Unusual presentation of chronic eosinophilic pneumonia with mild peripheral eosinophilia

2021 ◽  
Vol 14 (2) ◽  
pp. e234914
Author(s):  
Rishikesh Meena ◽  
Abhishek Goyal ◽  
Shashwat Kirti Keshri ◽  
Alkesh Kumar Khurana
Keyword(s):  
Lung Diseases ◽  
Eosinophilic Pneumonia ◽  
Pulmonary Eosinophilia ◽  
Unknown Aetiology ◽  
Peripheral Eosinophilia ◽  
Blood Eosinophilia ◽  
Chronic Eosinophilic Pneumonia ◽  
Diffuse Parenchymal Lung Diseases ◽  
Peripheral Blood Eosinophilia ◽  
Parenchymal Lung

Chronic eosinophilic pneumonia (CEP) is a rare disorder of unknown aetiology which comes under the class of diffuse parenchymal lung diseases with eosinophilia. It is classically characterised by blood and pulmonary eosinophilia, peripheral consolidation on chest radiograph and prompt response to corticosteroid therapy. We report a case of CEP in a 66-year-old man, smoker showing bilateral pulmonary infiltrates with mild peripheral eosinophilia. Our study shows that CEP can be kept as a possibility if radiological pictures are consistent, even if peripheral blood eosinophilia is mild.

Eosinophilic pneumonia in the allergist's practice

2021 ◽  
Author(s):  
Tsarev S.V. Tsarev
Keyword(s):  
Bronchoalveolar Lavage ◽  
Lung Diseases ◽  
Bronchoalveolar Lavage Fluid ◽  
Lavage Fluid ◽  
Eosinophilic Pneumonia ◽  
Pulmonary Eosinophilia ◽  
Blood Eosinophilia ◽  
Chronic Eosinophilic Pneumonia ◽  
Autoimmune Processes ◽  
Peripheral Blood Eosinophilia

Pulmonary eosinophilia is defined as infiltration of eosinophils into the lungs airways, interstitium, and alveoli. Various infections, drugs, parasites, autoimmune processes, malignancies and obstructive lung diseases have been associated with increased eosinophils in the lungs The eosinophilic pneumonias are a heterogeneous group of diseases characterized by an increase in eosinophils in lung tissue or bronchoalveolar lavage fluid. Many, but not all, of the eosinophilic pneumonias are also associated with a peripheral blood eosinophilia. The two main variants of the disease are acute and chronic eosinophilic pneumonia

scholarly journals Diagnostic approach in parenchymal lung diseases: transbronchial lung biopsy or cryobiopsy?

2020 ◽  
Vol 50 (6) ◽  
pp. 1535-1539
Author(s):  
Ali Kadri ÇIRAK ◽  
Nuran KATGI ◽  
Onur Fevzi ERER ◽  
Pınar ÇİMEN ◽  
Fatma Fevziye TUKSAVUL ◽  
...  
Keyword(s):  
Lung Biopsy ◽  
Lung Diseases ◽  
Interstitial Lung Diseases ◽  
Massive Hemorrhage ◽  
Open Lung Biopsy ◽  
Transbronchial Lung Biopsy ◽  
Diffuse Parenchymal Lung Diseases ◽  
Training And Research ◽  
Transbronchial Lung Cryobiopsy ◽  
Parenchymal Lung

Background/aim: Diagnosis of interstitial lung diseases requires a multidisciplinary approach, and a gold standard for histological diagnosis is open lung biopsy. Transbronchial lung biopsy (TBLB) and in recent years an alternative method, cryobiopsy (TBLC), are used for the diagnosis of parenchymal lung lesions. The aim of this study is to compare the efficacy of concomitant conventional TBLB and TBLC.Materials and methods: A total of 82 patients who underwent TBLC for diagnosis of diffuse parenchymal lung diseases at Dr. Suat Seren Chest Diseases and Surgery Training and Research Hospital between 2015 and 2018 were screened retrospectively and included in the study. Of the patients, 53.7% (n: 44) were male, and 46.4% (n:38) of them were female. The mean age was 58.37 (±9.33) years. First TBLB and then TBLC were performed to all patients in the same session and their diagnostic performances were compared.Results: Although both procedures were done in the same session, 45 patients (54.9%) were diagnosed with TBLB and 75 patients (91.5%) were diagnosed with TBLC (P ˂ 0.001). Hemorrhage was observed in 39 patients (47.6%), but only one had a massive hemorrhage. Pneumothorax was observed in 6 patients (7.3%) and none of them required tube drainage.Conclusion: Transbronchial lung cryobiopsy is a promising technique for the diagnosis of parenchymal lung diseases compared to transbronchial lung biopsy.

scholarly journals Concurrent sensitization to Aspergillus Fumigatus in tropical pulmonary eosinophilia

2016 ◽  
Vol 81 (1-2) ◽  
Author(s):  
Sunil K. Chhabra ◽  
Devi Jyoti Dash
Keyword(s):  
Aspergillus Fumigatus ◽  
Severe Asthma ◽  
Lung Tissue ◽  
Peripheral Blood ◽  
Allergic Bronchopulmonary Aspergillosis ◽  
Pulmonary Eosinophilia ◽  
Blood Eosinophilia ◽  
Future Risk ◽  
Serum Total Ige ◽  
Peripheral Blood Eosinophilia

<p>Tropical pulmonary eosinophilia (TPE) is characterized by lung tissue and peripheral blood eosinophilia. Serum total IgE is also markedly increased in TPE. However, an association with asthma or other hypersensitivity conditions has not been described. During the diagnostic workup of three patients eventually confirmed to have TPE, hypersensitivity to the fungus, <em>Aspergillus Fumigatus </em>was found. However, there was no evidence of diseases of aspergillus hypersensitivity such as severe asthma with fungal sensitization (SAFS) and allergic bronchopulmonary aspergillosis (ABPA). This association however raises the possibility of a future risk of these potentially serious allergic respiratory manifestations.</p><p><strong>Riassunto</strong></p><p>L’eosinofilia polmonare tropicale (TPE) è caratterizzata da tessuto polmonare e eosinofilia nel sangue periferico. Anche il siero IgE totale è notevolmente aumentato in TPE. Tuttavia, un’associazione con asma o altre condizioni di ipersensibilità non è stata descritta. Durante l'iter diagnostico di tre pazienti, che alla fine si sono rivelati presentare TPE, ipersensibilità al fungo, è stato trovato l’<em>Aspergillus fumigatus</em>. Tuttavia, non vi era alcuna evidenza di malattie di <em>Aspergillus</em> ipersensibilità come l'asma grave con sensibilizzazione fungina (SAF) e aspergillosi broncopolmonare allergica (ABPA). Questa associazione pone tuttavia la possibilità di un rischio futuro di queste potenzialmente gravi manifestazioni allergiche respiratorie.</p>

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