scholarly journals Possibility of Application of Extracellular Protease of the Micromycetе Aspergillus ochraceus VKM F-4104D for Determination of the Protein C Content in Human Blood Plasma

2018 ◽  
Vol 12 (2) ◽  
pp. 164-166
Author(s):  
A. A. Osmolovskiy ◽  
A. V. Orekhova ◽  
V. G. Kreyer ◽  
N. A. Baranova ◽  
N. S. Egorov
2018 ◽  
Vol 64 (1) ◽  
pp. 115-118
Author(s):  
A.A. Osmolovskiy ◽  
A.V. Orekhova ◽  
V.G. Kreyer ◽  
N.A. Baranova ◽  
N.S. Egorov

It was shown that the activator activity of protein C, determined in normal plasma using Aspergillus ochraceus protease, is comparable with the activity of commercial protease analogue from the South American copperhead venom (ProtacÒ). It was found that protease of A. ochraceus can be used to determine protein C in plasma with its reduced content similar to ProtacÒ. Comparison of the activator protein C activity of A. ochraceus protease and the commercial analogue showed some excess of the activator activity of the fungal preparation, which may make it a promising substitute for the snake activator in diagnostical kits for determining the protein C content in clinical laboratories.


2020 ◽  
Vol 56 (1) ◽  
pp. 32-36 ◽  
Author(s):  
S. K. Komarevtsev ◽  
E. A. Popova ◽  
V. G. Kreyer ◽  
K. A. Miroshnikov ◽  
A. A. Osmolovskiy

1996 ◽  
Vol 40 (4) ◽  
pp. 175-181 ◽  
Author(s):  
Toshiko Ueda ◽  
Tsuyoshi Maekawa ◽  
Daikai Sadamitsu ◽  
Ryosuke Tsuruta ◽  
Kazuyuki Nakamura

2017 ◽  
Vol 0 (1 (5)) ◽  
pp. 22-32 ◽  
Author(s):  
Igor Kuznetsov ◽  
Helen Naumenko ◽  
Nataliia Reznichenko ◽  
Andrey Kostiuk ◽  
Roman Savyak ◽  
...  

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