A Simulator for the In Vitro Study of the Dynamics of the Aortic Valve: Design and Test

2009 ◽  
Author(s):  
Riccardo Vismara ◽  
Dario Comparolo ◽  
Andrea Mangini ◽  
Carlo Antona ◽  
Gianfranco B. Fiore
Keyword(s):  
Animal Models ◽  
Aortic Valve ◽  
Heart Valves ◽  
In Vitro Study ◽  
Vitro Study ◽  
Valve Design ◽  
Experimental Conditions ◽  
Insight Into ◽  
Physiological Complexity

The in vitro approach to the study of the hemodynamics of heart valves allows easier-to-control and well repeatable experimental conditions, if compared with studies on animal models. A deep, detailed insight into specific issues is possible, despite the unavoidable simplification of the physiological complexity.

Bicuspid Aortic Valves Are Associated With Increased Turbulence Compared to Pure Aortic Stenosis: An In Vitro Study

2012 ◽  
Author(s):  
Neelakantan Saikrishnan ◽  
Nicole C. Milligan ◽  
Ajit P. Yoganathan
Keyword(s):  
Aortic Valve ◽  
Aortic Stenosis ◽  
Genetic Defect ◽  
In Vitro Study ◽  
Coarctation Of The Aorta ◽  
Vitro Study ◽  
Cardiac Anomaly ◽  
Aortic Dilatation ◽  
Congenital Cardiac Anomaly

In about 1–2% of all live births, the human aortic valve only consists of two anomalous leaflets and is known as the bicuspid aortic valve (BAV). BAVs are the most common congenital cardiac anomaly, and are associated with significant valvular dysfunction, including calcific aortic stenosis (AS) and aortic regurgitation (AR), as well as aortic wall abnormalities including coarctation of the aorta, ascending aortic dilatation and aneurysms [1]. Many studies have proposed a common underlying genetic defect in progression of complications with BAVs [2]. However, other recent studies have also suggested that the altered hemodynamic environment associated with BAVs could also be responsible for accelerated disease progression in these patients [3, 4]. A recent in vitro study showed elevated levels of turbulence associated with BAVs, and indicated that fluid flow patterns in the aortic sinuses are also affected due to the altered valve morphology [5]. The present work seeks to compare the levels of turbulence in BAVs to pure trileaflet aortic stenosis models.

scholarly journals IN VITRO STUDY OF BONE MARROW

Blood ◽  
1947 ◽  
Vol 2 (Special_Issue_Number_1) ◽  
pp. 33-41 ◽  
Author(s):  
CLAUS MUNK PLUM
Keyword(s):  
Bone Marrow ◽  
In Vitro Study ◽  
Vitro Study ◽  
Insight Into

Abstract Two types of apparatus are described for the culture of bone marrow in vitro. The first, a macro method, is suited to the study of large amounts of bone marrow. The second, a micro method, allows observations of the development of individual cells. Studies of erythropoiesis by these technics has allowed insight into production of erythrocytes. These data will be reported in a subsequent article.

scholarly journals CRT-800.12 Effect Of Transcatheter Aortic Valve Size And Position On Valve-in-valve Hemodynamics: An In-vitro Study

2017 ◽  
Vol 10 (3) ◽  
pp. S66
Author(s):  
Matheus Simonato ◽  
Ali Azadani ◽  
Michael Reardon ◽  
Gabriel Aldea ◽  
Georg Nickenig ◽  
...  
Keyword(s):  
Aortic Valve ◽  
In Vitro Study ◽  
Vitro Study ◽  
Transcatheter Aortic Valve ◽  
Valve Size ◽  
Valve In Valve

In vitro study of blood flow in aortic valve and Valsalva sinus

2004 ◽  
Vol 2004.5 (0) ◽  
pp. 185-186
Author(s):  
Shinnichi IIDA ◽  
Kenkichi OHBA ◽  
Tsutomu TAJIKAWA ◽  
Masataka YOSHIDA ◽  
Fuyo TSUKIYAMA
Keyword(s):  
Blood Flow ◽  
Aortic Valve ◽  
In Vitro Study ◽  
Vitro Study
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