Limited Brain Distribution of [3R,4R,5S]-4-Acetamido-5-amino-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylate Phosphate (Ro 64-0802), a Pharmacologically Active Form of Oseltamivir, by Active Efflux across the Blood-Brain Barrier Mediated by Organic Anion Transporter 3 (Oat3/Slc22a8) and Multidrug Resistance-Associated Protein 4 (Mrp4/Abcc4)

2008 ◽  
Vol 37 (2) ◽  
pp. 315-321 ◽  
Author(s):  
Atsushi Ose ◽  
Mototsugu Ito ◽  
Hiroyuki Kusuhara ◽  
Kenzo Yamatsugu ◽  
Motomu Kanai ◽  
...  
Keyword(s):  
Multidrug Resistance ◽  
Blood Brain Barrier ◽  
Organic Anion ◽  
Active Form ◽  
Organic Anion Transporter ◽  
Brain Distribution ◽  
Active Efflux ◽  
Anion Transporter ◽  
Pharmacologically Active ◽  
Organic Anion Transporter 3
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