scholarly journals Solvent-dependent rate-limiting steps in the conformational change of sodium channel gating in squid giant axon

1997 ◽  
Vol 499 (3) ◽  
pp. 849-849
Keyword(s):  
Sodium Channel ◽  
Conformational Change ◽  
Channel Gating ◽  
Giant Axon ◽  
Squid Giant Axon ◽  
Dependent Rate ◽  
Rate Limiting

scholarly journals Inhibitory effects of myrmicacin on the sodium channel in the squid giant axon.

1981 ◽  
Vol 57 (8) ◽  
pp. 314-317 ◽  
Author(s):  
Toshifumi TAKENAKA ◽  
Hidenori HORIE ◽  
Hideaki HORI ◽  
Tohru YOSHIOKA ◽  
Yozo IWANAMI
Keyword(s):  
Sodium Channel ◽  
Giant Axon ◽  
Squid Giant Axon ◽  
Inhibitory Effects

scholarly journals Analysis of sodium current fluctuations in the cut-open squid giant axon.

1984 ◽  
Vol 83 (2) ◽  
pp. 133-142 ◽  
Author(s):  
I Llano ◽  
F Bezanilla
Keyword(s):  
Sodium Channel ◽  
Sodium Channels ◽  
Sodium Current ◽  
Giant Axon ◽  
Squid Giant Axon ◽  
Statistical Techniques ◽  
Current Fluctuations ◽  
Small Populations ◽  
Squid Axon ◽  
Single Sodium Channel

Patch pipettes were used to record the current arising from small populations of sodium channels in voltage-clamped cut-open squid axons. The current fluctuations associated with the time-variant sodium conductance were analyzed with nonstationary statistical techniques in order to obtain an estimate for the conductance of a single sodium channel. The results presented support the notion that the open sodium channel in the squid axon has only one value of conductance, 3.5 pS.

Conduction velocity and gating current in the squid giant axon

1975 ◽  
Vol 189 (1094) ◽  
pp. 81-86 ◽  
Keyword(s):  
Sodium Channel ◽  
Conduction Velocity ◽  
Charged Particles ◽  
Giant Axon ◽  
Squid Giant Axon ◽  
Gating Current ◽  
Giant Axons ◽  
Sodium Conductance ◽  
Conduction Velocities

As predicted by Hodgkin (1975), calculation of conduction velocities in squid giant axons shows that if each sodium channel is gated by charged particles moving in the membrane field there will be a maximum in the relation between sodium conductance and conduction velocity.

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