Use of genetic algorithms for computer-aided diagnosis of breast cancers from image features

Author(s):  
Carey E. Floyd, Jr. ◽  
Georgia D. Tourassi ◽  
Jay A. Baker
2014 ◽  
Vol 2014 ◽  
pp. 1-12 ◽  
Author(s):  
D. K. Iakovidis ◽  
T. Goudas ◽  
C. Smailis ◽  
I. Maglogiannis

Image segmentation and annotation are key components of image-based medical computer-aided diagnosis (CAD) systems. In this paper we present Ratsnake, a publicly available generic image annotation tool providing annotation efficiency, semantic awareness, versatility, and extensibility, features that can be exploited to transform it into an effective CAD system. In order to demonstrate this unique capability, we present its novel application for the evaluation and quantification of salient objects and structures of interest in kidney biopsy images. Accurate annotation identifying and quantifying such structures in microscopy images can provide an estimation of pathogenesis in obstructive nephropathy, which is a rather common disease with severe implication in children and infants. However a tool for detecting and quantifying the disease is not yet available. A machine learning-based approach, which utilizes prior domain knowledge and textural image features, is considered for the generation of an image force field customizing the presented tool for automatic evaluation of kidney biopsy images. The experimental evaluation of the proposed application of Ratsnake demonstrates its efficiency and effectiveness and promises its wide applicability across a variety of medical imaging domains.


Author(s):  
Aswini Kumar Mohanty ◽  
Saroj Kumar Lenka

Diagnostic decision-making in pulmonary medical imaging has been improved by computer-aided diagnosis (CAD) systems, serving as second readers to detect suspicious nodules for diagnosis by a radiologist. Though increasing the accuracy, these CAD systems rarely offer useful descriptions of the suspected nodule or their decision criteria, mainly due to lack of nodule data. In this paper, we present a framework for mapping image features to radiologist-defined diagnostic criteria based on the newly available data). Using data mining, we found promising mappings to clinically relevant, human-interpretable nodule characteristics such as malignancy, margin, spiculation, subtlety, and texture. Bridging the semantic gap between computed image features and radiologist defined diagnostic criteria allows CAD systems to offer not only a second opinion but also decision-support criteria usable by radiologists. Presenting transparent decisions will improve the clinical acceptance of CAD.


Author(s):  
Issam El Naqa ◽  
Jung Hun Oh ◽  
Yongyi Yang

With the ever-growing volume of images used in medicine, the capability to retrieve relevant images from large databases is becoming increasingly important. Despite the recent progress made in the field, its applications in Computer-Aided Diagnosis (CAD) thus far have been limited by the ability to determine the intrinsic mapping between high-level user perception and the underlying low-level image features. Relevance Feedback (RFB) is a post-query process to refine the search by using positive and/or negative indications from the user about the relevance of retrieved images, which has been applied successfully in traditional text-retrieval systems for improving the results of a retrieval strategy. In this chapter, the authors review some recent advances in RFB technology, and discuss its expanding role in content-based image retrieval from medical archives. They provide working examples, based on their experience, for developing machine-learning methods for RFB in mammography and highlight the potential opportunities in this field for CAD applications and clinical decision-making.


2002 ◽  
Vol 15 (1-2) ◽  
pp. 45-52 ◽  
Author(s):  
Elisabet Golobardes ◽  
Xavier Llorà ◽  
Maria Salamó ◽  
Joan Martı́

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