Static and Dynamic Projections of Drug-Drug Interactions Caused by Cytochrome P450 3A Time-Dependent Inhibitors Measured in Human Liver Microsomes and Hepatocytes

2021 ◽  
pp. DMD-AR-2021-000497
Author(s):  
Elaine Tseng ◽  
Heather Eng ◽  
Jian Lin ◽  
Matthew A. Cerny ◽  
David A. Tess ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Drug Interactions ◽  
Human Liver ◽  
Liver Microsomes ◽  
Human Liver Microsomes ◽  
Time Dependent ◽  
Cytochrome P450 3A

Metabolism of FK506, a potent immunosuppressive agent, by cytochrome P450 3A enzymes in rat, dog and human liver microsomes

1994 ◽  
Vol 47 (4) ◽  
pp. 727-735 ◽  
Author(s):  
Toshipumi Shiraga ◽  
Hiroji Matsuda ◽  
Kazuko Nagase ◽  
Kazuhide Iwasaki ◽  
Kosei Noda ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Human Liver ◽  
Liver Microsomes ◽  
Immunosuppressive Agent ◽  
Human Liver Microsomes ◽  
Cytochrome P450 3A

Involvement of cytochrome P450 3A enzyme family in the major metabolic pathways of toremifene in human liver microsomes

1994 ◽  
Vol 47 (10) ◽  
pp. 1883-1895 ◽  
Author(s):  
François Berthou ◽  
Yvonne Dreano ◽  
Claire Belloc ◽  
Lauri Kangas ◽  
Jean-Charles Gautier ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Metabolic Pathways ◽  
Human Liver ◽  
Liver Microsomes ◽  
Human Liver Microsomes ◽  
Cytochrome P450 3A ◽  
Enzyme Family

Amiodarone N-deethylation in human liver microsomes : Involvement of cytochrome P450 3A enzymes (first report)

Life Sciences ◽  
1993 ◽  
Vol 52 (10) ◽  
pp. PL91-PL96 ◽  
Author(s):  
Jean-Marc Trivier ◽  
Christian Libersa ◽  
Claire Belloc ◽  
Michel Lhermitte
Keyword(s):  
Cytochrome P450 ◽  
Human Liver ◽  
Liver Microsomes ◽  
Human Liver Microsomes ◽  
Cytochrome P450 3A ◽  
First Report

scholarly journals Potential of Lansoprazole as a Novel Probe for Cytochrome P450 3A Activity by Measuring Lansoprazole Sulfone in Human Liver Microsomes

2009 ◽  
Vol 32 (8) ◽  
pp. 1422-1426 ◽  
Author(s):  
Yohei Yanagida ◽  
Minoru Watanabe ◽  
Yuko Takeba ◽  
Toshio Kumai ◽  
Naoki Matsumoto ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Human Liver ◽  
Liver Microsomes ◽  
Human Liver Microsomes ◽  
Cytochrome P450 3A

CYTOCHROME P450 3A-MEDIATED METABOLISM OF BUSPIRONE IN HUMAN LIVER MICROSOMES

2005 ◽  
Vol 33 (4) ◽  
pp. 500-507 ◽  
Author(s):  
Mingshe Zhu ◽  
Weiping Zhao ◽  
Humberto Jimenez ◽  
Donglu Zhang ◽  
Suresh Yeola ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Human Liver ◽  
Liver Microsomes ◽  
Human Liver Microsomes ◽  
Cytochrome P450 3A
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