Phosphonate O-Deethylation of [4-(4-Bromo-2-Cyano-Phenylcarbamoyl) Benzyl]-Phosphonic Acid Diethyl Ester, a Lipoprotein Lipase-Promoting Agent, Catalyzed by Cytochrome P450 2C8 and 3A4 in Human Liver Microsomes

2002 ◽  
Vol 30 (3) ◽  
pp. 301-306 ◽  
Author(s):  
Yujiro Morioka ◽  
Makiko Otsu ◽  
Shinsaku Naito ◽  
Teruko Imai
Keyword(s):  
Cytochrome P450 ◽  
Lipoprotein Lipase ◽  
Phosphonic Acid ◽  
Human Liver ◽  
Liver Microsomes ◽  
Human Liver Microsomes ◽  
Diethyl Ester ◽  
Cytochrome P450 2C8

CYTOCHROME P450 2C8 (CYP2C8)-MEDIATED HYDROXYLATION OF AN ENDOTHELIN ETA RECEPTOR ANTAGONIST IN HUMAN LIVER MICROSOMES

2004 ◽  
Vol 32 (5) ◽  
pp. 473-478 ◽  
Author(s):  
Bennett Ma ◽  
Raju Subramanian ◽  
Michael L. Schrag ◽  
A. David Rodrigues ◽  
Cuyue Tang
Keyword(s):  
Cytochrome P450 ◽  
Receptor Antagonist ◽  
Human Liver ◽  
Liver Microsomes ◽  
Human Liver Microsomes ◽  
Cytochrome P450 2C8 ◽  
Eta Receptor ◽  
Eta Receptor Antagonist

Cytochrome P450 2C8 and CYP3A4/5 are involved in chloroquine metabolism in human liver microsomes

2003 ◽  
Vol 26 (8) ◽  
pp. 631-637 ◽  
Author(s):  
Kyoung-Ah Kim ◽  
Ji-Young Park ◽  
Ji-Suk Lee ◽  
Sabina Lim
Keyword(s):  
Cytochrome P450 ◽  
Human Liver ◽  
Liver Microsomes ◽  
Human Liver Microsomes ◽  
Cytochrome P450 2C8

Deactivation of anti-cancer drug letrozole to a carbinol metabolite by polymorphic cytochrome P450 2A6 in human liver microsomes

Xenobiotica ◽  
2009 ◽  
Vol 00 (00) ◽  
pp. 090901052053001-8
Author(s):  
K. Murai ◽  
H. Yamazaki ◽  
K. Nakagawa ◽  
R. Kawai ◽  
T. Kamataki
Keyword(s):  
Cytochrome P450 ◽  
Human Liver ◽  
Liver Microsomes ◽  
Human Liver Microsomes ◽  
Cancer Drug ◽  
Anti Cancer ◽  
Cytochrome P450 2A6

Selegiline Metabolism and Cytochrome P450 Enzymes:In vitro Study in Human Liver Microsomes*

2000 ◽  
Vol 86 (5) ◽  
pp. 215-221 ◽  
Author(s):  
Paivi Taavitsainen ◽  
Markku Anttila ◽  
Leena Nyman ◽  
Hari Karnani ◽  
Jarmo S. Salonen ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Human Liver ◽  
Liver Microsomes ◽  
Human Liver Microsomes ◽  
Vitro Study

scholarly journals Roles of cytochrome P450 2A6 in the oxidation of flavone, 4´-hydroxyflavone, and 4´-, 3´-, and 2´-methoxyflavones by human liver microsomes

Xenobiotica ◽  
2021 ◽  
pp. 1-47
Author(s):  
Haruna Nagayoshi ◽  
Norie Murayama ◽  
Shigeo Takenaka ◽  
Vitchan Kim ◽  
Donghak Kim ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Human Liver ◽  
Liver Microsomes ◽  
Human Liver Microsomes ◽  
Cytochrome P450 2A6

Effect of Commonly Used Organic Solvents on the Kinetics of Cytochrome P450 2B6- and 2C8-Dependent Activity in Human Liver Microsomes

2007 ◽  
Vol 35 (11) ◽  
pp. 1990-1995 ◽  
Author(s):  
Ragini Vuppugalla ◽  
Shu-Ying Chang ◽  
Hongjian Zhang ◽  
Punit H. Marathe ◽  
David A. Rodrigues
Keyword(s):  
Cytochrome P450 ◽  
Organic Solvents ◽  
Human Liver ◽  
Liver Microsomes ◽  
Human Liver Microsomes ◽  
Cytochrome P450 2B6 ◽  
Dependent Activity ◽  
Kinetics Of

Inhibition of Cytochrome P450 by Nomilin and Obacunone and Potential Mechanism in Human Liver Microsomes

2017 ◽  
Vol 9 (3) ◽  
pp. 295-298 ◽  
Author(s):  
Yao-wen Fan ◽  
Yun-long Chen ◽  
Jun-xiu Chen ◽  
Fang-liang Zhang ◽  
Gregory Ondieki ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Human Liver ◽  
Liver Microsomes ◽  
Human Liver Microsomes ◽  
Potential Mechanism
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