scholarly journals Comparison of a new, rapid enzyme-linked immunosorbent assay with latex particle agglutination for the detection of Haemophilus influenzae type b infections.

1985 ◽  
Vol 21 (5) ◽  
pp. 711-714 ◽  
Author(s):  
A B Macone ◽  
G Arakere ◽  
J M Letourneau ◽  
D A Goldmann
PEDIATRICS ◽  
1982 ◽  
Vol 69 (4) ◽  
pp. 466-471
Author(s):  
Robert S. Daum ◽  
George R. Siber ◽  
Jill S. Kamon ◽  
Rebecca R. Russell

The effectiveness of a commercially available latex particle agglutination test (Bactogen) in the diagnosis of invasive Haemophilus influenzae type b infection was evaluated. Bactogen correctly diagnosed all 27 patients with bacteriologically proven H influenzae type b infection (sensitivity 100%). Two of 39 patients with proven, non-H influenzae type b infections had false-postive tests (specificity 95%). One of 103 sera and 0 of 55 urine specimens from hospitalized adults contained detectable H influenzae type b antigen. Bactogen is a sensitive, specific, commercially available test for rapid diagnosis of H influenzae type b infection.


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