scholarly journals False-Positive Transcription-Mediated Amplification Assay Detection of West Nile Virus in Blood from a Patient with Viremia Caused by an Usutu Virus Infection

2010 ◽  
Vol 48 (9) ◽  
pp. 3338-3339 ◽  
Author(s):  
P. Gaibani ◽  
A. M. Pierro ◽  
F. Cavrini ◽  
G. Rossini ◽  
M. P. Landini ◽  
...  
Keyword(s):  
West Nile Virus ◽  
Virus Infection ◽  
False Positive ◽  
West Nile ◽  
Usutu Virus ◽  
Amplification Assay ◽  
Assay Detection

scholarly journals West Nile virus infection in individuals with pre-existing Usutu virus immunity, northern Italy, 2018

2019 ◽  
Vol 24 (21) ◽  
Author(s):  
Alessandro Sinigaglia ◽  
Monia Pacenti ◽  
Thomas Martello ◽  
Silvana Pagni ◽  
Elisa Franchin ◽  
...  
Keyword(s):  
West Nile Virus ◽  
Virus Infection ◽  
West Nile Virus Infection ◽  
Northern Italy ◽  
Cross Protection ◽  
West Nile ◽  
Usutu Virus ◽  
Virus Immunity

In 2018, there was a large West Nile virus (WNV) outbreak in northern Italy. We observed five atypical cases of WNV infection that were characterised by the presence of WNV RNA and WNV IgG at the time of diagnosis, but no IgM response during follow-up. Neutralisation assays demonstrated pre-existing Usutu virus immunity in all patients. Besides challenging diagnosis, the immunological crosstalk between the two viruses warrants further investigation on possible cross-protection or infection enhancement effects.

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