SU-F-BRD-12: When Does Pencil Beam Scanning Become Superior to Passive Scattered Proton Therapy for Pediatric Head and Neck Cancers?

2015 ◽  
Vol 42 (6Part25) ◽  
pp. 3528-3528 ◽  
Author(s):  
M Moteabbed ◽  
N Depauw ◽  
H Kooy ◽  
T Yock ◽  
H Paganetti
Keyword(s):  
Head And Neck ◽  
Proton Therapy ◽  
Head And Neck Cancers ◽  
Pencil Beam ◽  
Beam Scanning ◽  
Pencil Beam Scanning ◽  
Scattered Proton

Pencil Beam Scanning Intensity Modulated Proton Therapy for Head and Neck Cancers Involving Skull Base

2016 ◽  
Vol 77 (S 01) ◽  
Author(s):  
Robert Malyapa ◽  
Damien Weber ◽  
Ralf Schneider ◽  
Lorentzos Mikroutsikos ◽  
Alessandra Bolsi ◽  
...  
Keyword(s):  
Head And Neck ◽  
Skull Base ◽  
Proton Therapy ◽  
Head And Neck Cancers ◽  
Pencil Beam ◽  
Beam Scanning ◽  
Intensity Modulated Proton Therapy ◽  
Intensity Modulated ◽  
Pencil Beam Scanning

scholarly journals Clinical outcomes of head and neck adenoid cystic carcinoma patients treated with pencil beam-scanning proton therapy

Oral Oncology ◽  
2020 ◽  
Vol 107 ◽  
pp. 104752
Author(s):  
Maciej J. Pelak ◽  
Marc Walser ◽  
Barbara Bachtiary ◽  
Jan Hrbacek ◽  
Anthony J. Lomax ◽  
...  
Keyword(s):  
Adenoid Cystic Carcinoma ◽  
Head And Neck ◽  
Clinical Outcomes ◽  
Proton Therapy ◽  
Pencil Beam ◽  
Beam Scanning ◽  
Pencil Beam Scanning ◽  
Adenoid Cystic

scholarly journals PO-162 Patient outcome of pencil beam-scanning proton therapy in Head and Neck adenoid cystic carcinoma

2019 ◽  
Vol 132 ◽  
pp. 86
Author(s):  
M. Pelak ◽  
M. Walser ◽  
B. Bachtiary ◽  
A. Bolsi ◽  
J. Hrbacek ◽  
...  
Keyword(s):  
Patient Outcome ◽  
Adenoid Cystic Carcinoma ◽  
Head And Neck ◽  
Proton Therapy ◽  
Pencil Beam ◽  
Beam Scanning ◽  
Pencil Beam Scanning ◽  
Adenoid Cystic

Evaluation of Robustness to Setup and Range Uncertainties for Head and Neck Patients Treated With Pencil Beam Scanning Proton Therapy

2016 ◽  
Vol 95 (1) ◽  
pp. 154-162 ◽  
Author(s):  
Robert Malyapa ◽  
Matthew Lowe ◽  
Alessandra Bolsi ◽  
Antony J. Lomax ◽  
Damien C. Weber ◽  
...  
Keyword(s):  
Head And Neck ◽  
Proton Therapy ◽  
Pencil Beam ◽  
Beam Scanning ◽  
Pencil Beam Scanning

scholarly journals Pencil beam scanning versus passively scattered proton therapy for unresectable pancreatic cancer

2018 ◽  
Vol 9 (4) ◽  
pp. 687-693 ◽  
Author(s):  
Michael Chuong ◽  
Shahed N. Badiyan ◽  
Man Yam ◽  
Zuofeng Li ◽  
Katja Langen ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Proton Therapy ◽  
Pencil Beam ◽  
Unresectable Pancreatic Cancer ◽  
Beam Scanning ◽  
Pencil Beam Scanning ◽  
Scattered Proton

scholarly journals Radiation-induced optic neuropathy after pencil beam scanning proton therapy for skull-base and head and neck tumours

2020 ◽  
Vol 93 (1107) ◽  
pp. 20190028 ◽  
Author(s):  
Melpomeni Kountouri ◽  
Alessia Pica ◽  
Marc Walser ◽  
Francesca Albertini ◽  
Alessandra Bolsi ◽  
...  
Keyword(s):  
Head And Neck ◽  
Skull Base ◽  
Optic Neuropathy ◽  
Proton Therapy ◽  
High Dose ◽  
Pencil Beam ◽  
Beam Scanning ◽  
Optic Chiasma ◽  
Pencil Beam Scanning ◽  
Radiation Induced

Objective: To assess the radiation-induced optic neuropathy (RION) prevalence, following high dose pencil beam scanning proton therapy (PBSPT) to skull base and head and neck (H&N) tumours Methods: Between 1999 and 2014, 216 adult patients, median age 47 years (range, 18–77), were treated with PBS PT for skull base or H&N malignancies, delivering ≥45 GyRBE to the optic nerve(s) (ON) and/or optic chiasma (OC). The median administered dose to the planning target volume was 74.0 GyRBE (range, 54.0–77.4). The median follow-up was 5.3 years (range, 0.8–15.9). Results: RION was observed in 14 (6.5%) patients at a median time of 13.2 months (range, 4.8–42.6) following PBSPT. Most (92.9%) of RION were symptomatic. Most affected patients (11/14; 79%) developed unilateral toxicity. Grade 4, 3, 2 and 1 toxicity was observed in 10, 2, 1 and 1 patients, respectively. On univariate analyses, age (<70 vs ≥70 years; p < 0.0001), hypertension (p = 0.0007) and tumour abutting the optic apparatus (p = 0.012) were associated with RION. OC’s V60 GyRBE was of border line significance (p = 0.06). None of the other evaluated OC–ON dose/volume metrics (Dmax, Dmean, V40-60) were significantly associated with this complication. Conclusion: These data suggest that high-dose PBS PT for skull base and H&N tumours is associated with a low prevalence of RION. Caution should be however exercised when treating elderly/hypertensive patients with tumours abutting the optic apparatus. Advances in knowledge: This is the first study reporting the risk of developing RION following proton therapy with PBS technique, demonstrating the safety of this treatment.

TU-A-108-10: Pencil Beam Scanning Vs. Passive Scattered Proton Therapy for Pediatric Thoracic/pelvic Cancers

2013 ◽  
Vol 40 (6Part25) ◽  
pp. 421-421 ◽  
Author(s):  
M Moteabbed ◽  
T Yock ◽  
H Paganetti
Keyword(s):  
Proton Therapy ◽  
Pencil Beam ◽  
Beam Scanning ◽  
Pencil Beam Scanning ◽  
Scattered Proton
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