The preparation and characterization of 2-propylphosphinediacetic acid
1988 ◽
Vol 53
(5)
◽
pp. 995-998
◽
Keyword(s):
Phosphineacetic acids of the RP(CH2COOH)2 type, where R is a large substituent with a +I-effect, cannot be prepared by the reaction of chlorophosphine with an organozinc compound because of the lability of the P-CH2COO bonds. The bis(ethyl ester) of 2-propylphosphinediacetic acid as the simplest substance of this kind was prepared by the reaction of chlorophosphine with ethylacetate enolate, which is universal for these substituents. 2-Propylphosphinediacetic acid, obtained from the ester by the usual procedure, was characterized with respect to its use as a hydrophilic phosphine ligand.
Keyword(s):
2000 ◽
Vol 605
(1)
◽
pp. 15-21
◽
Keyword(s):
1998 ◽
pp. 317-320
◽
1992 ◽
Vol 267
(19)
◽
pp. 13217-13221
Keyword(s):
Keyword(s):