Streptococcus pyogenes Infection in Mouse Skin Leads to a Time-Dependent Up-Regulation of Protein H Expression
2003 ◽
Vol 71
(10)
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pp. 6079-6082
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Keyword(s):
ABSTRACT Streptococcus pyogenes protein H (sph) is an immunoglobulin-binding protein present in the Mga regulon of certain M1 serotype isolates. Although sph is present in many strains, it is frequently not expressed. In this paper we show that protein H was highly expressed after bacteria were injected into the skin of mice and were recovered from the blood, kidney, or spleen at various times postinfection. The percentage of protein H-positive colonies increased with time, reaching 100% in the spleen and kidney within 24 to 72 h postinfection. The up-regulation of sph expression was also observed in a mga mutant.
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2001 ◽
Vol 73
(3)
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pp. 942-948
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Keyword(s):
1995 ◽
Vol 32
(16)
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pp. 1235-1243
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2009 ◽
Vol 75
(4)
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pp. 931-953
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Keyword(s):
2008 ◽
Vol 45
(1)
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pp. 94-101
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1995 ◽
Vol 80
(1)
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pp. 1-5
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