the medial compartment of all meniscectomised joints. The degree of articular cartilage degeneration that was observed following total meniscectomy and caudal pole meniscectomy was similar. Caudal pole hemimeniscectomy, involving transection of the meniscus, causes the same degree of degeneration of the stifle joint that occurs following total meniscectomy.The effect of total medial meniscectomy versus caudal pole hemimeniscectomy on the stifle joint of sheep was studied experimentally. Six months after the operations gross pathology, histopathology, cartilage biochemical analysis and the rate of proteoglycan synthesis in tissue culture were used to compare the articular cartilage harvested from the meniscectomised joints. Degeneration of the articular cartilage from the medial compartment of the joints was present in both of the groups. Caudal pole hemimeniscectomy induces a comparable degree of articular cartilage degeneration to total medial meniscectomy in the sheep stifle joint.

Galactosyltransferase-1 deficiency: a novel cause of bone fragility due to impaired proteoglycan synthesis

2015 ◽  
Author(s):  
Rebecca Moon ◽  
Claire Salter ◽  
Nicola Foulds ◽  
Justin Davies
Keyword(s):  
Bone Fragility ◽  
Proteoglycan Synthesis

Proteoglycan Synthesis in Porcine Nasal Cartilage Grafts Following Nd:YAG (λ = 1.32 μm) Laser-Mediated Reshaping

2000 ◽  
Vol 71 (2) ◽  
pp. 218 ◽  
Author(s):  
Brian J. F. Wong ◽  
Thomas E. Milner ◽  
Hong K. Kim ◽  
Ken Chao ◽  
Chung-Ho Sun ◽  
...  
Keyword(s):  
Proteoglycan Synthesis ◽  
Nasal Cartilage ◽  
Cartilage Grafts

scholarly journals Demonstration of receptors for insulin and insulin-like growth factors on Swarm rat chondrosarcoma chondrocytes. Evidence that insulin stimulates proteoglycan synthesis through the insulin receptor.

1982 ◽  
Vol 257 (2) ◽  
pp. 663-669
Author(s):  
T.P. Foley ◽  
S.P. Nissley ◽  
R.L. Stevens ◽  
G.L. King ◽  
V.C. Hascall ◽  
...  
Keyword(s):  
Growth Factors ◽  
Insulin Receptor ◽  
Proteoglycan Synthesis ◽  
Insulin Like Growth Factors

Proteoglycan synthesis and deposition in fetal rat bone

Biochemistry ◽  
1984 ◽  
Vol 23 (7) ◽  
pp. 1572-1576 ◽  
Author(s):  
Graeme K. Hunter ◽  
Johan N. M. Heersche ◽  
Jane E. Aubin
Keyword(s):  
Proteoglycan Synthesis ◽  
Fetal Rat ◽  
Rat Bone

Mutations in proteins of the Conserved Oligomeric Golgi Complex affect polarity, cell wall structure, and glycosylation in the filamentous fungus Aspergillus nidulans

2014 ◽  
Vol 73 ◽  
pp. 69-82 ◽  
Author(s):  
S.K. Gremillion ◽  
S.D. Harris ◽  
L. Jackson-Hayes ◽  
S.G.W. Kaminskyj ◽  
D.M. Loprete ◽  
...  
Keyword(s):  
Cell Wall ◽  
Aspergillus Nidulans ◽  
Golgi Complex ◽  
Filamentous Fungus ◽  
Cell Wall Structure ◽  
Wall Structure ◽  
Conserved Oligomeric Golgi Complex ◽  
Conserved Oligomeric Golgi

Effects of anti-arthritic drugs on proteoglycan synthesis by equine cartilage

2002 ◽  
Vol 25 (4) ◽  
pp. 289-298 ◽  
Author(s):  
S. P. Frean ◽  
H. Cambridge ◽  
P. Lees
Keyword(s):  
Proteoglycan Synthesis
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