Regulation of Rat Hepatic Cytochrome P450 Expression by Sterol Biosynthesis Inhibition: Inhibitors of Squalene Synthase Are Potent Inducers of CYP2B Expression in Primary Cultured Rat Hepatocytes and Rat Liver

P450 Expression ◽

Cultured Rat Hepatocytes ◽

Hepatic Cytochrome

Hepatic Cytochrome P450s Attenuate the Cytotoxicity Induced by Leflunomide and Its Active Metabolite A77 1726 in Primary Cultured Rat Hepatocytes

Toxicological Sciences ◽

10.1093/toxsci/kfr106 ◽

2011 ◽

Vol 122 (2) ◽

pp. 579-586 ◽

Cited By ~ 22

Author(s):

Qiang Shi ◽

Xi Yang ◽

James Greenhaw ◽

William F. Salminen

Keyword(s):

Active Metabolite ◽

Rat Hepatocytes ◽

Cytochrome P450s ◽

Cultured Rat Hepatocytes ◽

Hepatic Cytochrome

Non-coplanar 2,2′,3,3′,4,4′,5,5′,6,6′-decachlorobiphenyl (PCB 209) did not induce cytochrome P450 enzyme activities in primary cultured rat hepatocytes, was not genotoxic, and did not exhibit endocrine-modulating activities

Toxicology ◽

10.1016/j.tox.2008.10.013 ◽

2009 ◽

Vol 255 (3) ◽

pp. 177-186 ◽

Cited By ~ 4

Author(s):

Xing Han ◽

John C. O’Connor ◽

E. Maria Donner ◽

Diane L. Nabb ◽

Robert T. Mingoia ◽

...

Keyword(s):

Cytochrome P450 ◽

Enzyme Activities ◽

Rat Hepatocytes ◽

Cytochrome P450 Enzyme ◽

P450 Enzyme ◽

Pharmacodynamics of cytochrome P450 2B induction by phenobarbital, 5-ethyl-5-phenylhydantoin, and 5-ethyl-5-phenyloxazolidinedione in the male rat liver or in cultured rat hepatocytes

Chemical Research in Toxicology ◽

10.1021/tx00032a008 ◽

1993 ◽

Vol 6 (2) ◽

pp. 188-196 ◽

Cited By ~ 8

Author(s):

Raymond W. Nims ◽

Peter R. Sinclair ◽

Jacqueline F. Sinclair ◽

Paul E. Thomas ◽

Collins R. Jones ◽

...

Keyword(s):

Cytochrome P450 ◽

Rat Liver ◽

Rat Hepatocytes ◽

Male Rat ◽

Cultured Rat Hepatocytes ◽

Induction By Phenobarbital

Increased adenylate energy charges in rat liver or primary cultured rat hepatocytes by diisopropyl 1,3-dithiol-2-ylidenemalonate

General Pharmacology The Vascular System ◽

10.1016/0306-3623(87)90161-3 ◽

1987 ◽

Vol 18 (1) ◽

pp. 13-15

Author(s):

Mitsuo Itakura ◽

Masami Tsuchiya ◽

Kamejiro Yamashita ◽

Toshitsugu Oda

Keyword(s):

Rat Liver ◽

Rat Hepatocytes ◽

Detection by 32P-postlabelling of 8-oxo-7,8-dihydro-2′-deoxyguanosine in DNA as biomarker of microcystin-LR- and nodularin-induced DNA damage in vitro in primary cultured rat hepatocytes and in vivo in rat liver

Mutation Research/Genetic Toxicology and Environmental Mutagenesis ◽

10.1016/j.mrgentox.2004.06.010 ◽

2004 ◽

Vol 564 (1) ◽

pp. 9-20 ◽

Cited By ~ 46

Author(s):

Imed Maatouk ◽

Noureddine Bouaïcha ◽

Marie José Plessis ◽

François Périn

Keyword(s):

Dna Damage ◽

Rat Liver ◽

Rat Hepatocytes ◽

Genotoxic potential of Microcystin-LR and nodularinin vitro in primary cultured rat hepatocytes andin vivo in rat liver

Environmental Toxicology ◽

10.1002/tox.20110 ◽

2005 ◽

Vol 20 (3) ◽

pp. 341-347 ◽

Cited By ~ 39

Author(s):

Noureddine Bouaïcha ◽

Imed Maatouk ◽

Marie-José Plessis ◽

François Périn

Keyword(s):

Rat Liver ◽

Rat Hepatocytes ◽

Genotoxic Potential ◽

Imipramine- and mianserin-induced acute cell injury in primary cultured rat hepatocytes: implication of different cytochrome P450 enzymes

Archives of Toxicology ◽

10.1007/s002040050599 ◽

1999 ◽

Vol 73 (3) ◽

pp. 147-151 ◽

Cited By ~ 7

Author(s):

Yasuhiro Masubuchi ◽

Maki Konishi ◽

Toshiharu Horie

Keyword(s):

Cytochrome P450 ◽

Cell Injury ◽

Rat Hepatocytes ◽

Cytochrome P450 Enzymes ◽

Effect of benomyl on cytochrome P450 in primary cultured rat hepatocytes

Toxicology Letters ◽

10.1016/0378-4274(95)94901-r ◽

1995 ◽

Vol 78 ◽

pp. 68

Author(s):

S. Radice ◽

B. Cipelletti ◽

E. Chiesara ◽

L. Marabini

Keyword(s):

Cytochrome P450 ◽

Rat Hepatocytes ◽

Hepatoprotective Activity of Water Extracts from Chaga Medicinal Mushroom, Inonotus obliquus (Higher Basidiomycetes) Against Tert-Butyl Hydroperoxide-Induced Oxidative Liver Injury in Primary Cultured Rat Hepatocytes

International Journal of Medicinal Mushrooms ◽

10.1615/intjmedmushrooms.v17.i11.70 ◽

2015 ◽

Vol 17 (11) ◽

pp. 1069-1076 ◽

Cited By ~ 3

Author(s):

Ki Bae Hong ◽

Dong Ouk Noh ◽

Yooheon Park ◽

Hyung Joo Suh

Keyword(s):

Liver Injury ◽

Rat Hepatocytes ◽

Hepatoprotective Activity ◽

Medicinal Mushroom ◽

Inonotus Obliquus ◽

Butyl Hydroperoxide ◽

Water Extracts ◽

Tert Butyl Hydroperoxide ◽

Platelet-activating factor stimulates metabolism of phosphoinositides via phospholipase A2 in primary cultured rat hepatocytes.

The Journal of Lipid Research ◽

10.1016/s0022-2275(20)38644-2 ◽

1987 ◽

Vol 28 (7) ◽

pp. 760-767

Author(s):

T Okayasu ◽

K Hasegawa ◽

T Ishibashi

Keyword(s):

Phospholipase A2 ◽

Platelet Activating Factor ◽

Rat Hepatocytes ◽