scholarly journals Two tonB Systems Function in Iron Transport in Vibrio anguillarum, but Only One Is Essential for Virulence

2004 ◽  
Vol 72 (12) ◽  
pp. 7326-7329 ◽  
Author(s):  
Michiel Stork ◽  
Manuela Di Lorenzo ◽  
Susana Mouriño ◽  
Carlos R. Osorio ◽  
Manuel L. Lemos ◽  
...  
Keyword(s):  
Marine Fish ◽  
Iron Transport ◽  
Vibrio Anguillarum ◽  
Iron Limitation ◽  
Fish Pathogen

ABSTRACT We have identified two functional tonB systems in the marine fish pathogen Vibrio anguillarum, tonB1 and tonB2. Each of the tonB genes is transcribed in an operon with the cognate exbB and exbD genes in response to iron limitation. Only tonB2 is essential for transport of ferric anguibactin and virulence.

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