This issue of International Journal of Vehicle Structures and Systems covers a special issue covering the best papers selected on peer review basis and edited by the Guest Editors as above. These 7 papers are from the research papers presented in the special session on Vehicle Structure and System Design at the 2nd International Conference on Future Learning Aspects of Mechanical Engineering (FLAME - 2020) organised by the Department of Mechanical Engineering, Amity School of Engineering and Technology, Amity University, Noida, Uttar Pradesh, India from 5th August to 7th August 2020. A short biography of each Guest Editor is also provided as further information for this special issue.