scholarly journals In Vitro Activity of OPT-80 against Clostridium difficile

2004 ◽  
Vol 48 (6) ◽  
pp. 2280-2282 ◽  
Author(s):  
Grit Ackermann ◽  
Birgit Löffler ◽  
Daniela Adler ◽  
Arne C. Rodloff
Keyword(s):  
Clostridium Difficile ◽  
Anaerobic Bacteria ◽  
Vitro Activity ◽  
In Vitro Activity ◽  
Obligately Anaerobic ◽  
Nosocomial Diarrhea ◽  
Frequent Relapses

ABSTRACT Clostridium difficile remains the major cause of nosocomial diarrhea. Reports on impaired susceptibility of C. difficile to metronidazole and vancomycin and frequent relapses of patients after therapy necessitate the search for new substances. With this study, the activity of OPT-80, a new macrocycle, against 207 C. difficile strains and against other obligately anaerobic bacteria was tested. OPT-80 showed high in vitro activity against all C. difficile strains tested.

scholarly journals Comparative In Vitro Activities of Gemifloxacin, Other Quinolones, and Nonquinolone Antimicrobials against Obligately Anaerobic Bacteria

2001 ◽  
Vol 45 (6) ◽  
pp. 1896-1899 ◽  
Author(s):  
Niels Kleinkauf ◽  
Grit Ackermann ◽  
Reiner Schaumann ◽  
Arne C. Rodloff
Keyword(s):  
Anaerobic Bacteria ◽  
Vitro Activity ◽  
In Vitro Activity ◽  
Dilution Technique ◽  
Gram Negative ◽  
Obligately Anaerobic ◽  
Agar Dilution

ABSTRACT The in vitro activity of gemifloxacin was compared to that of other quinolone and nonquinolone antimicrobials against 204 anaerobes by the agar dilution technique. The data indicate that gemifloxacin has a rather selective anaerobic activity. Most Peptostreptococcus, Porphyromonas, and Fusobacterium species are susceptible, while gemifloxacin's activity against other gram-negative anaerobes appears to be variable.

In Vitro Activity of New Quinolones against Anaerobic Bacteria

Drugs ◽  
1995 ◽  
Vol 49 (Supplement 2) ◽  
pp. 233-234
Author(s):  
Carl Erik Nord ◽  
Ann Lindmark ◽  
Ingela Persson
Keyword(s):  
Anaerobic Bacteria ◽  
Vitro Activity ◽  
In Vitro Activity ◽  
New Quinolones

scholarly journals The in-vitro activity of trovafloxacin and nine other antimicrobials against 413 anaerobic bacteria

1996 ◽  
Vol 38 (2) ◽  
pp. 271-281 ◽  
Author(s):  
K. E. Bowker ◽  
M. Wootton ◽  
H. A. Holt ◽  
D. S. Reeves ◽  
A. P. MacGowan
Keyword(s):  
Anaerobic Bacteria ◽  
Vitro Activity ◽  
In Vitro Activity

scholarly journals Bay 12-8039, a new 8-methoxy-quinolone: comparative in-vitro activity with nine other antimicrobials against anaerobic bacteria

1997 ◽  
Vol 40 (4) ◽  
pp. 503-509 ◽  
Author(s):  
A. P. MacGowan ◽  
K. E. Bowker ◽  
H. A. Holt ◽  
M. Wootton ◽  
D. S. Reeves
Keyword(s):  
Anaerobic Bacteria ◽  
Vitro Activity ◽  
In Vitro Activity

In vitro activity of cadazolid against Clostridium difficile strains isolated from primary and recurrent infections in Stockholm, Sweden

Anaerobe ◽  
2013 ◽  
Vol 20 ◽  
pp. 32-35 ◽  
Author(s):  
Mamun-Ur Rashid ◽  
Helena Martinez Lozano ◽  
Andrej Weintraub ◽  
Carl Erik Nord
Keyword(s):  
Clostridium Difficile ◽  
Vitro Activity ◽  
Recurrent Infections ◽  
In Vitro Activity

scholarly journals In vitro activity of cefbuperazone, a new cephamycin, against anaerobic bacteria.

1985 ◽  
Vol 27 (4) ◽  
pp. 640-642 ◽  
Author(s):  
R H Prabhala ◽  
H Thadepalli ◽  
B Rao ◽  
M B Bansal ◽  
R Marshall
Keyword(s):  
Anaerobic Bacteria ◽  
Vitro Activity ◽  
In Vitro Activity
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