Structure of Respiratory Syncytial Virus Fusion Glycoprotein in the Postfusion Conformation Reveals Preservation of Neutralizing Epitopes

Journal of Virology ◽

10.1128/jvi.00555-11 ◽

2011 ◽

Vol 85 (15) ◽

pp. 7788-7796 ◽

Author(s):

J. S. McLellan ◽

Y. Yang ◽

B. S. Graham ◽

P. D. Kwong

Keyword(s):

Respiratory Syncytial Virus ◽

Virus Fusion ◽

Fusion Glycoprotein ◽

Syncytial Virus ◽

Neutralizing Epitopes

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Neutralizing epitopes on the respiratory syncytial virus fusion glycoprotein

Current Opinion in Virology ◽

10.1016/j.coviro.2015.03.002 ◽

2015 ◽

Vol 11 ◽

pp. 70-75 ◽

Author(s):

Jason S McLellan

Keyword(s):

Respiratory Syncytial Virus ◽

Virus Fusion ◽

Fusion Glycoprotein ◽

Syncytial Virus ◽

Neutralizing Epitopes

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Conformational constraints of conserved neutralizing epitopes from a major antigenic area of human respiratory syncytial virus fusion glycoprotein

Journal of General Virology ◽

10.1099/0022-1317-74-12-2567 ◽

1993 ◽

Vol 74 (12) ◽

pp. 2567-2577 ◽

Author(s):

J. A. Lopez ◽

D. Andreu ◽

C. Carreno ◽

P. Whyte ◽

G. Taylor ◽

...

Keyword(s):

Respiratory Syncytial Virus ◽

Human Respiratory Syncytial Virus ◽

Virus Fusion ◽

Conformational Constraints ◽

Fusion Glycoprotein ◽

Syncytial Virus ◽

Neutralizing Epitopes

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A point mutation in the F1 subunit of human respiratory syncytial virus fusion glycoprotein blocks its cell surface transport at an early stage of the exocytic pathway

Journal of General Virology ◽

10.1099/0022-1317-77-4-649 ◽

1996 ◽

Vol 77 (4) ◽

pp. 649-660 ◽

Author(s):

J. A. Lopez ◽

R. Bustos ◽

A. Portela ◽

B. Garcia-Barreno ◽

J. A. Melero

Keyword(s):

Respiratory Syncytial Virus ◽

Cell Surface ◽

Point Mutation ◽

Early Stage ◽

Human Respiratory Syncytial Virus ◽

Surface Transport ◽

Virus Fusion ◽

Fusion Glycoprotein ◽

Syncytial Virus ◽

Exocytic Pathway

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Conformational studies of a short linear peptide corresponding to a major conserved neutralizing epitope of human respiratory syncytial virus fusion glycoprotein

Biopolymers ◽

10.1002/(sici)1097-0282(199610)39:4<537::aid-bip6>3.0.co;2-y ◽

1998 ◽

Vol 39 (4) ◽

pp. 537-548 ◽

Author(s):

Catherine Toiron ◽

Juan A. López ◽

Germán Rivas ◽

David Andreu ◽

José A. Melero ◽

...

Keyword(s):

Respiratory Syncytial Virus ◽

Human Respiratory Syncytial Virus ◽

Neutralizing Epitope ◽

Conformational Studies ◽

Linear Peptide ◽

Virus Fusion ◽

Fusion Glycoprotein ◽

Syncytial Virus

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Stability Characterization of a Vaccine Antigen Based on the Respiratory Syncytial Virus Fusion Glycoprotein

PLoS ONE ◽

10.1371/journal.pone.0164789 ◽

2016 ◽

Vol 11 (10) ◽

pp. e0164789 ◽

Author(s):

Jessica A. Flynn ◽

Eberhard Durr ◽

Ryan Swoyer ◽

Pedro J. Cejas ◽

Melanie S. Horton ◽

...

Keyword(s):

Respiratory Syncytial Virus ◽

Vaccine Antigen ◽

Virus Fusion ◽

Fusion Glycoprotein ◽

Syncytial Virus

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Immunological response of mice to the bovine respiratory syncytial virus fusion glycoprotein expressed in recombinant baculovirus infected insect cells

Archives of Virology ◽

10.1007/bf01718633 ◽

1996 ◽

Vol 141 (12) ◽

pp. 2313-2326 ◽

Author(s):

K. Walravens ◽

J. P. Matheise ◽

I. Knott ◽

P. Coppe ◽

A. Collard ◽

...

Keyword(s):

Respiratory Syncytial Virus ◽

Insect Cells ◽

Recombinant Baculovirus ◽

Immunological Response ◽

Bovine Respiratory Syncytial Virus ◽

Virus Fusion ◽

Fusion Glycoprotein ◽

Infected Insect ◽

Syncytial Virus

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Conformational constraints of neutralizing epitopes from a major antigenic area of the human respiratory syncytial virus fusion (F) glycoprotein

Peptides ◽

10.1007/978-94-011-0683-2_237 ◽

1994 ◽

pp. 719-720

Author(s):

D. Andreu ◽

J. A. López ◽

C. Carreño ◽

G. Taylor ◽

J. A. Melero

Keyword(s):

Respiratory Syncytial Virus ◽

Human Respiratory Syncytial Virus ◽

Virus Fusion ◽

Conformational Constraints ◽

Syncytial Virus ◽

Neutralizing Epitopes

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Polyclonal and monoclonal antibodies specific for the six-helix bundle of the human respiratory syncytial virus fusion glycoprotein as probes of the protein post-fusion conformation

Virology ◽

10.1016/j.virol.2014.05.001 ◽

2014 ◽

Vol 460-461 ◽

pp. 119-127 ◽

Author(s):

Concepción Palomo ◽

Vicente Mas ◽

Mónica Vázquez ◽

Olga Cano ◽

Daniel Luque ◽

...

Keyword(s):

Monoclonal Antibodies ◽

Respiratory Syncytial Virus ◽

Human Respiratory Syncytial Virus ◽

Helix Bundle ◽

Virus Fusion ◽

Fusion Glycoprotein ◽

Syncytial Virus

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Respiratory syncytial virus fusion nanoparticle vaccine immune responses target multiple neutralizing epitopes that contribute to protection against wild-type and palivizumab-resistant mutant virus challenge

Vaccine ◽

10.1016/j.vaccine.2018.10.073 ◽

2018 ◽

Vol 36 (52) ◽

pp. 8069-8078 ◽

Author(s):

Brian E. Gilbert ◽

Nita Patel ◽

Hanxin Lu ◽

Ye Liu ◽

Mimi Guebre-Xabier ◽

...

Keyword(s):

Respiratory Syncytial Virus ◽

Immune Responses ◽

Resistant Mutant ◽

Mutant Virus ◽

Wild Type ◽

Virus Challenge ◽

Virus Fusion ◽

Syncytial Virus ◽

Neutralizing Epitopes

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Safety and immunogenicity of a respiratory syncytial virus fusion glycoprotein F subunit vaccine in healthy adults: Results of a phase 1, randomized, observer-blind, controlled, dosage-escalation study

Vaccine ◽

10.1016/j.vaccine.2019.04.011 ◽

2019 ◽

Vol 37 (20) ◽

pp. 2694-2703 ◽

Author(s):

Geert Leroux-Roels ◽

Fien De Boever ◽

Cathy Maes ◽

Thi Lien-Anh Nguyen ◽

Sherryl Baker ◽

...

Keyword(s):

Respiratory Syncytial Virus ◽

Subunit Vaccine ◽

Phase 1 ◽

Healthy Adults ◽

Virus Fusion ◽

Dosage Escalation ◽

Fusion Glycoprotein ◽

Syncytial Virus

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