Protein Binding and Hepatic Clearance: Re-Examining the Discrimination between Models of Hepatic Clearance with Diazepam in the Isolated Perfused Rat Liver Preparation

Perfused Rat Liver ◽

Protein binding and hepatic clearance: Discrimination between models of hepatic clearance with diazepam, a drug of high intrinsic clearance, in the isolated perfused rat liver preparation

Journal of Pharmacokinetics and Biopharmaceutics ◽

10.1007/bf01059274 ◽

1984 ◽

Vol 12 (2) ◽

pp. 129-147 ◽

Cited By ~ 42

Author(s):

Malcolm Rowland ◽

David Leitch ◽

George Fleming ◽

Barbara Smith

Keyword(s):

Protein Binding ◽

Rat Liver ◽

Hepatic Clearance ◽

Intrinsic Clearance ◽

Perfused Rat Liver ◽

Protein binding and hepatic clearance: Studies with tolbutamide, a drug of low intrinsic clearance, in the isolated perfused rat liver preparation

Journal of Pharmacokinetics and Biopharmaceutics ◽

10.1007/bf01061866 ◽

1983 ◽

Vol 11 (3) ◽

pp. 225-243 ◽

Cited By ~ 37

Author(s):

William L. Schary ◽

Malcolm Rowland

Keyword(s):

Protein Binding ◽

Rat Liver ◽

Hepatic Clearance ◽

Intrinsic Clearance ◽

Perfused Rat Liver ◽

Clearance Studies ◽

Hepatic clearance of norepinephrine (NE) in the isolated perfused rat liver

Journal of Hepatology ◽

10.1016/s0168-8278(85)80411-6 ◽

1985 ◽

Vol 1 ◽

pp. S188

Keyword(s):

Rat Liver ◽

Hepatic Clearance ◽

Perfused Rat Liver

Uptake and rate of metabolism of vinyl chloride by the isolated perfused rat liver preparation

International Archives of Occupational and Environmental Health ◽

10.1007/bf00575154 ◽

1977 ◽

Vol 40 (2) ◽

pp. 101-110 ◽

Cited By ~ 4

Author(s):

Z. Radwan ◽

D. Henschler

Keyword(s):

Vinyl Chloride ◽

Rat Liver ◽

Perfused Rat Liver ◽

Chemical reactivity, metabolic oxirane formation and biological reactivity of chlorinated ethylenes in the isolated perfused rat liver preparation

Biochemical Pharmacology ◽

10.1016/0006-2952(75)90468-2 ◽

1975 ◽

Vol 24 (19) ◽

pp. 1829-1834 ◽

Cited By ~ 111

Author(s):

G. Bonse ◽

Th. Urban ◽

D. Reichert ◽

D. Henschler

Keyword(s):

Rat Liver ◽

Chemical Reactivity ◽

Perfused Rat Liver ◽

Chlorinated Ethylenes ◽

Hepatic clearance and retention of aluminium: studies in the isolated perfused rat liver

Toxicology Letters ◽

10.1016/s0378-4274(96)03824-6 ◽

1996 ◽

Vol 89 (3) ◽

pp. 257-263 ◽

Cited By ~ 19

Author(s):

Michael Whihelm ◽

Daphne E. Jaeger ◽

Heike Schüll-Cablitz ◽

Dieter Hafner ◽

Helga Idel

Keyword(s):

Rat Liver ◽

Hepatic Clearance ◽

Perfused Rat Liver

The isolated perfused rat liver: Preparation and application

Analytical Biochemistry ◽

10.1016/0003-2697(87)90127-8 ◽

1987 ◽

Vol 167 (1) ◽

pp. 1-14 ◽

Cited By ~ 40

Author(s):

Allan W. Wolkoff ◽

Kirsten L. Johansen ◽

Tobias Goeser

Keyword(s):

Rat Liver ◽

Perfused Rat Liver ◽

Metabolism of Halothane as a Function of Substrate Concentration in the Isolated Perfused Rat Liver Preparation

Deutsche Pharmakologische Gesellschaft ◽

10.1007/978-3-662-39532-5_86 ◽

1978 ◽

pp. 22-22

Author(s):

I. Rösch ◽

E. Dallmeier

Keyword(s):

Rat Liver ◽

Substrate Concentration ◽

Perfused Rat Liver ◽

LIVER INJURY IN ISOLATED PERFUSED RAT LIVER PREPARATION EXPOSED TO CHLOROFORM

Survey of Anesthesiology ◽

10.1097/00132586-196204010-00014 ◽

1962 ◽

Vol 6 (2) ◽

pp. 120???121

Author(s):

R. W. BRAUER ◽

G. F. LEONG ◽

R. J. HOLLOWAY

Keyword(s):

Liver Injury ◽

Rat Liver ◽

Perfused Rat Liver ◽

Physiologic Models of Hepatic Drug Clearance: Influence of Altered Protein Binding on the Elimination of Diclofenac in the Isolated Perfused Rat Liver

Journal of Pharmaceutical Sciences ◽

10.1002/jps.2600820904 ◽

1993 ◽

Vol 82 (9) ◽

pp. 880-885 ◽

Cited By ~ 13

Author(s):

Ziad Hussein ◽

Allan M. Evans ◽

Malcolm Rowland

Keyword(s):

Protein Binding ◽

Rat Liver ◽

Drug Clearance ◽

Perfused Rat Liver ◽

Hepatic Drug ◽

Altered Protein ◽

Physiologic Models